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http://dx.doi.org/10.7853/kjvs.2022.45.2.125

Analysis on antibody titer of structural protein after vaccination against foot-and-mouth disease virus (Type O) in zoo animals  

Lee, Hyun-Ho (Seoul Metropolitan Government Research Institute of Public Health ＆ Environment)
Eo, Kyung-Yeon (Department of Animal Health and Welfare, College of Healthcare and Biotechnology, Semyung University)
Publication Information
Korean Journal of Veterinary Service / v.45, no.2, 2022 , pp. 125-131 More about this Journal
Abstract
The purpose of this study was to examine antibody titers to structural protein (SP) of the foot-and-mouth disease (FMD) virus after vaccination in animals of the Seoul zoo. After the initial inoculation of FMD vaccine to the susceptible animals of the zoo, a total of 235 blood samples were collected from 42 species of zoo animals during treatment or necropsy. All samples were tested by using enzyme-linked immunosorbent assay (ELISA). The overall positive rate of SP antibodies against FMD virus was 94.0% (221/235). However, the positive rates varied according to animal species. The results of positive rates in 30 species were 100% but in 12 species were 50-94.7%. We showed that most animals that have received FMD vaccine in Seoul zoo have been reached to the level of herd immunity against FMD virus after the vaccination. To the best of our knowledge, this study would be the first report for monitoring the vaccine-induced SP antibody titers against FMD virus after vaccination in various zoo animal species in Korea.
Keywords
Foot-and-mouth disease; Structural protein; ELISA; Antibody titer;
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