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http://dx.doi.org/10.7853/kjvs.2016.39.3.199

Malignant melanoma in a grey pony, Korea  

Kim, Ji-Hyeon (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency)
Lee, Hyunkyoung (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency)
Lee, Kyunghyun (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency)
Baek, Kanghyun (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency)
Choi, Eunjin (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency)
So, ByungJae (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency)
Yang, Siyeon (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency)
Publication Information
Korean Journal of Veterinary Service / v.39, no.3, 2016 , pp. 199-204 More about this Journal
Abstract
A 16 year-old female grey pony was presented to Animal and Plant Quarantine agency for diagnosis in Feb 2, 2015. At necropsy, multiple pigmented masses, likely melanomas, were detected peri-anally and under the tail. Further metastatic spread to the spleen, liver, lung and lymph nodes was also identified. Histopathologically, anaplastic and pleomorphic melanocytes were observed in the mass. By immunohistochemistry, PNL2, S100 and PGP 9.5 protein were detected, but Melan A was not expressed in the neoplastic melanocytes. Based on the pathological and immunohistochemical examination, we diagnosed this case as malignant melanoma in a grey pony. To the authors' knowledge, this is the first report of equine malignant melanoma in republic of Korea.
Keywords
Grey horse; Malignant melanoma; Metastasis;
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