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A Case of Primary Antiphospholipid Syndrome with Pulmonary Thromboembolism  

Lee, Jae Beom (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Sim, Yun Su (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Noh, Young Wook (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Park, Hye Sung (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Tae, Chung Hyun (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Lim, So Yeon (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Jun, Yoon Hee (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Ryu, Yon Ju (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Chun, Eun Mi (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Lee, Jin Hwa (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Chang, Jung Hyun (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Moon, Jin Wook (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Publication Information
Tuberculosis and Respiratory Diseases / v.63, no.1, 2007 , pp. 72-77 More about this Journal
Abstract
Antiphospholipid syndrome (APS) causes recurrent thromboses and morbidity during pregnancy, including fetal loss. This malady is associated with the persistent presence of anticardiolipin antibody or lupus anticoagulant. The pulmonary manifestations of antiphospholipid syndrome include pulmonary thromboembolism, pulmonary hypertension, acute respiratory distress syndrome, etc. Pulmonary thromboembolism is often the initial manifestation of antiphospholipid syndrome and a timely diagnosis is critical due to the high mortality rate. We herein report on a 19-year-old man with pulmonary thromboembolism that was caused by primary antiphospholipid syndrome. He presented with blood-tinged sputum, fever and epigastric pain, and his chest computerized tomography showed pulmonary thromboembolism. The other possible causes of pulmonary thromboembolism were excluded and the diagnosis of primary antiphospholipid syndrome was confirmed by the lupus anticoagulant that was present on two occasions six weeks apart. We also discuss the nature and management of antiphospholipid syndrome, along with a brief review of the relevant literatures.
Keywords
Antiphospholipid syndrome; Pulmonary thromboembolism; Thrombosis;
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