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Progressive Lung Involvement during Steroid Therapy in Idiopathic Hypereosinophilic Syndrome  

Park, Ji Young (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Choi, Ju Young (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Jung, Ji Min (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Sim, Yun Su (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Pyun, Gun Woo (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Na, Youn Ju (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Kang, Min Jung (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Kang, In Sook (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Lee, Si Nae (Department of Pathology, College of Medicine, Ewha Womans University)
Kim, Yookyung (Department of Diagnostic Radiology of Medicine, College of Medicine, Ewha Womans University)
Jeong, Jee-Hyong (Department of Neurology, College of Medicine, Ewha Womans University)
Lee, Jin Hwa (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Cheon, Eun Mee (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Chang, Jung Hyun (Department of Internal Medicine, College of Medicine, Ewha Womans University)
Publication Information
Tuberculosis and Respiratory Diseases / v.59, no.1, 2005 , pp. 97-103 More about this Journal
Abstract
Hypereosinophilic syndrome (HES) is characterized by a sustained eosinophilia of $1,500/mm^3$ or more in the absence of any known causes or the signs and symptoms of organ involvement. We report a 64-year-old man with HES initially presenting with involvement of the liver and bone marrow. Despite controlling the eosinophilia by corticosteroid, he developed a cerebral infarction and later progressive interstitial pneumonia. Brain angiography revealed a severe stenosis of the proximal right internal carotid artery (ICA) and a complete obstruction of the intracranial ICA. An open lung biopsy revealed fibrosis and lymphoplasma cell infiltration without eosinophils, which were consistent with nonspecific interstitial pneumonia.
Keywords
Idiopathic hypereosinphilic syndrome;
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1 Weller PF, Bubley GJ. The idiopathic hypereosinophilic syndrome. Blood 1994;83:2759-79
2 Kim SS, Kim PS, Lee HB, Ryu JS, Seo JK, Choi SW. A case of idiopathic hypereosinophilic syndrome with segmental pulmonary involvement. J Asthma Allergy Clin Immunol 1998;18:733-40
3 Jee HS, An CH, Lee BH, Yu JH, Choi JS, Shin JW, et al. A case of hypereosinophilic syndrome with eosinophilic pneumonia, and bronchitis. J Asthma Allergy Clin Immunol 2001;21:662-7
4 Roh GS, Seo SW, Yeo SK, Lee JM, Choi JW, Kim EK, et al. Efficacy of a traditional Korean medicine, Chung-Sang-Bo-Ha-Tang, in a murine model of chronic asthma. Int Immunopharmcol 2005;5:427-36   DOI   ScienceOn
5 Lim JH, Lee WJ, Lee DH, Nam KJ. Hypereosinophilic syndrome: CT findings in patients with hepatic lobar or segmental involvement. Korean J Radiol 2000;1:98-103   DOI   ScienceOn
6 Hardy WR, Anderson RE. The hypereosinophilic syndrome. Ann Intern Med 1968;68:1220-9   DOI   ScienceOn
7 Yoon SS, Chang DI, Chung KC, Suh JT, Koo HS. Neurologic manifestations in patients with hypereosinophilia. J Korean Neurol Assoc 1995;13:623-30
8 Chusid MJ, Dale DC, West BC, Wolff SM. The hypereosinophilic syndrome: analysis of fourteen cases with review of the literature. Medicine 1975;54:1-27   DOI   ScienceOn
9 Fauci AS, Harley JB, Roberts WC, Ferrans VJ, Gralnick HR, Bjornson BH. The idiopathic hypereosinophilic syndrome: clinical, pathophysiologic, and therapeutic consideration. Ann Intern Med 1982;97:78-92   DOI   ScienceOn
10 Park JH, Lim KK, Choi CC, Kim HK, Kim IS. A case of idiopathic hypereosinophilic syndrome. Korean J Med 1987;32:416-21