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http://dx.doi.org/10.5125/jkaoms.2017.43.3.147

The effectiveness of elective neck dissection on early (stage I, II) squamous cell carcinoma of the oral tongue  

Sung, Ki-Woong (Oral Cancer Center, Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University)
Kim, Soung Min (Oral Cancer Center, Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University)
Myoung, Hoon (Oral Cancer Center, Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University)
Kim, Myung-Jin (Oral Cancer Center, Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University)
Lee, Jong-Ho (Oral Cancer Center, Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University)
Publication Information
Journal of the Korean Association of Oral and Maxillofacial Surgeons / v.43, no.3, 2017 , pp. 147-151 More about this Journal
Abstract
Objectives: The purpose of this study was to evaluate and compare the treatment outcomes of partial glossectomy with or without elective neck dissection in patients with tongue squamous cell carcinoma (SCCa). Materials and Methods: A total of 98 patients who were diagnosed with tongue SCCa and underwent partial glossectomy between 2005 and 2014 were evaluated. Only 14 patients received elective neck dissection, and 84 patients received only partial glossectomy. Results: There were 56 men and 42 women with a mean age of 57 years and mean follow-up period of 33.7 months. There were 70 patients graded as T1 and 28 as T2. The total occult metastasis rate was 17.3%. The 5-year overall survival rate was 83.3% with elective neck dissection and 92.4% with observation. The 5-year disease-free survival rate was in 70.7% in the elective neck dissection group and 65.3% in the observation group. Conclusion: We retrospectively reviewed the records of 98 patients with tongue SCCa. These patients were divided into two groups, those who underwent elective neck dissection and those who did not. There was no statistically significant difference between the groups undergoing partial glossectomy with or without elective neck dissection.
Keywords
Occult neck metastasis; Elective neck dissection; N0 neck; Squamous cell carcinoma of the tongue;
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1 Liu TR, Chen FJ, Yang AK, Zhang GP, Song M, Liu WW, et al. Elective neck dissection in clinical stage I squamous cell carcinoma of the tongue: does it improve regional control or survival time? Oral Oncol 2011;47:136-41.   DOI
2 Landis SH, Murray T, Bolden S, Wingo PA. Cancer statistics, 1999. CA Cancer J Clin 1999;49:8-31, 1.   DOI
3 Bagan J, Sarrion G, Jimenez Y. Oral cancer: clinical features. Oral Oncol 2010;46:414-7.   DOI
4 Ow TJ, Myers JN. Current management of advanced resectable oral cavity squamous cell carcinoma. Clin Exp Otorhinolaryngol 2011;4:1-10.   DOI
5 Funk GF, Karnell LH, Robinson RA, Zhen WK, Trask DK, Hoffman HT. Presentation, treatment, and outcome of oral cavity cancer: a National Cancer Data Base report. Head Neck 2002;24:165-80.   DOI
6 Yuen AP, Lam KY, Chan AC, Wei WI, Lam LK, Ho WK, et al. Clinicopathological analysis of elective neck dissection for N0 neck of early oral tongue carcinoma. Am J Surg 1999;177:90-2.   DOI
7 Koo BS, Lim YC, Lee JS, Choi EC. Recurrence and salvage treatment of squamous cell carcinoma of the oral cavity. Oral Oncol 2006;42:789-94.   DOI
8 Argiris A, Karamouzis MV, Raben D, Ferris RL. Head and neck cancer. Lancet 2008;371:1695-709.   DOI
9 Sparano A, Weinstein G, Chalian A, Yodul M, Weber R. Multivariate predictors of occult neck metastasis in early oral tongue cancer. Otolaryngol Head Neck Surg 2004;131:472-6.   DOI
10 Akhtar S, Ikram M, Ghaffar S. Neck involvement in early carcinoma of tongue. Is elective neck dissection warranted? J Pak Med Assoc 2007;57:305-7.
11 Haddadin KJ, Soutar DS, Oliver RJ, Webster MH, Robertson AG, MacDonald DG. Improved survival for patients with clinically T1/T2, N0 tongue tumors undergoing a prophylactic neck dissection. Head Neck 1999;21:517-25.   DOI
12 Teichgraeber JF, Clairmont AA. The incidence of occult metastases for cancer of the oral tongue and floor of the mouth: treatment rationale. Head Neck Surg 1984;7:15-21.   DOI
13 Po Wing Yuen A, Lam KY, Lam LK, Ho CM, Wong A, Chow TL, et al. Prognostic factors of clinically stage I and II oral tongue carcinoma: a comparative study of stage, thickness, shape, growth pattern, invasive front malignancy grading, Martinez-Gimeno score, and pathologic features. Head Neck 2002;24:513-20.   DOI
14 Shah JP. Patterns of cervical lymph node metastasis from squamous carcinomas of the upper aerodigestive tract. Am J Surg 1990;160: 405-9.   DOI
15 Keski-Santti H, Atula T, Tornwall J, Koivunen P, Makitie A. Elective neck treatment versus observation in patients with T1/T2 N0 squamous cell carcinoma of oral tongue. Oral Oncol 2006;42:96-101.
16 Jalisi S. Management of the clinically negative neck in early squamous cell carcinoma of the oral cavity. Otolaryngol Clin North Am 2005;38:37-46, viii.   DOI
17 Yuen AP, Ho CM, Chow TL, Tang LC, Cheung WY, Ng RW, et al. Prospective randomized study of selective neck dissection versus observation for N0 neck of early tongue carcinoma. Head Neck 2009;31:765-72.   DOI
18 Lim YC, Lee JS, Koo BS, Kim SH, Kim YH, Choi EC. Treatment of contralateral N0 neck in early squamous cell carcinoma of the oral tongue: elective neck dissection versus observation. Laryngoscope 2006;116:461-5.   DOI
19 Werning JW, Heard D, Pagano C, Khuder S. Elective management of the clinically negative neck by otolaryngologists in patients with oral tongue cancer. Arch Otolaryngol Head Neck Surg 2003;129:83-8.   DOI
20 Persky MS, Lagmay VM. Treatment of the clinically negative neck in oral squamous cell carcinoma. Laryngoscope 1999;109:1160-4.   DOI
21 Kligerman J, Lima RA, Soares JR, Prado L, Dias FL, Freitas EQ, et al. Supraomohyoid neck dissection in the treatment of T1/T2 squamous cell carcinoma of oral cavity. Am J Surg 1994;168:391-4.   DOI