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A Case of Pulmonary Tuberculosis with Delayed Diagnosis Due to the Temporary Clinical Improvement After Use of Levofloxacin and Amikacin Under the Impression of Community Acquired Pneumonia  

Lee, Hee Seok (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, and Lung Institute, Seoul National University College of Medicine)
Kang, Young Ae (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, and Lung Institute, Seoul National University College of Medicine)
Oh, Jin Young (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, and Lung Institute, Seoul National University College of Medicine)
Lee, Jae Ho (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, and Lung Institute, Seoul National University College of Medicine)
Yoo, Chul Gyu (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, and Lung Institute, Seoul National University College of Medicine)
Lee, Choon-Taek (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, and Lung Institute, Seoul National University College of Medicine)
Kim, Young Whan (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, and Lung Institute, Seoul National University College of Medicine)
Han, Sung Koo (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, and Lung Institute, Seoul National University College of Medicine)
Shim, Young-Soo (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, and Lung Institute, Seoul National University College of Medicine)
Yim, Jae-Joon (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, and Lung Institute, Seoul National University College of Medicine)
Publication Information
Tuberculosis and Respiratory Diseases / v.55, no.4, 2003 , pp. 395-401 More about this Journal
Abstract
Fluoroquinolone is one of the first-line antibiotics recommended for treating community-acquired pneumonia. However, using fluroquinolones for presumptive community-acquired pneumonia can delay the diagnosis and the treatment of pulmonary tuberculosis because of its strong activity against mycobacteria. Here, we report a case of a 54-year-old female taking immunosuppressants after a renal transplant whose diagnosis of pulmonary tuberculosis was delayed as a result of the use of levofloxacin and amikacin under the original impression of community-acquired pneumonia. This case suggests that clinicians should consider the possibility of pulmonary tuberculosis in the case of a partial response of the pneumonia to flouroquinolones and/or aminoglycosides.
Keywords
Levofloxacin; Amikacin; Pulmonary tuberculosis; Pneumonia; Relayed diagnosis;
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