Browse > Article
http://dx.doi.org/10.5125/jkaoms.2016.42.2.111

Iron supplement tablet embedded in the oral cavity mimicking neoplasm: a case report  

Corliano, Fabrizio (Department of Otorhinolaryngology, University of Siena)
Falco, Paola (Department of Otorhinolaryngology, University of Siena)
Cambi, Jacopo (Department of Otorhinolaryngology, University of Siena)
Brindisi, Leopoldo (Department of Otorhinolaryngology, University of Siena)
Publication Information
Journal of the Korean Association of Oral and Maxillofacial Surgeons / v.42, no.2, 2016 , pp. 111-114 More about this Journal
Abstract
The detection of foreign bodies in the upper-aerodigestive tract is a fairly frequent event and can occur in various areas and for various reasons. In rare cases, foreign bodies can simulate a neoplasia. We evaluated similar cases during emergency regimen with an oral cavity mucosal lesion, causing lockjaw, sore throat, dysphagia, and swelling of the submandibular and laterocervical region. Physical examination revealed an extensive mucosal ulceration in the floor of the mouth and the lateral surface of the tongue, comparable to oral cancer. During a second, more accurate assessment, a partially deteriorated iron supplement tablet was found embedded in a mucosal pocket. After removing the tablet, gradual normalization of the tissue was observed without any sequelae. This is one of the many reasons why it is advisable and useful in cases of oral lesions to collect a detailed medical history and to perform an accurate clinical evaluation, including inspection and palpation of the lesion, before proceeding to further diagnostic assessments, especially in elderly patients taking many medications. However unlikely, it is possible that difficulty in swallowing pills or tablets could generate tumorlike lesions.
Keywords
Mouth neoplasms; Iron deficiency anemia; Oral ulcer; Foreign bodies;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
연도 인용수 순위
1 Abraham SC, Yardley JH, Wu TT. Erosive injury to the upper gastrointestinal tract in patients receiving iron medication: an underrecognized entity. Am J Surg Pathol 1999;23:1241-7.   DOI
2 Clarke BE, Kim ST. Iron-induced bronchial injury. Histopathology 2002;41:472-3.
3 Evrard C, Coffin O, Kaladji C, Brun J, Benard Y, Doumert J. Massive hemoptysis ten days after bronchial extraction of an accidentally inhaled tablet of ferrous sulfate. Ann Chir 1991;45:726-8.
4 Godden DJ, Kerr KM, Watt SJ, Legge JS. Iron lung: bronchoscopic and pathological consequences of aspiration of ferrous sulphate. Thorax 1991;46:142-3.   DOI
5 Raos M, Kovac K, Dodig S. Bronchial impairment of main bronchus by aspiration of ferrous sulphate tablet. Lijec Vjesn 2004;126: 194-6.
6 Cimino-Mathews A, Broman JH, Westra WH, Illei PB. Iron pillinduced tumefactive mucosal injury of the hypopharynx. Am J Surg Pathol 2010;34:1720-2.
7 Arora BK, Ruprecht A. Foreign body in tongue. Oral Surg Oral Med Oral Pathol 1978;45:823-5.   DOI
8 Price C, Whitehead FI. Impression materials as foreign bodies. Br Dent J 1972;133:9-14.   DOI
9 Lin CJ, Su WF, Wang CH. A foreign body embedded in the mobile tongue masquerading as a neoplasm. Eur Arch Otorhinolaryngol 2003;260:277-9.
10 Sathish R, Suhas S, Gayathri G, Ravikumar G, Chandrashekar L, Omprakash TL. Embedded toothbrush foreign body in cheek: report of an unusual case. Eur Arch Paediatr Dent 2011;12:272-4.   DOI
11 McKinney RV Jr, Brady GL, Singh BB. Metallic foreign body embedded in the cheek for 20 years. J Am Dent Assoc 1981;102:331-3.   DOI
12 Seikaly H, Rassekh CH. Oropharyngeal cancer. In: Bailey BJ, Johnson JT, Newlands SD, eds. Head and neck surgery: otolaryngology. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2006:1674-90.
13 Kwon JI, Kim HW, Nam W, Cha IH, Kim HJ. Traumatic ulcerative granuloma misjudged as oral squamous cell carcinoma (SCC) on the buccal cheek: case report. J Korean Assoc Oral Maxillofac Surg 2010;36:217-20.   DOI
14 Aruoma OI, Halliwell B. Superoxide-dependent and ascorbatedependent formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Are lactoferrin and transferrin promoters of hydroxyl-radical generation? Biochem J 1987;241:273-8.   DOI
15 Khan S, Agwani K, Bhargava P, Kumar SP. Adenoid cystic carcinoma presenting as an ulcer on the floor of the mouth: a rare case report. J Korean Assoc Oral Maxillofac Surg 2014;40:253-7.   DOI