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The effects of the Korea chinese chives ethyl acetate on hematological changes in dog  

Park Mi-Jung (Eastern Branch, Gyeongbuk Veterinary Service Laboratory)
Lee Sung-Dong (Eastern Branch, Gyeongbuk Veterinary Service Laboratory)
Kim Ha-Dong (Eastern Branch, Gyeongbuk Veterinary Service Laboratory)
Kim Joo-Wan (Eastern Branch, Gyeongbuk Veterinary Service Laboratory)
Song Jae-Chan (Eastern Branch, Gyeongbuk Veterinary Service Laboratory)
Kim Young-Hong (Eastern Branch, Gyeongbuk Veterinary Service Laboratory)
Oh Tae-Ho (Eastern Branch, Gyeongbuk Veterinary Service Laboratory)
Lee Keun-Woo (College of Veterinary Medicine, Kyungpook National University)
Publication Information
Korean Journal of Veterinary Service / v.27, no.3, 2004 , pp. 249-256 More about this Journal
Abstract
The Korea chinese chives are a major edible vegetable and they are traditionally been used as a folk medicine. However recently studies on the Allium tuberosum are mainly on the morphological property and the chemical constituent. There are no reports concerning hematological changes in dogs administrated ethyl acetate extracts of Korea chinese chive. This experiment was conducted to investigate the hematological changes in dogs administrated ethyl acetate extracts of the Korea chinese chives($5m{\ell}/mg$) for 6 days. During administration blood samples were collected at 3h, 6h, 12h and then on daily basis until day 6. Blood samples were analyzed red blood cell(RBC), packed cell volume(PCV), hemoglobin concentration(Hb), mean corpuscular volume(MCV), mean corpuscularl hemoglobin concentration(MCHC), reduced glutathion(GSH), and met-hemoglobin concentration. The RBC count was significantly(p<0.01, p<0.05) decreased during experimental periods. Packed cell volume, hemoglobin concentration were not showed significantly difference during experimental periods. The MCV was significantly(p<0.01, p<0.05) increased from 3 hours after administration to day 4. The MCHC was significantly(p<0.05)decreased on day 6. GSH concentration was not showed significant difference during experimental periods and the met-hemoglobin concentration was significantly(p<0.05) increased on day 3.
Keywords
Korea chinese chives; Ethyl acetate; Hematological change;
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