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http://dx.doi.org/10.4046/trd.2009.67.6.556

A Case of Acute Eosinophilic Pneumonia Associated with Intramuscular Administration of Progesterone Following In Vitro Fertilization  

Park, Sung Keun (Department of Internal Medicine, Gachon University of Medicine and Science)
Choi, Byoung Ho (Department of Internal Medicine, Gachon University of Medicine and Science)
Chon, Su Yeon (Department of Internal Medicine, Gachon University of Medicine and Science)
Kim, Yu Jin (Department of Internal Medicine, Gachon University of Medicine and Science)
Kyung, Sun Young (Department of Internal Medicine, Gachon University of Medicine and Science)
Lee, Sang Pyo (Department of Internal Medicine, Gachon University of Medicine and Science)
Jeong, Sung Hwan (Department of Internal Medicine, Gachon University of Medicine and Science)
Park, Jeong-Woong (Department of Internal Medicine, Gachon University of Medicine and Science)
Publication Information
Tuberculosis and Respiratory Diseases / v.67, no.6, 2009 , pp. 556-559 More about this Journal
Abstract
Acute eosinophilic pneumonia (AEP) is characterized by idiopathic acute febrile illness, diffuse pulmonary infiltration, severe hypoxemia, and pulmonary eosinophilia. We report a case of AEP associated with intramuscular administration of progesterone as luteal phase support after in vitro fertilization. A 33-year-old woman presented to our emergency room with tachypnea and hypoxemia, complaining of fever and cough for 4 days, and dyspnea for 2 days. The symptoms began 9 days after the first injection of progesterone. Chest radiograph showed bilateral infiltrates, located predominantly in the periphery of the lungs, with blunting of the costophrenic angle. Symptoms and chest radiograph dramatically improved after corticosteroid therapy and shifting the progesterone from an intramuscular form of administration to a vaginal form of administration.
Keywords
Pulmonary Eosinophilia; Progesterone; Eosinophilia;
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