Browse > Article

EXPRESSION OF ESTROGEN RECEPTORS IN RETRODISCAL TISSUE OF THE TEMPOROMANDIBULAR JOINT DISORDER PATIENTS  

Kim, Jong-Yun (Department of Oral and Maxillofacial Surgery, Gangnam Severance Hospital, Yonsei University)
Lim, Jae-Hyung (Department of Oral and Maxillofacial Surgery, Gangnam Severance Hospital, Yonsei University)
Park, Kwang-Ho (Department of Oral and Maxillofacial Surgery, Gangnam Severance Hospital, Yonsei University)
Kim, Hyung-Gon (Department of Oral and Maxillofacial Surgery, Gangnam Severance Hospital, Yonsei University)
Huh, Jong-Ki (Department of Oral and Maxillofacial Surgery, Gangnam Severance Hospital, Yonsei University)
Publication Information
Journal of the Korean Association of Oral and Maxillofacial Surgeons / v.35, no.6, 2009 , pp. 403-410 More about this Journal
Abstract
Those composing temporomandibular joint (TMJ) complex such as the temporal bone, the disc and the mandibular condyle perform their own functions with organic relation. The retrodiscal tissue is the main area of pain induction and contributes to compositional change of synovial fluid. If displacement of the disc lasts long time, not only adaptive changes, but also destructive or degenerative changes may happen. It was reported that these changes and symptoms appear mostly to female rather than male and especially, in the case of patients suffering from TMJ disorder, a large quantity of female sex hormone is found in the joint synovium. And that may play a role in bone resorption and inflammation. Also, the frequency and the intensity of pain perception for female is reported to be much more than for male. In this study, we investigated the expression extents of estrogen receptors (ER) and progesteron receptors (PR) in retrodiscal tissue with immunohistochemistry among the patients received TMJ surgery and compared with MRI findings and surgical findings. We report the relations between the expression of ER in retrodiscal tissue and the pathological change in TMJ, such as inflammation, internal derangement and osteoarthritis.
Keywords
Sex hormones; Estrogen receptors; Temporomandibular joint; Immunohistochemistry;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Huh JK, Park KK, Choi MA, Kim HG. Expression of matrix metalloproteinase-1 and -2 mRNA in retrodiscal tissue of the temporomandibular joint. J Kor Oral Maxillofac Surg 2003;29:212-8
2 Dworkin SF, LeResche L. Research diagnostic criteria for temporomandibular disorders: review, criteria, examinations and specifications, critique. J Craniomandib Disord 1992;6:301-55   PUBMED
3 Stegenga B. Osteoarthritis of the temporomandibular joint organ and its relationship to disc displacement. J Orofac Pain 2001;15:193-205   PUBMED
4 LeResche L, Saunders K, Von Korff MR, Barrlow W, Dworking SF. Use of exogenous hormones and risk of temporomandibular disorder pain. 1997;69:153-60   DOI   PUBMED   ScienceOn
5 Milam SB, Aufdemorte TB, Sheridan PJ, Triplett RG, Van Sickels JE, Holt GR. Sexual dimorphism in the distribution of estrogen receptors in the temporomandibular joint complex of the baboon. Oral Surg Oral Med Pathol 1987;64:527-32   DOI   PUBMED   ScienceOn
6 Takahashi T, Nagai H, Seki H, Fukuda M. Relationship between joint effusion, joint pain, and protein levels in joint lavage fluid of patients with internal derangement and osteoarthritis of the temporomandibular joint. J Oral Maxillofac Surg 1999;57:1187-93   DOI   PUBMED   ScienceOn
7 Kapila S, Xie Y. Targeted induction of collagenase and stromelysin by relaxin in unprimed and beta-estradiol-primed diarthrodial joint fibrocartilaginous cells but not on synoviocytes. Lab Invest 1998;78:925-38
8 Abubaker AO, Raslan WF, Sotereanos GC. Estrogen and progesterone receptors in temporomandibular joint discs of symptomatic and asymptomatic persons: A preliminary study. J Oral Maxillofac Surg 1993;51:1096-100   DOI   PUBMED   ScienceOn
9 Huh JK, Kim HG. Relationship between histologic features of the retrodiskal tissues and magnetic resonance imaging findings in temporomandibular joint internal derangement. J Kor Oral Maxillofac Surg 2000;25:378-82
10 Corvol M, O Blanchard, L Tsagris. Bone and cartilage responsiveness to sex steroid hormones. J Steroid Biochem Mol Biol 1992;43:415-8   DOI   PUBMED   ScienceOn
11 Wilkinson TM, Crowley CM. A histologic study of retrodiscal tissues of the human temporomandibular joint in the open and closed position. J Orofac Pain 1994;8:7-17   PUBMED
12 Stegenga B, de Bont LGM, Boering G. Osteoarthritis as the cause of craniomandibular pain and dysfunction: A unifying concept. J Oral Maxillofac Surg 1989;47:249-56   DOI   PUBMED   ScienceOn
13 Flake NM, Hermanstyne TO, Gold MS. Testosterone and estrogen have opposing actions on inflammation-induced plasma extravasation in the rat temporomandibular joint. Am J Physiol Regul Integr Comp Physiol 2006;291:343-8   DOI   PUBMED   ScienceOn
14 Arnett GW, Milan SB, Gottesman L. Progressive mandibular retrusion-idiopathic condylar resorption. Part I Am J Orthod Dentofacial Orthop 1996;10:8-15   DOI   PUBMED   ScienceOn
15 Kullila M, PM Niemi, S Kuttila, P Alanen, Y Le Bell. TMD treatment need in relation to age, gender, stress, and diagnostic subgroup. J Orofac Pain 1998;12:67-74   PUBMED
16 Ko JY, Kim KD, Park CS. Magnetic resonance evidence of joint effusion in patients with temporomandibular joint disorders. Korean J Oral Maxillofac Radiol 2001;31:73-84
17 Kaplan PA, Helms CA. Current status of temporomandibular joint imaging for the diagnosis of internal derangements. AJR Am J Roentgenol 1989;152:697-705   DOI   PUBMED   ScienceOn
18 Stegenga B. Osteoarthritis of the temporomandibular joint organ and its relationship to disc displacement. J Orofac Pain 2001;15:193-205   PUBMED
19 Meisler JG. Chronic pain conditions in women. J Womens Health 1999;8:313-20   DOI   ScienceOn
20 McGuire WL, Horowitz KB, Pearson OH, Segaloff A. Current status of estrogen and progesterone receptors in breast cancer. Cancer 1977;32:2934-47   DOI   PUBMED   ScienceOn
21 Romanelli GG, Harper R, Mock D, Pharoah MJ, Tenenbaum HC. Evaluation of temporomandibular joint internal derangement. J Orofac Pain 1993;7:254-62
22 Kubota T, Kubota E, Matsumoto A, Kawai Y, Saito H, Mikuni-Takagaki Y, et al. Identification of matrix metalloproteinases (MMPs) in synovial fluid from patients with temporomandibular disorder. Eur J Oral Sci 1998;106:992-8   DOI   PUBMED   ScienceOn
23 Nitzan DW, Mahler Y, Simkin A. Intra-articular pressure measurements in patients with suddenly developing, severely limited mouth opening. J Oral Maxillofac Surg 1992;50:1038-43   DOI   PUBMED   ScienceOn
24 Gage JP. Collagen biosynthesis related to temporomandibular joint clicking in childhood. J Prosthet Dent 1985;53:714-7   DOI   PUBMED   ScienceOn
25 LeResche L. Epidermiology of temporomandibular disorders: Implications for the investigation of etiologic factors. Crit Rev Oral Biol Med 1997;8:291-305   DOI   PUBMED   ScienceOn
26 Isberg A, Isacsson G. Tissue reactions associated with internal derangement of the temporomandibular joint: A radiographic, crymorphologic, and histologic study. Acta Odontol Scand 1986;44:159-64   DOI   PUBMED
27 Ratcliffe A, Israel HA, Saed-Nejad F, Diamond B. Proteoglycans in the synovial fluid of the temporomandibular joint as an indicator of changes in cartilage metabolism during primary and secondary osteoarthritis. J Oral Maxillofac Surg 1998;56:204-8   DOI   PUBMED   ScienceOn
28 Landi N, Lombardi I, Manfredini D, Casarosa E, Biondi K, Gabbanini M, et al. Sexual hormone serum levels and temporomandibular disorders: A preliminary study. Gynecol Endocrinol 2005;20:99-103   DOI   PUBMED   ScienceOn
29 Stegenga B, de Bont LGM, Boering G, van Willigen JD. Tissue responses to degenerative changes in the temporomandibular joint. A review J Oral Maxillofac Surg 1991;49:1079-88   DOI   PUBMED   ScienceOn