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A Case of Acute Respiratory Distress Syndrome Caused By Zinc Fume Inhalation  

Choi, Sang Bun (Department of Internal Medicine, College of Medicine, Inje University)
Seo, Jeong Sook (Department of Internal Medicine, College of Medicine, Inje University)
Han, Yang Chun (Department of Internal Medicine, College of Medicine, Inje University)
Kim, Ae Ran (Department of Internal Medicine, College of Medicine, Inje University)
Hur, Jin-Won (Department of Internal Medicine, College of Medicine, Inje University)
Lee, Sung Soon (Department of Internal Medicine, College of Medicine, Inje University)
Lee, Young Min (Department of Internal Medicine, College of Medicine, Inje University)
Lee, Hyuk Pyo (Department of Internal Medicine, College of Medicine, Inje University)
Kim, Joo In (Department of Internal Medicine, College of Medicine, Inje University)
Yum, Ho-Kee (Department of Internal Medicine, College of Medicine, Inje University)
Choi, Suk-Jin (Department of Radiology, College of Medicine, Inje University)
Choi, Soo Jeon (Department of Internal Medicine, College of Medicine, Inje University)
Lee, Hyun-Kyung (Department of Internal Medicine, College of Medicine, Inje University)
Publication Information
Tuberculosis and Respiratory Diseases / v.62, no.4, 2007 , pp. 314-317 More about this Journal
Abstract
The Inhalation of certain freshly formed metal oxides can cause metal fume fever, which is an acute, self-limiting, flu-like illness. The most common cause of this syndrome is the inhalation of zinc oxide. The inhalation of zinc oxide can lead to tracheobronchiolitis, chemical pulmonary edema or to respiratory failure and acute respiratory distress syndrome(ARDS). We encountered a 43-years-old man who developed severe dyspnea after inhaling of zinc oxide while working for 5 hours in a closed space. He was diagnosed with ARDS and was treated successfully with glucocorticoid. We report a case of ARDS caused by the inhalation of zinc fumes.
Keywords
Zinc fume inhalation; Acute respiratory distress syndrome; Glucocorticoid; N-acetylcysteine;
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1 Elinder CG, Zenz C. Chapter 46. Other Metals and their compounds. In: Zenz C, Dickerson OB, Horvath EP, editors. Occupational medicine. 3rd ed. St. Louis, Missouri: Mosby, Inc.; 1994. p.595-616
2 Rose CS. Inhalation fevers. In: Rom WN, editor. Environmental and occupational medicine. 2nd ed. Boston: Little, Brown & Co.; 1992. p.376-7
3 Hsu HH, Tzao C, Chang WC, Wu CP, Tung HJ, Chen CY, et al. Zinc chloride (smoke bomb) inhalation lung injury: clinical presentations, high -resolution CT findings, and pulmonary function test results. Chest 2005;127:2064-71   DOI   ScienceOn
4 Lim HS, Cheong HK. A case of metal fume fever associated with copper fume in a welder. Korean J Prev Med 1998;31:414-23
5 Lefering R, Neugebauer EA. Steroid controversy in sepsis and septic shock: a meta-analysis. Crit Care Med 1995;23:1294-303   DOI   ScienceOn
6 Hjortso E, Qvist J, Bud MI, Thomsen JL, Andersen JB, Wilberg-Jorgensen F, et al. ARDS after accidental inhalation of zinc chloride smoke. Intensive Care Med 1998;14:17-24   DOI
7 Balmes JR. Chapter 20. Occupational lung diseases. In: LaDou J, editor. Current occupational & environmental medicine. 3rd ed. Lange: McGraw-Hill, Inc.; 2004. p.320-44
8 Kuschner WG, D'Alessandro A, Wong H, Blanc PD. Early pulmonary cytokine responses to zinc oxide fume inhalation. Environ Res 1997;75:7-11   DOI   ScienceOn
9 Anseline P. Zinc fume fever. Med J Aust 1972;2:316-8
10 Libby P, Friedman GB, Salomon RN. Cytokines as modulators of cell proliferation in fibrotic disease. Am Rev Respir Dis 1989;140:1114-7   DOI   ScienceOn
11 Homma S, Jones R, Qvist J, Zapol WM, Reid L. Pulmonary vascular lesions in adult respiratory distress syndrome caused by inhalation of zinc chloride smoke: a morphometric study. Hum Pathol 1992;23:45-50   DOI   ScienceOn
12 Evans EH. Casualties following exposure to zinc chloride smoke. Lancet 1945;2:368-70
13 Pettila V, Takkunen O, Tukiainen P. Zinc chloride smoke inhalation: a rare cause of severe acute respiratory distress syndrome. Intensive Care Med 2000;26:215-7   DOI   ScienceOn