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A Case of Multiple Micronodular Pneumocyte Hyperplasia of the Lung in a Man with Tuberous Sclerosis  

Nam, Dong Hyuk (Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital)
Choi, Yoon Jung (Department of Pathology, National Health Insurance Corporation Ilsan Hospital)
Lee, Ju Hyun (Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital)
Na, Hyoung Jung (Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital)
Kim, Dong Hwan (Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital)
Kim, Chong Ju (Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital)
Lee, Sun Min (Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital)
Hong, Yong Kug (Department of Radiology, National Health Insurance Corporation Ilsan Hospital)
Han, Chang Hoon (Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital)
Publication Information
Tuberculosis and Respiratory Diseases / v.64, no.5, 2008 , pp. 369-373 More about this Journal
Abstract
Tuberous sclerosis (TS) is an autosomal dominant disorder that is characterized by cutaneous lesions, seizures, mental retardation and hamartomas in various organs including the skin, kidney and brain. Pulmonary involvement is extremely rare, and occurs in approximately 0.1 to 1% of TS cases. Recent reports have indicated multiple micronodular pneumocyte hyperplasia (MMPH) as another rare form of pulmonary involvement of tuberous sclerosis. We report a case of a 35 year-old-male patient who had no pulmonary symptoms but showed multinodular pulmonary shadows on his chest CT scan. The patient was finally diagnosed with TS with MMPH of the lung. MMPH does not appear to have any malignant potential but the clinical significance of MMPH in TS patients is unknown.
Keywords
Tuberous sclerosis; Multiple micronodular pneumocyte hyperplasia;
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