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http://dx.doi.org/10.5857/RCP.2016.5.1.11

Induction of Demyelination by Infection of Semliki Forest Virus

Kim, Hyun Joo (Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine)
Choi, Chang-Shik (Department of Food and Fermentation, Far East University)
Hong, Seong-Karp (Division of Bio and Health Sciences, Mokwon University)

Publication Information

Rapid Communication in Photoscience / v.5, no.1, 2016 , pp. 11-12 More about this Journal

Abstract

Schwann cells and neuronal cells from dorsal root ganglion (DRG) in embryos of rat were cultured in vitro respectively. The purified neuronal cells with anti-mitotic agents and purified Schwann cells were co-cultured and then accomplished myelination processing. Infection of Semliki forest virus into this myelinated co-culture system was performed and then accomplished demyelination. We identified myelination and demyelination processing using antibody of neuropeptide Y.

Keywords

demyelination; myelination neuropeptide Y; Semliki Forest virus;

Citations & Related Records

Reference

1	Mokhtarian, F.; Huan, C.; Roman, C.; Raine C. S. J Neuroimmunol 2003, 137, 19-31,. DOI
2	Liu, R.; Lin, G.;Xu, H. PLoS one 2013, 8,1-7,.
3	Fukuda, J. Develop. Neurosci. 1985, 7, 374-394,.
4	Fukuda, J.; Kameyama, M. Nature, 1979, 279, 546-548,. DOI
5	Unsicker, K.; Skaper, S. D.; Davis, G. E.; Manthorpe, M.; Varon, S. Developmental Brain Research 1985, 7, 304-308,.
6	Kim, H. A.; Maurel, P. Springer Protocols Handbooks, Humana Press, a part of Springer, Science+Business Media, 2001, 253-268,.