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Exacerbation of Sarcoidosis Following Interferon-alpha Therapy for Chronic Active Hepatitis C  

Chang, Hye Jung (Department of Internal Medicine, Ewha Women University College of Medicine)
Choi, Eun Hwa (Department of Internal Medicine, Ewha Women University College of Medicine)
Kim, In Je (Department of Internal Medicine, Ewha Women University College of Medicine)
Sim, Yun Su (Department of Internal Medicine, Ewha Women University College of Medicine)
Lee, Jin Hwa (Department of Internal Medicine, Ewha Women University College of Medicine)
Kim, Tae Hun (Department of Internal Medicine, Ewha Women University College of Medicine)
Moon, Jin Wook (Department of Internal Medicine, Ewha Women University College of Medicine)
Chun, Eun Mi (Department of Internal Medicine, Ewha Women University College of Medicine)
Kim, Yoo Kyung (Department of Radiology, Ewha Women University College of Medicine)
Sung, Sun Hee (Department of Pathology, Ewha Women University College of Medicine)
Chang, Jung Hyun (Department of Internal Medicine, Ewha Women University College of Medicine)
Publication Information
Tuberculosis and Respiratory Diseases / v.61, no.3, 2006 , pp. 285-288 More about this Journal
Abstract
Interferon alpha is an immunomodulator that is used as an antiviral agent to treat chronic active viral hepatitis C. However, interferon can induce or exacerbate sarcoidosis. We report a case of 42-year-old man with an exacerbation of pulmonary sarcoidosis after the cessation of interferon and ribavirin therapy for chronic hepatitis C. The patient's sarcoidosis improved spontaneously and he continues to be monitored regularly without steroid therapy.
Keywords
Hepatitis C; Interferon; Sarcoidosis;
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