The Effects of Ethyl Pyruvate on Lipopolysaccharide-induced Acute Lung Injury |
Lee, Seung Hyeun
(Department of Internal Medicine, College of Medicine, Korea University)
Yoon, Dae Wui (Institute of Human Genomic Study, Ansan Hospital, Korea University Medical Center) Jung, Jin Yong (Department of Internal Medicine, College of Medicine, Korea University) Lee, Kyung Joo (Department of Internal Medicine, College of Medicine, Korea University) Kim, Se Joong (Department of Internal Medicine, College of Medicine, Korea University) Lee, Eun Joo (Department of Internal Medicine, College of Medicine, Korea University) Kang, Eun Hae (Department of Internal Medicine, College of Medicine, Korea University) Jung, Ki Hwan (Department of Internal Medicine, College of Medicine, Korea University) Lee, Sung Yong (Department of Internal Medicine, College of Medicine, Korea University) Lee, Sang Yeub (Department of Internal Medicine, College of Medicine, Korea University) Kim, Je Hyeong (Department of Internal Medicine, College of Medicine, Korea University) Shin, Chol (Department of Internal Medicine, College of Medicine, Korea University) Shim, Jae Jeong (Department of Internal Medicine, College of Medicine, Korea University) In, Kwang Ho (Department of Internal Medicine, College of Medicine, Korea University) Kang, Kyung Ho (Department of Internal Medicine, College of Medicine, Korea University) Yoo, Se Hwa (Department of Internal Medicine, College of Medicine, Korea University) |
1 | Mahadev K, Zilbering A, Zhu L, Goldstein BJ. Insulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade. Mahadev K, Zilbering A, Zhu L, Goldstein BJ. Insulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade. J Biol Chem 2001:276:21938-42 2001;276:21938-42 DOI ScienceOn |
2 | Bunger R, Mallet RT, Hartman DA. Pyruvateenhanced phosphorylation potential and inotropism in normoxic and postischemic isolated working heart: near-complete prevention of reperfusion contractile failure. Eur J Biochem 1989:180:221-33 DOI ScienceOn |
3 | Yang R, Uchiyama T, Alber SM, Han X, Watkins SK, Delude RL, et al. Ethyl pyruvate ameliorates distant organ injury in a murine model of acute necrotizing pancreatitis. Crit Care Med 2004:32:1453-9 DOI ScienceOn |
4 | Hirano S. Migratory responses of PMN after intraperitoneal and intratracheal administration of lipopolysaccharide. Am J Physiol 1996:270:L836-45 |
5 | Pelosi P, Caironi P, Gattinoni L. Pulmonary and extrapulmonary forms of acute respiratory distress syndrome. Semin Respir Crit Care Med 2001:22: 259-68 DOI ScienceOn |
6 | Terashima T, Matsubara H, Nakamura M, Sakamaki F, Waki Y, Soejima K, et al. Local pseudomonas instillation induces contralateral lung injury and plasma cytokines. Am J Respir Crit Care Med 1996:153: 1600-5 DOI ScienceOn |
7 | Menezes SL, Bozza PT, Neto HC, Laranjeira AP, Negri EM, Capelozzi VL, et al. Pulmonary and extrapulmonary acute lung injury: inflammatory and ultrastructural analyses. J Appl Physiol 2005:98: 1777-83 DOI ScienceOn |
8 | Schoonbroodt S, Ferreira V, Best-Belpomme M, Boelaert JR, Legrand-Poels S, Korner M, et al. Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress. J Immunol 2000:164:4292-300 DOI |
9 | Janero DR, Hreniuk D, Sharif HM. Hydroperoxide- induced oxidative stress impairs heart muscle cell carbohydrate metabolism. Am J Physiol 1994:266: C179-88 |
10 | Imanaka H, Shimaoka M, Matsuura N, Nishimura M, Ohta N, Kiyono H. Ventilator-induced lung injury is associated with neutrophil infiltration, macrophage activation, and TGF-beta 1 mRNA upregulation in rat lungs. Anesth Analg 2001:92:428-36 DOI |
11 | Dobsak P, Courderot-Masuyer C, Zeller M, Vergely C, Laubriet A, Assem M, et al. Antioxidative properties of pyruvate and protection of the ischemic rat heart during cardioplegia. J Cardiovasc Pharmacol 1999:34: 651-9 DOI ScienceOn |
12 | Livolsi A, Busuttil V, Imbert V, Abraham RT, Peyron JF. Tyrosine phosphorylation-dependent activation of NF-kappa B: requirement for p56 LCK and ZAP-70 protein tyrosine kinases. Eur J Biochem 2001:268: 1508-15 DOI ScienceOn |
13 | Mohr S, Stamler JS, Brune B. Posttranslational modification of glyceraldehyde-3-phosphate dehydrogenase by S-nitrosylation and subsequent NADH attachment. J Biol Chem 1996:271:4209-14 DOI |
14 | Sileri P, Schena S, Morini S, Rastellini C, Pham S, Benedetti E, et al. Pyruvate inhibits hepatic ischemiareperfusion injury in rats. Transplantation 2001:72: 27-30 DOI ScienceOn |
15 | Vonkorff RW. Pyruvate-C14, purity and stability. Anal Biochem 1964:8:171-8 |
16 | Rocco PR, Zin WA. Pulmonary and extrapulmonary acute respiratory distress syndrome: are they different- Curr Opin Crit Care 2005:11:10-7 DOI ScienceOn |
17 | Ulloa L, Ochani M, Yang H, Tanovic M, Halperin D, Yang R, et al. Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation. Proc Natl Acad Sci U S A 2002:99: 12351-6 |
18 | Salahudeen AK, Clark EC, Nath KA. Hydrogen peroxide-induced renal injury: a protective role for pyruvate in vitro and in vivo. J Clin Invest 1991:88:1886-93 DOI |
19 | Pelosi P, D'Onofrio D, Chiumello D, Paolo S, Chiara G, Capelozzi VL, et al. Pulmonary and extrapulmonary acute respiratory distress syndrome are different. Eur Respir J Suppl 2003:42:48s-56s |
20 | Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, et al. The American-European Consensus Conference on ARDS: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 1994:149:818-24 DOI ScienceOn |
21 | Riedemann NC, Guo RF, Ward PA. Novel strategies for the treatment of sepsis. Nat Med 2003:9:517-24 DOI ScienceOn |
22 | Ware LB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med 2000:342:1334-49 DOI ScienceOn |
23 | Cicalese L, Lee K, Schraut W, Watkins S, Borle A, Stanko R. Pyruvate prevents ischemia-reperfusion mucosal injury of rat small intestine. Am J Surg 1996:171:97-100 DOI ScienceOn |
24 | Tawadrous ZS, Delude RL, Fink MP. Resuscitation from hemorrhagic shock with Ringer's ethyl pyruvate solution improves survival and ameliorates intestinal mucosal hyperpermeability in rats. Shock 2002:17: 473-7 DOI ScienceOn |
25 | Verhasselt V, Vanden Berghe W, Vanderheyde N, Willems F, Haegeman G, Goldman M. N-acetyl- L-cysteine inhibits primary human T cell responses at the dendritic cell level: association with NF-kappaB inhibition. J Immunol 1999:162:2569-74 |
26 | Pugin J, Verghese G, Widmer MC, Matthay MA. The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome. Crit Care Med 1999:27:304-12 DOI ScienceOn |
27 | Sibille Y, Reynolds HY. Macrophages and polymorphonuclear neutrophils in lung defense and injury. Am Rev Respir Dis 1990:141:471-501 DOI ScienceOn |
28 | Sims CA, Wattanasirichaigoon S, Menconi MJ, Ajami AM, Fink MP. Ringer's ethyl pyruvate solution ameliorates ischemia/reperfusion-induced intestinal mucosal injury in rats. Crit Care Med 2001:29:1513-8 DOI ScienceOn |
29 | Yang R, Gallo DJ, Baust JJ, Uchiyama T, Watkins SK, Delude RL, et al. Ethyl pyruvate modulates inflammatory gene expression in mice subjected to hemorrhagic shock. Am J Physiol Gastrointest Liver Physiol 2002:283:G212-21 DOI |
30 | Han Y, Englert JA, Yang R, Delude RL, Fink MP. Ethyl pyruvate inhibits nuclear factor-kappaBdependent signaling by directly targeting p65. J Pharmacol Exp Ther 2005:312:1097-105 DOI ScienceOn |
31 | Rahman I, Mulier B, Gilmour PS, Watchorn T, Donaldson K, Jeffery PK, et al. Oxidant-mediated lung epithelial cell tolerance: the role of intracellular glutathione and nuclear factor-kappaB. Biochem Pharmacol 2001:62:787-94 DOI ScienceOn |
32 | Melzer E, Schmidt HL. Carbon isotope effects on the decarboxylation of carboxylic acids: comparison of the lactate oxidase reaction and the degradation of pyruvate by H2O2. Biochem J 1988:252:913-5 DOI |