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Effect of (-)-epigallocatechin-3-gallate on lipogenesis in 3T3-L1 Cell  

Kang, Shin-Seok (Northern Branch, Chungbuk Livestock and Veterinary Research Institute)
Park, Jae-Myung (Northern Branch, Chungbuk Livestock and Veterinary Research Institute)
Choi, Hae-Yeon (Northern Branch, Chungbuk Livestock and Veterinary Research Institute)
Cho, Woo-Young (Northern Branch, Chungbuk Livestock and Veterinary Research Institute)
Lee, Jong-In (Northern Branch, Chungbuk Livestock and Veterinary Research Institute)
Publication Information
Korean Journal of Veterinary Service / v.26, no.4, 2003 , pp. 339-343 More about this Journal
Abstract
We studied the effect of epigallocatechin-3-gallate(EGCG) on the adipose conversion of 3T3-L1 cells by insulin. In the 10 days of culture with insulin, the fat cells exhibited the increased and larger intracytoplasmic lipid droplets. In contrast, the levels of triglyceride(TG), a marker of adipose conversion, were decreased. However, the levels of glucose were decreased in the adipose conversion. In addition, levels of cholesterol were decreased in the differentiated 3T3-L1 cells.
Keywords
EGCG; Lipogenesis; 3T3-L1; Triglyceride;
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