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http://dx.doi.org/10.7853/kjvs.2019.42.4.305

Safety test for propolis in beagle dogs based on hematology and serum biochemistry analysis  

Kang, Ikjae (Animal Disease Research Center, Dong Bang Co., Ltd.)
Publication Information
Korean Journal of Veterinary Service / v.42, no.4, 2019 , pp. 305-311 More about this Journal
Abstract
The objective of this study was to determine the safety test for propolis in Beagle based on blood count, serum biochemistry, and electrolyte. Total six beagle dogs were assigned to this experiment. To investigate the safety of propolis in beagle dogs, we performed oral administration of propolis (5%) for 8 weeks. Among six beagles, three beagle dogs were randomly allocated to the control group which were fed only regular fodder, and the other three dogs were assigned as the treatment group which were fed regular fodder and propolis (5%). No clinical signs were observed in neither group throughout the experimental period. During the experimental period, there were no significant change in feed intake, water consumption, and body condition. Also, there were no statistically significant differences in hematological and biochemical analyses between the control group and the treated group. Our safety study showed that oral consumption of propolis did not cause any toxicological effects in beagle dogs.
Keywords
Propolis; Beagle; Hematology; Serum biochemistry; Safety;
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