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Surveys on the residual level of fluoroquinolones in eggs  

Koh Ba-Ra-Da (Gwangju Metropolitan Health & Environment Research Institute)
Park Seong-Do (Gwangju Metropolitan Health & Environment Research Institute)
Jang Mi-Sun (Gwangju Metropolitan Health & Environment Research Institute)
Na Ho-Myung (Gwangju Metropolitan Health & Environment Research Institute)
Kim Yong-Hwan (Gwangju Metropolitan Health & Environment Research Institute)
Publication Information
Korean Journal of Veterinary Service / v.28, no.3, 2005 , pp. 235-243 More about this Journal
Abstract
This surveies were carried out to investigate the residual levels of fluoroquinolones in chicken and quail eggs by bioassay and HPLC method. The eggs of 240 samples collected from market and farm in Gwangju Metropolitan city were examined from May to December in 2003. Residual antibiotic materials were detected from 47 samples of the 240 eggs by bioassay. Of the 240 eggs assayed, ciprofloxacin, danofloxacin, norfloxacin, ofloxacin, orbifloxacin and perfloxacin were not detected but enrofloxacin was detected from 5 samples in 228 chicken eggs and 1 sample in 12 quail eggs using HPLC with fluorescence detector by multi-residue method. 2 sample eggs in 6 sample which were detected by HPLC were not positive with bioassay. The average residual concentration of enrofloxacin was 0.494 mg/kg in 6 positive samples. The highest residual concentration of enrofloxacin was 1.83mg/kg.
Keywords
Residual antibiotics; Bioassay; Fluoroquinolones; HPLC;
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  • Reference
1 농림부. 2002. 축산법
2 축산물등급판정소. 2002. 계란등급판정기준및방법
3 Burgat V. 1991. Residues of drugs veterinary use in food. Rev Pract 41 : 985-990
4 Kang HG, Son SW, Lee HS, et al. 1997. Matrix Solid Phase Dispersion (MSPD) extration and HPLC determination of enrofloxacin and ciprofloxacin in pork muscle tissue. Korean J Vet Res 37:195-202
5 Meetschen U, Petz M. 1990. Capillary gas chromatographic method for determination of benzylpenicillin and other beta-lactam antibiotics in milk. JAOAC Int 73:373-378
6 Rogers ME, Adlard MW. Saunders G, et al. 1984. Derivatization techniques for high performance liquid chromatographic analysis of beta-lactams. J chromatogr 297:385-391   DOI   ScienceOn
7 한석현. 1996. 계란의 과학과 그 이용. 선진문화사, 서울
8 Gigosos PG, Revesado PR, Cadahia O, et al. 2000. Determination of quinolones in animal tissues and eggs by high performance liquid chromatography with photodiode-array detection. J Chromato A 871:31-36   DOI   PUBMED   ScienceOn
9 농림부. 2002. 축산물가공처리법
10 Schneider MJ, Donoghue DJ. 2000. Multiresidue determination of fluoroquinolones in eggs. J AOAC Int 83:1306-1312
11 서계원, 이재일, 이채용 등. 2002. MSPD법과 HPLC를 이용한 계란내 플루오로퀴놀론계 항균물질의 동시 다성분 정량분석. 한국수의공중보건학회지 26:269- 281
12 서계원. 2000. 계란 중 Fluoroquinolone계 합성항균제의 잔류에 관한 연구. 전남대학교 박사학위논문:65-87
13 Zomer E, Quintana J, Saul S, et al 1995. A method for identification and quantitation of beta-lactams in milk by liquid chromatography with microbial receptor assay. JAOAC Int 78:1165-1172
14 이성기. 1999. 계란과 닭고기의 과학. 유한문화사, 서울
15 EEC, Council Regulation(EC) No 434/97 amending Regulation(EEC) No 2377/90. Off J Eur Commun, L 244/1, 1990
16 Moats WA. 1997. Advances in determination of antibiotic residues. J AOAC 80 : 1-4
17 서계원, 이재일, 이채용 등. 2002. 산란계에 투여된 플루오로퀴놀론계 합성항균제의 계란내 이행 잔류 연구. 한국수의공중보건학회지 26:249-259
18 Cutting JH, Kiessling WM, Bond FL, et al. 1995. Agarose gel electrophoretic detection of six beta-lactam antibiotic residues in milk. JAOAC Int 78:663-667
19 식품의약품안전청. 2002.식품의기준및규격
20 Chu PS, Wang RC, Chu HV. 2002. Liquid chromatographic determination of fluoroquinolones in egg albumen and egg yolk of laying hens using fluorometric detection. J Agric Food Chem 50:4452-4455   DOI   ScienceOn
21 Boison JO, Salisbury CDC, Waynechan, et al. 1991. Determination of penicillin G residues in edible animal tissues by liquid chromatography. JAOAC Int 74:497-501