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http://dx.doi.org/10.14476/jomp.2015.40.2.79

Oral Hairy Leukoplakia in Patient with Human Immunodeficiency Virus Infection  

Park, Gunwoo (Department of Orofacial Pain and Oral Medicine, Dental Hospital, Yonsei University College of Dentisty)
Ahn, Hyung Joon (Department of Orofacial Pain and Oral Medicine, Dental Hospital, Yonsei University College of Dentisty)
Choi, Jong-Hoon (Department of Orofacial Pain and Oral Medicine, Dental Hospital, Yonsei University College of Dentisty)
Kwon, Jeong-Seung (Department of Orofacial Pain and Oral Medicine, Dental Hospital, Yonsei University College of Dentisty)
Publication Information
Journal of Oral Medicine and Pain / v.40, no.2, 2015 , pp. 79-81 More about this Journal
Abstract
Oral hairy leukoplakia occurs on the lateral surface of the tongue that clinically as an asymptomatic white lesion. It is mainly found in patient with human immunodeficiency virus infection. However, it rarely outbreak immunosuppressed patients after organ transplantation, or the patients taking steroids or immunosuppressants. It is the result of proliferating Epstein-Barr virus in the oral epithelium. Most of human immunodeficiency virus infected patients with oral hairy leukoplakia are highly contagious and possible to progress acquired immunodeficiency syndrome. Therefore, the early diagnosis of oral hairy leukoplakia is very important. Taking a thorough history and human immunodeficiency virus screening test is highly recommended in case oral hairy leukoplakia is detected. In this case, a 29-year-old man presented with whitish lesion on lateral border of tongue is diagnosed as oral hairy leukoplakia and human immunodeficiency virus infection.
Keywords
Acquired immunodeficiency syndrome; Herpesvirus-4, human; HIV; Leukoplakia, hairy;
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1 Greenspan D, Greenspan JS, Conant M, Petersen V, Silverman S Jr, de Souza Y. Oral “hairy” leucoplakia in male homosexuals: evidence of association with both papillomavirus and a herpes-group virus. Lancet 1984;2:831-834.
2 Mendoza N, Diamantis M, Arora A, et al. Mucocutaneous manifestations of Epstein-Barr virus infection. Am J Clin Dermatol 2008;9:295-305.   DOI   ScienceOn
3 Pedreira EN, Cardoso CL, Barroso Edo C, Santos JA, Fonseca FP, Taveira LA. Epidemiological and oral manifestations of HIVpositive patients in a specialized service in Brazil. J Appl Oral Sci 2008;16:369-375.   DOI
4 Greenspan JS, Greenspan D. Oral hairy leukoplakia: diagnosis and management. Oral Surg Oral Med Oral Pathol 1989;67:396-403.   DOI   ScienceOn
5 Bhandarkar SS, MacKelfresh J, Fried L, Arbiser JL. Targeted therapy of oral hairy leukoplakia with gentian violet. J Am Acad Dermatol 2008;58:711-712.   DOI   ScienceOn
6 Moura MD, Haddad JP, Senna MI, Ferreira e Ferreira E, Mesquita RA. A new topical treatment protocol for oral hairy leukoplakia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010;110:611-617.   DOI   ScienceOn
7 Moura MD, Guimaraes TR, Fonseca LM, de Almeida Pordeus I, Mesquita RA. A random clinical trial study to assess the efficiency of topical applications of podophyllin resin (25%) versus podophyllin resin (25%) together with acyclovir cream (5%) in the treatment of oral hairy leukoplakia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103:64-71.   DOI   ScienceOn
8 Galvin S, Healy CM. Oral hairy leukoplakia in healthy, immunocompetent individuals. Ir Med J 2014;107:179-180.
9 Reynolds SJ, Muwonga J. OraQuick ADVANCE rapid HIV-1/2 antibody test. Expert Rev Mol Diagn 2004;4:587-591.   DOI   ScienceOn
10 Zachary D, Mwenge L, Muyoyeta M, et al. Field comparison of OraQuick ADVANCE rapid HIV-1/2 antibody test and two blood-based rapid HIV antibody tests in Zambia. BMC Infect Dis 2012;12:183.   DOI
11 Delaney KP, Branson BM, Uniyal A, et al. Performance of an oral fluid rapid HIV-1/2 test: experience from four CDC studies. AIDS 2006;20:1655-1660.   DOI   ScienceOn
12 Wesolowski LG, MacKellar DA, Facente SN, et al; Post-marketing Surveillance Team. Post-marketing surveillance of OraQuick whole blood and oral fluid rapid HIV testing. AIDS 2006;20:1661-1666.   DOI   ScienceOn
13 Baccaglini L, Atkinson JC, Patton LL, Glick M, Ficarra G, Peterson DE. Management of oral lesions in HIV-positive patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103 Suppl:S50.e1-S50.e23.
14 Gowdey G, Lee RK, Carpenter WM. Treatment of HIV-related hairy leukoplakia with podophyllum resin 25% solution. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1995;79:64-67.   DOI   ScienceOn
15 Sanchez M, Spielman T, Epstein W, Moy J. Treatment of oral hairy leukoplakia with podophyllin. Arch Dermatol 1992;128:1659.   DOI
16 Brasileiro CB, Abreu MH, Mesquita RA. Critical review of topical management of oral hairy leukoplakia. World J Clin Cases 2014;2:253-256.   DOI