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The Relationship between FEV1 and PEFR in the Classification of the Severity in COPD Patients  

Shin, Sang Youl (Department of Internal Medicine, College of Medicine, Konkuk University, Konkuk University Hospital)
Ho, Yoon Jae (Department of Internal Medicine, College of Medicine, Konkuk University, Konkuk University Hospital)
Kim, Sun Jong (Department of Internal Medicine, College of Medicine, Konkuk University, Konkuk University Hospital)
Yoo, Kwang Ha (Department of Internal Medicine, College of Medicine, Konkuk University, Konkuk University Hospital)
Publication Information
Tuberculosis and Respiratory Diseases / v.58, no.5, 2005 , pp. 507-514 More about this Journal
Abstract
Background : Measurement of the $FEV_1$ and PEFR in COPD patients is a significant indicator of the disease severity, the response to treatment and the acute exacerbation. However, it is not known if PEFR can be used to determine the severity of COPD because the agreement between PEFR and $FEV_1$ in COPD patients is not well known. Methods : From September, 2003 to August, 2004, 125 out patients with COPD who were treated at the pulmonary clinic in KonKuk University Hospital were enrolled in this study. The $FEV_1$ and PEFR of each patient were measured and all the data was analyzed using SPSS. Results : The average predicted $FEV_1$ % and PEFR % was $56.98{\pm}18.21%$ and $70{\pm}27.60%$, respectively. There was linear correlation between the predicted $FEV_1$ % and predicted PEFR %. There was no correlation between age of the COPD patients and the predicted PEFR %. There was correlation between dyspnea, which is a subjective symptom of the patients, and the predicted PEFR %. Conclusion : In COPD patients, the classification of the severity by PEFR tends to underestimate the state of the disease compared with the classification of the severity by the $FEV_1$. Therefore, the classification of the severity by PEFR should be interpreted carefully in patients with severe symptoms. Once the classification of the severity has made, the follow-up examination may use the PEFR instead of the $FEV_1$.
Keywords
Chronic obstructive pulmonary disease; $FEV_1$; Peak expiratory flow rate; Severity;
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