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The Characteristics of Eosinophilc Lung Diseases Cause by Toxocara Canis Larval Infestation  

Kim, Yu Jin (Department of Internal Medicine Gachon University, Gil Medical Center)
Kyung, Sun Young (Department of Internal Medicine Gachon University, Gil Medical Center)
An, Chang Hyeok (Department of Internal Medicine Gachon University, Gil Medical Center)
Lim, Young Hee (Department of Internal Medicine Gachon University, Gil Medical Center)
Park, Jung Woong (Department of Internal Medicine Gachon University, Gil Medical Center)
Jeong, Seong Hwan (Department of Internal Medicine Gachon University, Gil Medical Center)
Lee, Sang Pyo (Department of Internal Medicine Gachon University, Gil Medical Center)
Choi, Dong Chull (Department of Internal Medicine Sungkyunkwan University)
Jeong, Young Bae (Department of Parasitology, Cheju National University)
Kang, Shin Yong (Department of Parasitology, Chung Ang University)
Publication Information
Tuberculosis and Respiratory Diseases / v.62, no.1, 2007 , pp. 19-26 More about this Journal
Abstract
Background: Toxocariasis is a common cause of eosinophilia and eosinophilic lung disease in Korea. We analyzed the characteristics of eosinophilic lung disease in toxocariasis. Method: One hundred and forty one patients with eosinophilia caused by a toxocara larval infection were evaluated from September 1, 2001 through March 30, 2006. The plain chest x-ray, chest CT(computed tomography), and bronchoalveolar larvage(BAL) were examined. A diagnosis of toxocariasis was made by ELISA using that secretory-excretory antigen from the T. canis larvae. Results: Toxocarial eosinophilic lung diseases was diagnosed in 32 out of 141 patients. Ground glass attenuation was the main feature on the CT scans in 23 out of 141 patients (71.9%). Thirteen patients (40.6%) had a random in zonal distribution on CT. Pleural effusion was observed in 9 patients (28.1%). Twenty eight patients (87.5%) complained of respiratory symptoms. Eleven patients (34.4%) had gastrointestinal symptoms and 12 patients (37.5%) had liver infiltration. Conclusions: The most common findings of the chest CT in patients with toxocariasis was a randomly distributed ground grass attenuation. A toxocara infection should be considered in a differential diagnosis of patients who exhibit pulmonary infiltration with eosinophilia in Korea.
Keywords
Eosinophilia; Pneumonia; Toxocara; Parasite;
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1 Lee SP. Pathophysiology of hypersensitivity in human by Toxocara canis larval infection. Chung-Ang University Doctoral Thesis. 2001
2 Kwon NH, Oh MJ, Lee SP, Lee BJ, Choi DC. The prevalence and diagnostic value of toxocariasis in unknown eosinophilia. Ann Hematol 2006;85:233-8   DOI   ScienceOn
3 Lim JH, Lee KS. Eosinophilic infiltration in Korea: idiopathic? Korean J Radiol 2006;7:4-6   과학기술학회마을   DOI   ScienceOn
4 Johkoh T, Muller NL, Akira M, Ichikado K, Suga M, Ando M, et al. Eosionophilic lung diseases: diagnostic accuracy of thin-section CT iin 111 patients. Radiology 2000;216:773-80   DOI
5 Deutz A, Fuchs K, Auer H, Kerbl U, Aspock H, Kofer J. Toxocaro-infestations in Austria: a study on the risk of infection of farmers, slaughterhouse staff, hunters and veterinarians. Parasitol Res 2005;97:390-4   DOI   ScienceOn
6 Despommier D. Toxocariasis: clinical aspects, epidemiology, medical ecology, and molecular aspects. Clin Microbiol Rev 2003;16:265-72   DOI   ScienceOn
7 Park HY, Lee SU, Huh S, Kong Y, Magnaval JF. A seroepidemiological survey for toxocariasis in apparently healthy residents in Gangwon-do, Korea. Korean J Parasitol 2002;40:113-7   DOI
8 Beaver PC, Synder CH, Carrera GM, Dent JH, Lafferty JW. Chronic eosinophilia due to visceral larva migrans: report of three cases. Pediatrics 1952; 9:7-19
9 Cheon JE, Lee KS, Jung GS, Chung MH, Cho YD. Acute eosinophilic pneumonia: radiographic and CT findings in six patients. Am J Roentgenol 1996;167: 1195-9   DOI
10 Alberts WM. Eosinophilic intestitial lung disease. Curr Opin Pulm Med 2004;10:419-24   DOI   ScienceOn
11 Allen JN, Davis WB. Eosinophilic lung disease. Am J Respir Crit Care Med 1994;150:1423-38   DOI   ScienceOn
12 Jacquier P, Gttstein B, Stinglin Y, Eckri J. Immunodiagnosis of toxocarosis in humans: evaluation of a new enzyme-linked immunosorbent assay kit. J Clin Microbiol 1991;29:1831-5
13 Mochimaru H, Kawamoto M, Fukuda Y, Kudoh S. Clinicopathological differences between acute and chronic eosinophilic pneumonia. Respilogy 2005;10: 76-85
14 Bernstein IL, Boushey HA, Cherniack RM, Fink JN, Fulmer JD, Goetzl EJ, et al. Summary and recommendations of a workshop on the investigative use of fiberoptic bronchoscopy and bronchoalveolar lavage in asthmatic patients. Chest 1985;88:136-8   DOI   ScienceOn
15 Baldisserotto M, Conchin CF, Soares Mda G, Araujo MA, Kramer B. Ultrasound findings in children with toxocariasis: report on 18 cases. Pediatr Radiol 1999; 29:316-9   DOI   ScienceOn
16 Lee SP, Lim YH, Choi DC. Hepatic infiltration with eosinophilia: is a new disease syndrome? [Abstract] J Allergy Clin Immunol 1999;103: S112
17 Inoue K, Inoue Y, Arai T, Nawa Y, Kashiwa Y, Yamamato S, et al. Chronic eosinophilic pneumonia due to visceral larva migrans. Intern Med 2002; 41:478-82   DOI   ScienceOn
18 Albera C, Ghio P. Eosinophils in eosinophilic pneumonia. Eur Respir J 1996;9:2437-9   DOI   ScienceOn
19 Cho SY, Kong Y, Kim SI, Kang SY. Measurement of 150 kDa protein of Taenia solium metacestodes by antibody-sandwich ELISA in cerebrospinal fluid of neurocysticercosis patients. Korean J Parasitol 1992; 30:299-307   DOI