Significance of Corticosteroids and Their Relationship with Other Parameters in Patients with Sepsis
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Lee, Keu Sung
(Department of Pulmonary and Critical care Medicine, Ajou University, School of Medicine)
Baik, Seung Hee (Department of Pulmonary and Critical care Medicine, Ajou University, School of Medicine) Lee, Hyoung No (Department of Pulmonary and Critical care Medicine, Ajou University, School of Medicine) Park, Joo Hun (Department of Pulmonary and Critical care Medicine, Ajou University, School of Medicine) Oh, Yoon Jung (Department of Pulmonary and Critical care Medicine, Ajou University, School of Medicine) Sheen, Seung Soo (Department of Pulmonary and Critical care Medicine, Ajou University, School of Medicine) Choi, Young Hwa (Department of Pulmonary and Critical care Medicine, Ajou University, School of Medicine) Park, Kwang Joo (Department of Pulmonary and Critical care Medicine, Ajou University, School of Medicine) Hwang, Sung Chul (Department of Pulmonary and Critical care Medicine, Ajou University, School of Medicine) |
1 | Friedman G, Silva E, Vincent JL. Has the mortality of septic shock changed with time. Crit Care Med 1998:26:2078-86 DOI ScienceOn |
2 | Annane D, Sebille V, Charpentier C, Bollaert PE, Francois B, Korach JM, et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 2002:288:862-71 DOI ScienceOn |
3 | Chernow B, Alexander HR, Smallridge RC, Thompson WR, Cook D, Beardsley D, et al. Hormonal responses to graded surgical stress. Arch Intern Med 1987:147: 1273-8 DOI ScienceOn |
4 | Rothwell PM, Udwadia ZF, Lawler PG. Cortisol response to corticotropin and survival in septic shock. Lancet 1991:337:582-3 DOI ScienceOn |
5 | Moran JL, Chapman MJ, O'Fathartaigh MS, Peisach AR, Pannall PR, Leppard P. Hypocortisolaemia and adrenocortical responsiveness at onset of septic shock. Intensive Care Med 1994:20:489-95 DOI ScienceOn |
6 | Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Intensive Care Med 2003:29:530-8 DOI |
7 | Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med 1985:13:818-29 DOI ScienceOn |
8 | Annane D, Sebille V, Troche G, Raphael JC, Gajdos P, Bellissant E. A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin. JAMA 2000:283:1038-45 DOI ScienceOn |
9 | Loisa P, Rinne T, Kaukinen S. Adrenocortical function and multiple organ failure in severe sepsis. Acta Anaesthesiol Scand 2002:46:145-51 DOI ScienceOn |
10 | Smith I, Kumar P, Molloy S, Rhodes A, Newman PJ, Grounds RM, et al. Base excess and lactate as prognostic indicators for patients admitted to intensive care. Intensive Care Med 2001:27:74-83 DOI ScienceOn |
11 | Voerman HJ, Strack van Schijndel RJ, Groeneveld AB, de Boer H, Nauta JP, Thijs LG. Pulsatile hormone secretion during severe sepsis: accuracy of different blood sampling regimens. Metabolism 1992:41:934-40 DOI ScienceOn |
12 | Sharshar T, Blanchard A, Paillard M, Raphael JC, Gajdos P, Annane D. Circulating vasopressin levels in septic shock. Crit Care Med 2003:31:1752-8 DOI ScienceOn |
13 | Prigent H, Maxime V, Annane D. Clinical review: corticotherapy in sepsis. Crit Care 2004:8:122-9 DOI ScienceOn |
14 | Esteban NV, Loughlin T, Yergey AL, Zawadzki JK, Booth JD, Winterer JC, et al. Daily cortisol production rate in man determined by stable isotope dilution/mass spectrometry. J Clin Endocrinol Metab 1991:72:39-45 DOI |
15 | Ho JT, Al-Musalhi H, Chapman MJ, Quach T, Thomas PD, Bagley CJ, et al. Septic shock and sepsis: a comparison of total and free plasma cortisol levels. J Clin Endocrinol Metab 2006:91:105-14 DOI ScienceOn |
16 | Prigent H, Maxime V, Annane D. Science review: mechanisms of impaired adrenal function in sepsis and molecular actions of glucocorticoids. Crit Care 2004:8:243-52 DOI ScienceOn |
17 | Tordjman K, Jaffe A, Trostanetsky Y, Greenman Y, Limor R, Stern N. Low-dose (1 microgram) adrenocorticotrophin (ACTH) stimulation as a screening test for impaired hypothalamo-pituitary- adrenal axis function: sensitivity, specificity and accuracy in comparison with the high-dose (250 microgram) test. Clin Endocrinol 2000:52:633-40 DOI ScienceOn |
18 | Sam S, Corbridge TC, Mokhlesi B, Comellas AP, Molitch ME. Cortisol levels and mortality in severe sepsis. Clin Endocrinol 2004:60:29-35 DOI ScienceOn |
19 | McKee JI, Finlay WE. Cortisol replacement in severely stressed patients. Lancet 1983:1:484 |
20 | Jarek MJ, Legare EJ, McDermott MT, Merenich JA, Kollef MH. Endocrine profiles for outcome prediction from the intensive care unit. Crit Care Med 1993:21:543-50 DOI ScienceOn |
21 | Bernard G. The International Sepsis Forum's controversies in sepsis: corticosteroids should not be routinely used to treat septic shock. Crit Care 2002:6:384-6 DOI |
22 | Soni A, Pepper GM, Wyrwinski PM, Ramirez NE, Simon R, Pina T, et al. Adrenal insufficiency occurring during septic shock: incidence, outcome, and relationship to peripheral cytokine levels. Am J Med 1995:98:266-71 DOI ScienceOn |
23 | Lamberts SW, Bruining HA, de Jong FH. Corticosteroid thera7py in severe illness. N Engl J Med 1997:337:1285-924 DOI ScienceOn |
24 | Gonzalez H, Nardi O, Annane D. Relative adrenal failure in the ICU: an identifiable problem requiring treatment. Crit Care Clin 2006:22:105-18, vii DOI ScienceOn |
25 | Manglik S, Flores E, Lubarsky L, Fernandez F, Chhibber VL, Tayek JA. Glucocorticoid insufficiency in patients who present to the hospital with severe sepsis: a prospective clinical trial. Crit Care Med 2003:31:1668-75 DOI ScienceOn |
26 | Goodman S, Sprung CL, Ziegler D, Weiss YG. Cortisol changes among patients with septic shock and the relationship to ICU and hospital stay. Intensive Care Med 2005:31:1362-9 DOI ScienceOn |
27 | Venkatesh B, Mortimer RH, Couchman B, Hall J. Evaluation of random plasma cortisol and the low dose corticotropin test as indicators of adrenal secretory capacity in critically ill patients: a prospective study. Anaesth Intensive Care 2005: 33:201-9 |
28 | Yildiz O, Doganay M, Aygen B, Guven M, Keleutimur F, Tutuu A. Physiological-dose steroid therapy in sepsis (ISRCTN36253388). Crit Care 2002:6:251-9 DOI ScienceOn |
29 | Annane D, Sebille V, Bellissant E. Effect of low doses of corticosteroids in septic shock patients with or without early acute respiratory distress syndrome. Crit Care Med 2006:34:22-30 DOI ScienceOn |
30 | Rasmuson S, Olsson T, Hagg E. A low dose ACTH test to assess the function of the hypothalamicpituitary- adrenal axis. Clin Endocrinol 1996:44:151-6 DOI |
31 | Annane D, Bellissant E, Sebille V, Lesieur O, Mathieu B, Raphael JC, et al. Impaired pressor sensitivity to noradrenaline in septic shock patients with and without impaired adrenal function reserve. Br J Clin Pharmacol 1998:46:589-97 DOI ScienceOn |
32 | Hamrahian AH, Oseni TS, Arafah BM. Measurements of serum free cortisol in critically ill patients. N Engl J Med 2004:350:1629-38 DOI ScienceOn |
33 | Drucker D, Shandling M. Variable adrenocortical function in acute medical illness. Crit Care Med 1985:13:477-9 DOI ScienceOn |
34 | Loisa P, Uusaro A, Ruokonen E. A single adrenocorticotropic hormone stimulation test does not reveal adrenal insufficiency in septic shock. Anesth Analg 2005;101;1792-8 |
35 | El Azab SR, Rosseel PM, de Lange JJ, Groeneveld AB, van Strik R, van Wijk EM, et al. Dexamethasone decreases the pro- to anti-inflammatory cytokine ratio during cardiac surgery. Br J Anaesth 2002:88: 496-501 DOI ScienceOn |
36 | Burchard K. A review of the adrenal cortex and severe inflammation: quest of the 'eucorticoid' state. J Trauma 2001:51:800-14 DOI ScienceOn |
37 | Bouachour G, Tirot P, Gouello JP, Mathieu E, Vincent JF, Alquier P. Adrenocortical function during septic shock. Intensive Care Med 1995:21:57-62 DOI ScienceOn |
38 | Barton RN, Stoner HB, Watson SM. Relationships among plasma cortisol, adrenocorticotrophin, and severity of injury in recently injured patients. J Trauma 1987:27:384-92 DOI |
39 | Rothwell PM, Lawler PG. Prediction of outcome in intensive care patients using endocrine parameters. Crit Care Med 1995:23:78-83 DOI ScienceOn |
40 | Tsigos C, Chrousos GP. Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress. J Psychosom Res 2002:53:865-71 DOI ScienceOn |
41 | Oppert M, Schindler R, Husung C, Offermann K, Graf KJ, Boenisch O, et al. Low-dose hydrocortisone improves shock reversal and reduces cytokine levels in early hyperdynamic septic shock. Crit Care Med 2005:33:2457-64 DOI ScienceOn |
42 | Lundberg JS, Perl TM, Wiblin T, Costigan MD, Dawson J, Nettleman MD, et al. Septic shock: an analysis of outcomes for patients with onset on hospital wards versus intensive care units. Crit Care Med 1998:26:1020-4 DOI ScienceOn |
43 | Meduri GU, Chrousos GP. Duration of glucocorticoid treatment and outcome in sepsis: is the right drug used the wrong way- Chest 1998:114:355-60 |
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