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A Case of Acromegaly Associated with Lung and Gastric Cancer  

Kim, Jin Soo (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
Kil, Uk Hyun (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
Song, Do Seon (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
Yang, Hong Jun (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
Lee, Hyeug (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
Huh, Min (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
Kim, Jeong Pyo (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
Kwon, Soon Seog (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
Kim, Young Kyoon (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
Kim, Kwan Hyoung (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
Moon, Hwa Sik (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
Song, Jeong Sup (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
Park, Sung Hak (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
Ahn, Joong Hyun (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
Publication Information
Tuberculosis and Respiratory Diseases / v.59, no.2, 2005 , pp. 198-203 More about this Journal
Abstract
Patients with acromegaly have high incidence of benign or malignant neoplasia than general population. Around fifteen percent of the deaths reported in acromegaly are attributable to malignancy of cancer. On the whole, mortality in acromegaly has been shown to be correlated with the degree of growth hormone (GH) control. Especially, the levels of insulin like growth factor-1 (IGF-1) may be higher in neoplasm, but there is no clear evidence to prove that tumor development is triggered by IGF-1 in acromegaly. Henceforth, we report a case of acromegaly associated with lung and gastric cancer in a 58-year-old man, suggesting the possible carcinogenic role of IGF-1.
Keywords
Acromegaly; Lung cancer; Gastric cancer;
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