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A Case of Different Response of Miliary Lung and Intracranial Nodules to Antituberculous Therapy  

Park, Kwang Young (Department of Internal Medicine, Korea Cancer Center Hospital)
Lee, Ho Jin (Department of Internal Medicine, Korea Cancer Center Hospital)
Jung, Jae Wook (Department of Internal Medicine, Korea Cancer Center Hospital)
Choi, Yoon Hee (Department of Internal Medicine, Korea Cancer Center Hospital)
Nam, Seung Bum (Department of Internal Medicine, Korea Cancer Center Hospital)
Ahn, Se Han (Department of Internal Medicine, Korea Cancer Center Hospital)
Kim, Cheol Hyeon (Department of Internal Medicine, Korea Cancer Center Hospital)
Lee, Jae Cheol (Department of Internal Medicine, Korea Cancer Center Hospital)
Publication Information
Tuberculosis and Respiratory Diseases / v.64, no.2, 2008 , pp. 153-157 More about this Journal
Abstract
Although a paradoxical response of tuberculosis to antituberculous therapy is not a rare phenomenon, it can be a clinical challenge to differentiate a paradoxical response from treatment failure. A 25-year-old woman was admitted for miliary lung nodules and multiple intracranial nodules. Antituberculous treatment was started with a preliminary diagnosis of tuberculosis based on the history and clinical findings. After one month, the military lung nodules improved while the intracranial nodules increased in size and number. Based on a stereotactic biopsy, it was confirmed that the intracranial lesions were tuberculomas. Although the therapeutic regimen was not changed, the symptoms eventually were ameliorated and the intracranial nodules improved two months later.
Keywords
Tuberculosis; Paradoxical response; Intracranial tuberculoma;
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