The Efficacy of Added Montelukast in Persistent Asthmatics Who Were Not Completely Controlled on Inhaled Corticosteroids and Inhaled Long-acting β2-agonists
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Choi, Jeong-Hee
(Department of Internal Medicine, College of Medicine, Hallym University)
Park, Hae-Sim (Department of Internal Medicine, College of Medicine, Ajou University) Lee, Kwan-Ho (Department of Internal Medicine, College of Medicine, Yeungnam University) Shim, Jae-Jeong (Department of Internal Medicine, College of Medicine, Korea University) Uh, Soo-Taek (Department of Internal Medicine, College of Medicine, Soonchunhyang University) Lee, Sang-Pyo (Department of Internal Medicine, College of Medicine, Gachon University) Lee, Yong-Chul (Department of Internal Medicine, College of Medicine, Chonbuk National University) Choi, Won-Il (Department of Internal Medicine, College of Medicine, Keimyung University) Lee, Jae-Ho (Department of Internal Medicine, College of Medicine, Seoul National University) Kim, Joo-In (Department of Internal Medicine, College of Medicine, Inje University) Lee, Myung-Goo (Department of Internal Medicine, College of Medicine, Hallym University) Jung, Ki-Suck (Department of Internal Medicine, College of Medicine, Hallym University) |
1 | Busse WW, O'Byrne PM, Holgate ST. Chapter 66. Asthma pathogenesis. In; Adkinson NF Jr, Yunginger JW, Busse WW, Bochner BS, Holgate ST, Simons FE. editors. Middlewn's allergy. Principles and practices. 6th ed. Philadelphia: Mosby, Inc.; 2003. p. 1175-207 |
2 | Global strategy for asthma management and prevention (Revised 2(03): Global initiative for asthma (GINA). Available from: http://ginasthma.org |
3 | Szefler SJ, Martin RI, King TS, Boushey HA, Cherniack RM, Chinchilli VM, et al. Significant variability in response w inhaled corticosteroids for persistent asthma. J Allergy Clin Immunol 2002;109:410-8 DOI ScienceOn |
4 | Schleimer W, Spahn JD, Ccvar R, Szefler SJ. Chapter 52. Glucocorticoids. In: Adkinson NF Jr, Yunginger JW, Busse WW, Boehner BS, Holgate ST, Simons FE, editors. Middleton's allergy. Principles and practices. 6th ed. Philadelphia: Mosby, Inc.; 2003. p. 870-913 |
5 | Lewis RA, Austen KF, Sobelman RJ. Leukotrienes and other products of the 5-lipoxygenase pathway. N Engl J Med 1990;323:645-65 DOI ScienceOn |
6 |
Dupont L, Pohin E, Rom D, Lachman A, Dramaix M, Gusman J, et al. Improving asthma control in patient, suboptimally controlled on inhaled steroids and long-acting |
7 | Juniper EF, O'Byrne PM, Guyatt GH, Ferrie PJ, King DR. Development and validation of a questionnaire to measure asthma control. Eur Respir J 1999;14:902-7 DOI ScienceOn |
8 | Malonne H, Lachman A, Van den Brande P. Tmpact of montelukast on symptoms in mild-to-moderate persistent asthma and exercise-induced asthma: results of the asthma survey. Curr Med Res Opin 2002;18:512-9 DOI ScienceOn |
9 | Philip G, Nayak AS, Berger WE, Leynadier F, Vrijens F, Dass SB, et al. The effect of montelukast on rhinitis symptoms in patients with asthma and seasonal allergic rhinitis. Curr Med Res Opin 2004;20:1549-68 DOI ScienceOn |
10 | Barnes NC, Miller CJ. Ellect of leukotriene receptor antagonists therapy on the risk of asthma exacerbations in patients with mild to moderate asthma: an integrated analysis of zafirlukast trials. Thorax 2000;55:478-83 DOI ScienceOn |
11 | Sahi SS, Krishna MT, Sampson AP, Holgate ST. The anti-inflammatory effects of leukotliene-modifying drugs and their use in asthma. Chest 2001;119: 1633-46 DOI ScienceOn |
12 | Henderson WR Jr. The role of leukotrienes in inflammation. Ann Intern Med 1994;121:684-97 DOI ScienceOn |
13 | Bateman ED, Barshey HA, Bousquet J, Busse WW, Clark TJ, Pauwels RA, et al. Can guideline-defined asthma control be achieved? The gaining optimal asthma control study. Am J Respir Crit Care Med 2004;170:836-44 DOI ScienceOn |
14 | Lipworth BJ. Leulkomene-receptor antagonists. Lancet 1999;353:57-62 DOI ScienceOn |
15 | Currie GP, Lee DK, Haggart K, Bates CE, Lipworth BJ. Effects of montelukast on sunugate inflammatory markers in corticosteroid treated asthmatics. Am J Respir Crit Care Med 2003;167:1232-8 DOI ScienceOn |
16 | Ducharme FM, Lesserson TJ, Cates CJ. Long-acting beta2-agonists versus anti-leukotrienes as add-on therapy to inhaled corticostemids for chronic asthma. Cochrane Database Syst Rev 2006;18:CD003137 |
17 | Bjermer L, Bisgaaru H, Bousquet J, Fabbri LM, Greening AP, Haahtela T, et al. Motelukast and fluticasone compared with salmeteml and fluticasone in protecting against asthma exacerhation in adult: one year, double blind, randomized, comparative trial. BMJ 2003;327:891 DOI ScienceOn |
18 |
Deykin A, Wechsler ME, Boushey HA, Chinchilli VM, Kunselman SJ, Craig TJ, et al. Comhination theerapy with a long acting |
19 | Drazen JM, Israel E, O'Byrne PM. Treatment of asthma with drugs modifying the leukotriene pathway. N Engl J Med 1999;340:197-206 DOI ScienceOn |
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