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A Case of Pulmonary Thromboembolism in a Patient with Hyperhomocysteinemia  

Oh, Sook Eui (Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University Medical Center)
Jung, Jae-Hun (Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University Medical Center)
Yoon, Seong Bo (Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University Medical Center)
Yoon, Hyeon Young (Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University Medical Center)
Park, Jong Kyu (Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University Medical Center)
Lee, Dong Hun (Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University Medical Center)
Hong, Sung Ho (Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University Medical Center)
Woo, Kung Hee (Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University Medical Center)
Choi, Seonghoon (Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University Medical Center)
Lee, Sang Hak (Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University Medical Center)
Lee, Namho (Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University Medical Center)
Publication Information
Tuberculosis and Respiratory Diseases / v.62, no.3, 2007 , pp. 211-216 More about this Journal
Abstract
Hyperhomocysteinemia is an independent risk factor for cardiovascular, cerebrovascular and peripheral vascular diseases that are complicated by atherosclerosis and a thromboembolism. An increased level of plasma homocysteine develops from a genetic defect in the of enzyme for the homocysteine metabolism or a vitamin deficiency. Hyperhomocysteinemia has direct toxic effect on the vascular endothelium and causes damages to the antithrombotic action of vascular endothelial cells. Most cases of hyperhomocysteinemia are asymptomatic, but cardiopulmonary or cerebrovascular incidents developin rare cases. In the case of a thromboembolism with an unknown cause, hyperhomocysteinemia should be considered in a differential diagnosis. The authors report a case of pulmonary thromboembolism in a patient with hyperhomocysteinemia with a review of the relevant literature.
Keywords
Hyperhomocysteinemia; Pulmonary embolism;
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