Browse > Article

THE THERAPEUTIC EFFECT OF SILVER NANOCRYSTALLINE OINTMENT ON TMJ CAPSULITIS  

Chae, Chang-Hoon (Dept. of Dentistry, College of Medicine, Hallym University)
Kim, Jwa-Young (Dept. of Dentistry, College of Medicine, Hallym University)
Kim, Mi-Ja (Dept. of Dentistry, College of Medicine, Hallym University)
Chung, Hoon (Chung Hoon Private Dental Clinic)
Kim, Seung-Ho (Dept of Instrumental Analysis, KRIBB)
Oh, Hyun-Woo (Dept of Instrumental Analysis, KRIBB)
Kim, Young-Nam (NPC Co., Ltd)
Kim, Young-Il (NPC Co., Ltd)
Yang, Byung-Ho (Dept. of Dentistry, College of Medicine, Hallym University)
Kim, Seong-Gon (Dept. of Dentistry, College of Medicine, Hallym University)
Publication Information
Journal of the Korean Association of Oral and Maxillofacial Surgeons / v.32, no.3, 2006 , pp. 262-266 More about this Journal
Abstract
The silver nanocrystalline is widely used for biological field because of its biocompatibility and anti-microbial effect. The objective of this study was to evaluate the therapeutic efficacy of the silver nanocrystalline ointment on the temporomandibular joint (TMJ) capsulitis. Total 39 patients were included in this study and all patients were received single topical application of the silver nanocrystalline ointment (group A, n=30) or placebo ointment (group B, n=19). Measured variables were maximum mouth opening (MMO), visual analog scale (VAS) for pain, and VAS for function. In results, we could not assess any therapeutic efficacy of single application in the chronic TMJ capsulitis (p>0.05). However, the single application of silver nanocrystalline ointment showed significant improvement in MMO and VAS for pain compared to placebo effect in the acute TMJ capsulitis (p<0.05). We could not find any complications related to ointment application in both groups. In conclusion, the single application of silver nanocrystalline ointment was effective in improving patient's symptom in acute TMJ capsulitis without any noticing complications.
Keywords
Citations & Related Records
연도 인용수 순위
  • Reference
1 Pullinger AG, Seligman DA, Solberg WK: Temporomandibular disorders. Part I: Functional status, dentomorphologic features, and sex differences in a nonpatient population. J Prosthet Dent 1988;59:228-235   DOI   ScienceOn
2 Grosfeld O, Jackowska M, Czarnecka B: Results of epidemiological examinations of the temporomandibular joint in adolescents and young adults. J Oral Rehabil 1985;12:95-105   DOI
3 Choi YS, Choung PH, Moon HS, Kim SG: Temporomandibular disorders in 19-year-old Korean men. J Oral Maxillofac Surg 2002;60:797-803   DOI   ScienceOn
4 Tredget EE, Shankowsky HA, Groeneveld A, Burrell RE: A matched-pair, randomized study evaluation of the efficacy and safety of Acticoat_ silver coated dressing for the treatment of burn wounds. J Burn Care Rehabil 1998;19:531-537   DOI   ScienceOn
5 Walker M, Cochrane CA, Bowler PG, Parsons D, Bradshaw P: Silver deposition and tissue staining associated with wound dressings containing silver. Ostomy Wound Manage 2006;52:42-44, 46-50
6 Hamada Y, Kondoh T, Holmlund AB, Nakajima T, Horie A, Saito T, et al: One-year clinical course following visually guided irrigation for chronic closed lock of the temporomandibular joint. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:170-174   DOI   ScienceOn
7 Topoglidis E, Discher BM, Moser CC, Dutton PL, Durrant JR: Functionalizing nanocrystalline metal oxide electrodes with robust synthetic redox proteins. Chembiochem 2003;4:1332-1339   DOI   ScienceOn
8 Ethunandan M, Wilson AW: Temporomandibular Joint Arthrocentesis- More Questions Than Answers? J Oral Maxillofac Surg 2006;64:952-955   DOI   ScienceOn
9 Kim SJ, Park YH, Hong SP, Cho BO, Park JW, Kim SG: The presence of bacteria in the synovial fluid of the temporomandibular joint and clinical significance: Preliminary study. J Oral Maxillofac Surg 2003;61:1156-1161   DOI   ScienceOn
10 Bhol KC, Schechter PJ: Topical nanocrystalline silver cream suppresses inflammatory cytokines and induces apoptosis of inflammatory cells in a murine model of allergic contact dermatitis. Br J Dermatol 2005;152:1235-1242   DOI   ScienceOn
11 Wright JB, Lam K, Burrell RE: Wound management in an era of increasing bacterial antibiotic resistance: a role for topical silver treatment. Am J Infect Control 1998;26:572-577   DOI   ScienceOn
12 Jeon YD, Lee JI, Cho BO, Rotaru H, Kim JC, Kim SG: The relation of head and neck infections and the temporomandibular joint disease. Oral Surg Oral Med Oral Pathol Oral Radiol Endodon 2005;99:677-681   DOI   ScienceOn
13 Haes AJ, Van Duyne RP: A nanoscale optical biosensor: sensitivity and selectivity of an approach based on the localized surface plasmon resonance spectroscopy of triangular silver nanoparticles. J Am Chem Soc 2002:124;10596-10604   DOI   ScienceOn
14 Alivisatos AP: Biomineralization. Naturally aligned nanocrystals. Science 2000;289:736-737   DOI   ScienceOn
15 Tutar E, Atalay S, Yilmaz E, Ucar T, Kocak G, Imamoglu A: Poststreptococcal reactive arthritis in children: is it really a different entity from rheumatic fever? Rheumatol Int 2002;22:80-83   DOI
16 Turner JL, Chen Z, Wooley KL: Regiochemical functionalization of a nanoscale cage-like structure: robust core-shell nanostructures crafted as vessels for selective uptake and release of small and large guests. J Control Release 2005;109:189-202   DOI   ScienceOn
17 Bruchez MJr, Moronne M, Gin P, Weiss S, Alivisatos AP: Semiconductor nanocrystals as fluorescent biological labels. Science 1998;281:2013-2015   DOI
18 Lok CN, Ho CM, Chen R, He QY, Yu WY, Sun H, et al: Proteomic analysis of the mode of antibacterial action of silver nanoparticles. J Proteome Res 2006;5:916-924   DOI   ScienceOn
19 Bhol KC, Alroy J, Schechter PJ: Anti-inflammatory effect of topical nanocrystalline silver cream on allergic contact dermatitis in a guinea pig model. Clin Exp Dermatol 2004;29:282-2879   DOI   ScienceOn
20 Jeon HS, Hong SP, Cho BO, Mulyukin A, Choi JY, Kim SG: Hematogenous infection of the human temporomandibular joint. Oral Surg Oral Med Oral Pathol Oral Radiol Endodon 2005;99:E11-17   DOI   ScienceOn
21 Kopp S, Alstergren P, Ernestam S, Nordahl S, Morin P, Bratt J: Reduction of temporomandibular joint pain after treatment with a combination of methotrexate and infliximab is associated with changes in synovial fluid and plasma cytokines in rheumatoid arthritis. Cells Tissues Organs 2005;180:22-30   DOI   ScienceOn
22 Vikram HR, Buencamino RB, Aronin SI: Primary meningococcal arthritis in a prosthetic knee joint. J Infect 2001;42:279-281   DOI   ScienceOn
23 Melaiye A, Sun Z, Hindi K, Milsted A, Ely D, Reneker DH, et al: Silver(I)-imidazole cyclophane gem-diol complexes encapsulated by electrospun tecophilic nanofibers: formation of nanosilver particles and antimicrobial activity. J Am Chem Soc 2005;127:2285-2291   DOI   ScienceOn
24 Catledge SA, Fries MD, Vohra YK, Lacefield WR, Lemons JE, Woodard S, et al: Nanostructured ceramics for biomedical implants. J Nanosci Nanotechnol 2002;2:293-312   DOI   ScienceOn
25 Ogura N, Tobe M, Sakamaki H, Nagura H, Abiko Y, Kondoh T: Tumor necrosis factor-alpha increases chemokine gene expression and production in synovial fibroblasts from human temporomandibular joint. J Oral Pathol Med 2005;34:357-363   DOI   ScienceOn
26 Dworkin SF, LeResche L: Research Diagnostic Criteria for Temporomandibular Disorders. J Craniomandib Disord Facial Oral Pain 1992;6:301-355