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http://dx.doi.org/10.5536/KJPS.2013.40.2.115

Effects of SNP in TSH-β Gene of Chicken on Economic Traits  

Seo, Joohee (Genomic Informatics Center, Hankyong National University)
Oh, Jae Don (Genomic Informatics Center, Hankyong National University)
Choi, Eun Ji (Genomic Informatics Center, Hankyong National University)
Lim, Hee Kyong (Genomic Informatics Center, Hankyong National University)
Seong, Jiyeon (Genomic Informatics Center, Hankyong National University)
Song, Ki Duk (Genomic Informatics Center, Hankyong National University)
Lee, Jun Heon (Department of Animal Science and Biotechnology, Chunam National University)
Lee, Hak Kyo (Genomic Informatics Center, Hankyong National University)
Kong, Hong Sik (Genomic Informatics Center, Hankyong National University)
Jeon, Gwang Joo (Genomic Informatics Center, Hankyong National University)
Shon, Young Gon (GRRC, Hankyong National University)
Choi, Kang Duk (Genomic Informatics Center, Hankyong National University)
Publication Information
Korean Journal of Poultry Science / v.40, no.2, 2013 , pp. 115-120 More about this Journal
Abstract
Thyroid hormone (TH) plays a role in growth of the poultry. Thyroid-stimulating hormone (TSH) stimulates production and distribution of TH, and is a heterodimer which is formed by ${\alpha}$- and ${\beta}$-subunits. Most of TSH activity is known to rely on ${\beta}$-subunit. TSH-${\beta}$ gene is located on chicken chromosome 26 and associated with growth performances. Therefore, this study aimed to investigate the association of TSH- ${\beta}$ SNP (G1031C) with economic traits (layday, layw, layno, bw150, bw270, layw270) in Korean Native Black chicken, Rhode Island Red and Cornish. Allele frequency of GG genotype in Rhode Island Red (RIR) was found to be 1.00 in this study. A significant effect was only observed on body weight at day 150 in Cornish. In Cornish, body weights of chicken with the CC genotype ($302.15{\pm}6.336$) were significantly higher than that of the GG genotype ($294.56{\pm}4.537$) (p<0.05). These findings suggest that the G1031C SNP of TSH-${\beta}$ gene can be used for improvement of growth-related traits in Cornish.
Keywords
thyroid-stimulating hormone-${\beta}$(TSH-${\beta}$); single nucleotide polymorphism; allele frequency; body weight; Cornish;
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