Browse > Article
http://dx.doi.org/10.5125/jkaoms.2011.37.3.176

Statistical evaluation of ameloblastoma on the relationship between radiological and clinical characteristics  

Park, Ji-Hoon (Department of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University)
Kim, Jin-Wook (Department of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University)
Kwon, Tae-Geon (Department of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University)
Kim, Chin-Soo (Department of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University)
Publication Information
Journal of the Korean Association of Oral and Maxillofacial Surgeons / v.37, no.3, 2011 , pp. 176-183 More about this Journal
Abstract
Introduction: Very high aggressiveness and recurrence are important clinical characteristics of ameloblastoma compared to the other benign tumors. Therefore, an accurate diagnosis and treatment plan is important. This study examined the association of the clinical findings and recurrence based on the radiological findings of ameloblastoma. In recurrent cases, these results are expected to help in the diagnosis and treatment of ameloblastoma to examine the relevance with the clinical characteristics and radiological features. Materials and Methods: For a clinical (gender, age) and radiological (location, internal pattern, size, perforation, border pattern, impacted tooth, root resorption) evaluation, this study examined 156 cases of 147 patients diagnosed with ameloblastoma, who had been treated and in most cases regularly checked at the department of oral and maxillofacial surgery, Kyungpook National University Hospital, between January 1993 and December 2009. For a recurrent rate evaluation, a more than 3 years follow-up period is needed. Accordingly, 116 patients diagnosed with ameloblastoma between January 1994 and December 2007 were investigated. Results: The recurrence rate in all cases was 6.1% but was 7.8% in cases with follow-up periods more than 3 years. The male-to-female ratio was 3:2, showing a slight male predilection. Ameloblastoma had a peak occurrence in the second decade of life followed by the fourth decade of life. The mandibular angle area is the most frequent site of ameloblastoma (50.8%) in the jaws. Six cases of unilocular (7.8%) and 3 cases of multilocular (7.7%) ameloblastomas recurred. Seven cases of smooth (10%) and 2 cases of irregular (4.3%) ameloblastomas recurred. No cases of ameloblastomas without perforation of the cortical bone (0%) and 9 cases with a perforation of cortical bone (11.1%) recurred. Four cases of the ameloblastomas with impacted teeth (11.4%) and 5 cases of ameloblastomas without impacted tooth (6.2%) recurred. Seven cases of ameloblastomas with root resorption (10.9%) and 2 cases of ameloblastomas without root resorption (3.8%) recurred. Conclusion: A multiple smooth margin, unilocular ameloblastoma with an impacted tooth, root resorption tends to recur more easily. Therefore, they need to be treated more carefully and require a a longer follow-up.
Keywords
Ameloblastoma; Recurrence; Radiologic findings;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
연도 인용수 순위
1 Sherman RS, Caumartin H. The roentgen appearance of adamantinoma of the mandible. Radiology 1955;65:361-7.   DOI
2 Dolan EA, Angellilo JC, Georgiade NG. Recurrent ameloblastoma in autogenous rib graft: report of a case. Oral Surg Oral Med Oral Pathol 1981;51:357-60.   DOI   ScienceOn
3 Muller H, Slootweg PJ. The ameloblastoma, the controversial approach to therapy. J Maxillofac Surg 1985;13:79-84.   DOI
4 Hayward JR. Recurrent ameloblastoma 30 years after surgical treatment. J Oral Surg 1973;31:368-70.
5 Gardner DG. Peripheral ameloblastoma: a study of 21 cases, including 5 reported as basal cell carcinoma of the gingiva. Cancer 1977;39:1625-33.   DOI   ScienceOn
6 Park H, Jeong HG, Kim KD, Park CS. A radiologic study of ameloblastoma using computed tomography. Korean J Oral Maxillofac Radiol 2005;35:77-82.
7 Stafne EC. Value of roentgenograms in diagnosis of tumors of the jaws. Oral Surg Oral Med Oral Pathol 1953;6:82-92.   DOI   ScienceOn
8 Adekeye EO. Ameloblastoma of the jaws: a survey of 109 Nigerian patients. J Oral Surg 1980;38:36-41.
9 Sehdev MK, Huvos AG, Strong EW, Gerold FP, Willis GW. Proceedings: Ameloblastoma of maxilla and mandible. Cancer 1974;33:324-33.   DOI   ScienceOn
10 Robinston L, Martinez MG. Unicystic ameloblastoma: a prognostically distinct entity. Cancer 1977;40:2278-85.   DOI   ScienceOn
11 Gardner DG, Corio RL. The relationship of plexiform unicystic ameloblastoma to conventional ameloblastoma. Oral Surg Oral Med Oral Pathol 1983;56:54-60.   DOI   ScienceOn
12 Sirichitra V, Dhiravarangkura P. Intrabony ameloblastoma of the jaws: an analysis of 147 Thai patients. Int J Oral Surg 1984;13:187-93.   DOI
13 Tsaknis PJ, Nelson JF. The maxillary ameloblastoma: an analysis of 24 cases. J Oral Surg 1980;38:336-42.
14 Smith JF. Ameloblastoma : Report of thirty cases. Oral Surg 1960;13:1253-7.   DOI
15 Shteyer A, Lustman J, Lewin-Epstein J. The mural ameloblastoma: a review of the literature. J Oral Surg 1978;36:866-72.
16 Gardner DG. A pathologist's approach to the treatment of ameloblastoma. J Oral Maxillofac Surg 1984;42:161-6.   DOI
17 Robinson HBG. Ameloblastoma; a survey of 379 cases from the literature. Arch Pathol 1937;23:831-45.
18 Gardner DG, Corio RL. Plexiform unicystic ameloblastoma; a variant of ameloblastoma with a low recurrence after enucleation. Cancer 1984;53:1730-5.   DOI   ScienceOn
19 Hendler BH, Abaza NA, Moon AC, Herrod NW. Case 33, part 2. Ameloblastoma of the mandible. J Oral Surg 1981;39:208-13.
20 Mehlisch DR, Dahlin DC, Masson JK. Ameloblastoma: a clinicopathologic report. J Oral Surg 1972;30:9-22.
21 Kostic A, Jurisic A. X-ray diagnosis of ameloblastoma. Dentomaxillofac Radilol 1972;1:47-50.   DOI
22 Small IA, Waldron CA. Ameloblastoma of the jaws. Oral Surg Oral Med Oral Pathol 1955;8:281-97.   DOI   ScienceOn
23 Gardner DG. Plexiform unicystic ameloblastoma; a diagnostic problem in dentigerous cyst. Cancer 1981;47:1358-63.   DOI   ScienceOn
24 Gardner DG, Pecak AM. The treatment of ameloblastoma based on pathologic and anatomic principles. Cancer 1980;46:2514-19.   DOI   ScienceOn
25 Struthers P, Shear M. Root resorption by ameloblastomas and cysts of the jaws. Int J Oral Surg 1976;5:128-32.   DOI
26 Park TW. The incidence and classification of ameloblastoma. Korean J Oral Maxillofac Radiol 1985;15:21-6 .
27 Eversole LR, Leider AS, Strub D. Radiographic characteristics of cystogenic ameloblastoma. Oral Surg Oral Med Oral Pathol 1984;57:572-7.   DOI   ScienceOn
28 Lucas RB. Pathology of tumours of the oral tissues. 4th ed. New York: Churchill Livingstone; 1984:31-60.
29 Choi HB, You DS. A study of ameloblastoma on the relationship between histopathologic patterns and radiographic characteristics. Korean J Oral Maxillofac Radiol 1992;22:339-50.
30 Park NB, Shin SW, Kim CS. Clinico-statical study on the radiographic findings by the clinical findings of 115 ameloblastomas. J Korean Assoc Maxillofac Plast Reconstr Surg 1995;17:415-28.
31 Churchill, HR. Histological differentiation between certain dentigerous cysts and ameloblastoma. Dent Cosmos 1934;76:1173-8.
32 Mansson JK, McDonald JR, Figi FA. Adamantinoma of the jaws; a clinicopathologic study of 100 histologically proved cases. Plast Reconstr Surg Transplant Bull 1959;23:510-25.   DOI
33 Gorlin RJ, Chaudhry AP, Pindborg JJ. Odontogenic tumors. Classification, histopathologiy and clinical behavior in man and domasticated animals. Cancer 1961;14:73-101.   DOI   ScienceOn
34 Shafer WG, Hine MK, Levy BM. A textbook of oral pathology. 4th ed. Philadelphia: WB Saunders; 1983: 276-85.