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A Case of Diffuse Alveolar Hemorrhage Complicated by HELLP (Hemolysis, Elevated Liver Enzymes, and Low Platelets) Syndrome  

Jeong, Woo Jin (Department of Internal Medicine, Division of Pulmonary & Critical Care Medicine, Asan Medical Center, Ulsan University College of Medicine)
Huh, Jin Won (Department of Internal Medicine, Division of Pulmonary & Critical Care Medicine, Asan Medical Center, Ulsan University College of Medicine)
Yu, Mi Hyun (Department of Internal Medicine, Division of Pulmonary & Critical Care Medicine, Asan Medical Center, Ulsan University College of Medicine)
Choi, Young Jun (Department of Internal Medicine, Division of Pulmonary & Critical Care Medicine, Asan Medical Center, Ulsan University College of Medicine)
Jeon, Min Hyok (Department of Internal Medicine, Division of Pulmonary & Critical Care Medicine, Asan Medical Center, Ulsan University College of Medicine)
Sim, Jae Yun (Department of Obstetrics and Gynecology, Asan Medical Center, Ulsan University College of Medicine)
Hong, Sang-Bum (Department of Internal Medicine, Division of Pulmonary & Critical Care Medicine, Asan Medical Center, Ulsan University College of Medicine)
Publication Information
Tuberculosis and Respiratory Diseases / v.59, no.4, 2005 , pp. 418-422 More about this Journal
Abstract
A diffuse alveolar hemorrhage (DAH) is a distinct form of pulmonary hemorrhage that originates from the pulmonary microcirculation. Disseminated intravascular coagulation (DIC) is one cause of DAH. Although HELLP syndrome associated with DIC can cause DAH, there are no published case reports that the authors are aware of. We report the case of a pregnant woman with HELLP syndrome who developed DAH. Because pregnant women with HELLP syndrome can develop DAH as a form of ARDS, a bronchoalveolar lavage may be used to make a differential diagnosis of this lung manifestation.
Keywords
Diffuse alveolar hemorrhage; HELLP syndrome; Disseminated intravascular coagulation;
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1 Sibai BM, Ramadan MK, Usta I, Salama M, Mercer BM, Friedman SA. Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets(HELLP syndrome). Am J Obstet Gynecol 1993;169:1000-6   DOI   ScienceOn
2 Van Dam PA, Renier M, Backland M, Buytaert P, Uyttenbroeck F. Disseminated intravascular coagulation and the syndrome of hemolysis, elevated liver enzymes, and low platelets in severe preeclampsia. Obstet Gynecol 1989;73:97-102
3 Robboy SJ, Minna JD, Colman RW, Birndorf NI, Lopas H. Pulmonary hemorrhage syndrome as a manifestation of disseminated intravascular coagulation: analysis of ten cases. Chest 1973;63:718-21   DOI   ScienceOn
4 Saka H, Ito T, Ito M, Watanabe A, Shimokata K. Diffuse pulmonary alveolar hemorrhage in acute promyelocytic leukemia. Intern Med 1992;31:457-8   DOI   ScienceOn
5 Weinstein L. Syndrome of hemolysis, elevated liver enzymes, and low platelet count: a severe consequence of hypertension. Am J Obstet Gynecol 1982;142:159- 67
6 Schhwarz MI, Cherniack RM, King JR. Diffuse alveolar hemorrhage and other rare infiltrative disorders. In: Murray, Nadel, editors. Textbook of respiratory medicine. 3rd ed. W.B. Saunders Company; 2000. p. 1733- 51
7 Collard HR, Schwarz MI. Diffuse alveolar hemorrhage. Clin Chest Med 2004;25:583-92   DOI   ScienceOn
8 Sibai BM. Diagnosis, contraversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count. Obstet Gynecol 2004;103:981- 91   DOI   ScienceOn
9 Nava S, Carbone G, DiBattista N, Bellone A, Baiardi P, Cosentini R, et al. Noninvasive ventilation in cardiogenic pulmonary edema. Am J Respir Crit Care Med 2003;168:1432–7   DOI   ScienceOn
10 Katsumura Y, Ohtsubo K. Incidence of pulmonary thromboembolism, infarction and haemorrhage in disseminated intravascular coagulation: a necroscopic analysis. Thorax 1995,50:160-4   DOI   ScienceOn
11 Silliman CC, Ambruso DR, Boshkov LK. Transfusionrelated acute lung injury. Blood 2005;105:2266-73   DOI   ScienceOn
12 Martin JN Jr, Files JC, Blake PG, Perry KG Jr, Morrison JC, Norman PH. Postpartum plasma exchange for atypical preeclampsia-ecclampsia as HELLP syndrome. Am J Obstet Gynecol 1995;172:1107-27   DOI   ScienceOn
13 Albelda SM, Gefter WB, Epstein DM, Miller WT. Diffuse pulmonary hemorrhage: a review and classification. Radiology 1985;154:289-97
14 The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000;342:1301-8   DOI   PUBMED   ScienceOn
15 Martin JN Jr, Thigsen BD, Rose CH, Cushman J, Moore A, May WL. Maternal benefit of high dose intravenous corticosteroid therapy for HELLP syndrome. Am J Obstet Gynecol 2003;189:830-4   DOI   PUBMED   ScienceOn