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http://dx.doi.org/10.5125/jkaoms.2010.36.6.508

Clinical feature and treatment of bisphosphonate-related osteonecrosis of jaw about oral bisphosphonate administrated patients: case reports  

Choi, Woo-Sung (Department of Oral and Maxillofacial Surgery, Yeouido St. Mary's Hospital, The Catholic University of Korea)
Yoon, Hyun-Joong (Department of Oral and Maxillofacial Surgery, Yeouido St. Mary's Hospital, The Catholic University of Korea)
Lee, Sang-Hwa (Department of Oral and Maxillofacial Surgery, Yeouido St. Mary's Hospital, The Catholic University of Korea)
Publication Information
Journal of the Korean Association of Oral and Maxillofacial Surgeons / v.36, no.6, 2010 , pp. 508-514 More about this Journal
Abstract
Bisphosphonates are used effectively for many medical conditions, such as multiple myeloma, Paget's disease, osteoporosis, etc. However, recently, osteonecrosis of the jaw was observed in patients receiving long-term bisphosphonate therapy, including oral administration. This osteonecrosis is refractory, and complete recovery is not guaranteed despite a standard treatment protocol being established by many associations related to oral and maxillofacial surgery. The treatment outcome of oral bisphosphonate-related osteonecrosis of jaw (BRONJ) is reported with a review of the relevant literature.
Keywords
Bisphosphonate; Osteonecrosis; Osteoporosis;
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