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Rational Diagnosis and Management of Sjogren's Syndrome  

Tae, Il-Ho (Department of Oral Diagnosis & Oral Medicine, Dental Hospital, Yonsei University, College of Dentistry)
Kwon, Jeong-Seung (Department of Oral Diagnosis & Oral Medicine, Dental Hospital, Yonsei University, College of Dentistry)
Jeon, Young-Mi (Department of Oral Diagnosis & Oral Medicine, Dental Hospital, Yonsei University, College of Dentistry)
Choi, Jong-Hoon (Department of Oral Diagnosis & Oral Medicine, Dental Hospital, Yonsei University, College of Dentistry)
Shim, Woo-Hyun (Department of Oral Diagnosis & Oral Medicine, Dental Hospital, Yonsei University, College of Dentistry)
Ahn, Hyung-Joon (Department of Oral Diagnosis & Oral Medicine, Dental Hospital, Yonsei University, College of Dentistry)
Publication Information
Journal of Oral Medicine and Pain / v.32, no.4, 2007 , pp. 397-402 More about this Journal
Abstract
Sjogren's syndrome is a chronic autoimmune disorder of the exocrine glands with associated lymphocytic infiltrates of the affected glands. Primary SS presents alone as xerostomia, keratoconjunctivitis sicca and patotid gland enlargement, secondary SS occurs in connection with other autoimmune disorder such as rheumatitoid arthritis, systemic lupus erythematosus, or progressive systemic sclerosis. Among many other systemic complication, lymphoma is considered seriously. Patient with SS had a 44 times higher relative risk of lymphoma, and clinically identifiable lymphoma occurs in approximately 5% of patients with SS. So, patients with SS should be closely monitored. In dental office, diagnosis of SS is important in view of high risk of lymphoma. When a dentist diagnose and manage dry mouth, he or she should consider possibility of SS all the times and have knowledge of diagnostic criteria of SS.
Keywords
Sjogren's syndrome; Diagnositic criteria; Lymphoma;
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