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Fatal Tumor Lysis Syndrome During Chemotherapy in Small Cell Lung Cancer  

Kook, Eun Hee (Department of Internal Medicine, Korea Cancer Center Hospital)
Kim, Min Soo (Department of Internal Medicine, Korea Cancer Center Hospital)
Ahn, Se Han (Department of Internal Medicine, Korea Cancer Center Hospital)
Jeon, Se Young (Department of Internal Medicine, Korea Cancer Center Hospital)
Yoon, Jung Ho (Department of Internal Medicine, Korea Cancer Center Hospital)
Han, Min Sung (Department of Internal Medicine, Korea Cancer Center Hospital)
Kim, Cheol Hyeon (Department of Internal Medicine, Korea Cancer Center Hospital)
Lee, Jae Cheol (Department of Internal Medicine, Korea Cancer Center Hospital)
Publication Information
Tuberculosis and Respiratory Diseases / v.64, no.3, 2008 , pp. 215-218 More about this Journal
Abstract
Tumor lysis syndrome is a life-threatening complication of anti-cancer therapy that typically occurs in patients with large, rapidly growing and treatment-sensitive tumors such as high-grade lymphomas and acute leukemias. However, its incidence in solid tumors has been known to be very low. Tumor lysis syndrome in solid tumors has a high mortality rate owing to the lack of prophylactic therapy to prevent this complication. We report a case of fatal tumor lysis syndrome developed during chemotherapy in extensive-stage small cell lung cancer, along with a brief review of the relevant literature considering the rarity of this manifestation in solid tumor.
Keywords
Small cell lung cancer; Tumor lysis syndrome;
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