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Case Report of Squamous Cell Carcinoma arising in an Oral Lichen Planus and Literature Investigation  

Lim, Hyun-Dae (Department of Oral medicine, School of Dentistry, Wonkwang University)
Lee, You-Mee (Department of Oral medicine, School of Dentistry, Wonkwang University)
Publication Information
Journal of Oral Medicine and Pain / v.34, no.1, 2009 , pp. 49-54 More about this Journal
Abstract
Lichen planus is a relatively common chronic inflammatory disease involving the skin and mucous membranes showing small flat polygonal papules. The accurate etiology is unknown but it's suggested that cell-mediated immune response to an induced antigenic changes in skin or mucosa. Oral lichen planus was regarded as an benign lesion but oral lichen planus was classified as premalignant lesion by WHO criteria. It was not known that progress of malignat transmmission in the the patient with oral lichen planus, and chronic inflammatory disease including oral lichen planus showed malignacy in oral cancer unrelated common risk factors(Ex: tabacco, alcohol). Although malignant development in the patient with oral liche planus was various greatly in the literature, from 0.5% upward to 5%. It has been reported that a specific clinical type of oral lichen planus, hyperkeratotic or erosive had a higher chance of transformation into an squamous carcinoma. Clinician has to follow-up check of at least one or two visit per year to detect of malignancy of oral lichen planus and improved prognosis with squamous cell carcinoma. At this case with the middle aged women with squamous cell carcinoma developed from oral lichen planus of more than a decade of persisting, we try to discuss the malignacy of oral lichen planus and cosideration with follow-up.
Keywords
Oral lichen planus; Malignant transformation; Squamous cell carcinoma; Follow-up;
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