Crystal Structure Analysis of 6-Ethoxy-3-phenyl-5a,9a-dihydro-3H-chromen[4,3-c][1,2]oxazole-3a(4H)-carbonitrile |
Malathy, P.
(CAS in Crystallography and Biophysics, University of Madras)
Sharmila, P. (Department of Physics, Presidency College) Srinivasan, J. (Department of Organic Chemistry, University of Madras) Manickam, Bakthadoss (Department of Organic Chemistry, University of Madras) Aravindhan, S. (Department of Physics, Presidency College) |
1 | W. Kemnitzer, S. Jiang, Y. Wang, S. Kasibhatla, C. Crogan-Grundy, M. Bubenik, D. Labrecque, R. Denis, S. Lamothe, G. Attardo, H. Gourdeau, B. Tseng, J. Drewe, and S. X. Cai, "Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based HTS assay. Part 5: Modifications of the 2- and 3-positions", Bioorg. Med. Chem. Lett., Vol. 18, pp. 603-607, 2008. DOI |
2 | P. Valenti, P. Da Re, A. Rampa, P. Montanari, M. Carrara, and L. Cima, "Benzo-gamma-pyrone analogues of geiparvarin: synthesis and biological evaluation against B16 melanoma cells", Anti-cancer Drug Design, Vol. 8, pp. 349-360, 1993. |
3 | G. T. Brooks, A. P. Ottridge, and D. W. Mace, "The effect of some furochromene and benzochromene analogues of 2,2-dimethyl-7-methoxychromene (precocene I) and benzofuran precursors on Oncopeltus fasciatus (dallas) and Locusta migratoria migratorioides (R&F)", J. Pestic. Sci., Vol. 22, pp. 41-50, 1988. DOI |
4 | Q.-G. Tang, W.-Y. Wu, W. He, H.-S. Sun, and C. Guo, "Methyl 2-amino-4-(3-fluoro-phen-yl)-4Hbenzo[h]chromene-3-carboxyl-ate methanol solvate", Acta Crystallographica Section E: Structure Reports Online, Vol. E63, pp. o1437-o1438, 2007. |
5 | M. Gabor and F. Kallay, "The pharmacology of benzopyrone derivatives and related compounds", Akademiai Kiado, 1986. |
6 | S. X. Cai, "Small molecule vascular disrupting agents: potential new drugs for cancer treatment", Recent Pat. Anti-Canc., Vol. 2, pp. 79-101, 2007. DOI |
7 | S. X. Cai, J. Drewe, and S. Kasibhatla, "A chemical genetics approach for the discovery of apoptosis inducers: from phenotypic cell based HTS assay and structure-activity relationship studies, to identification of potential anticancer agents and molecular targets", Curr. Med. Chem., Vol. 13, pp. 2627-2644, 2006. DOI |
8 | S. X. Cai, J. Drewe, and W. Kemnitzer, "Discovery of 4-aryl-4H-chromenes as potent apoptosis inducers using a cell- and caspase-based anti-cancer screening apoptosis program (ASAP): SAR studies and the identification of novel vascular disrupting agents", Anti-Cancer Agent. Me., Vol. 9, pp. 437-456, 2009. DOI |
9 | M. Kidwai, S. Saxena, M. K. R. Khan, and S. S. Thukral, "Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents", Bioorg. Med. Chem. Lett., Vol. 15, pp. 4295-4298, 2005. DOI |
10 | J.-L. Wang, D. Liu, Z.-J. Zhang, S. Shan, X. Han, S. M. Srinivasula, C. M. Croce, E. S. Alnemri, and Z. Huang, "Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells", P. Natl. Acad. Sci. U.S.A., Vol. 97, pp. 7124-7129, 2000. DOI |
11 | C. Bruhlmann, F. Ooms, P.-A. Carrupt, B. Testa, M. Catto, F. Leonetti, C. Altomare, and A. Carotti, "Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase", J. Med. Chem., Vol. 44, pp. 3195-3198, 2001. DOI |
12 | S. R. Kesten, T. G. Heffner, S. J. Johnson, T. A. Pugsley, J. L. Wright, and L. D. Wise, "Design, synthesis, and evaluation of chromen-2-ones as potent and selective human dopamine D4 antagonists", J. Med. Chem., Vol. 42, pp. 3718-3725, 1999. DOI |
13 | Bruker, "APEX2 and SAINT-Plus", Bruker AXS Inc., Madison, 2004. |
14 | G. M. Sheldrick, "MSHELXS-97 and SHELXL-97, Program for crystal structure solution and refinement", University of Gottingen, Gottingen, Germany, 1997. |
15 | G. M. Sheldrick, "A short history of SHELX", Acta Crystallogr. A, Vol. A64, pp. 112-122, 2008. |
16 | L. J. Farrugia, "ORTEP-3 for Windows-A version of ORTEP-III with a graphical user interface (GUI)", J. Appl. Crystallogr., Vol. 30, pp. 565, 1997. |
17 | A. L. Spek, "Structure validation in chemical crystallography", Acta Crystallogr. D., Vol. 65, pp. 148-155, 2009. DOI |
18 | L. J. Farrugia, "WinGX Suite for small-molecule single-crystal crystallography", J. Appl. Crystallogr., Vol. 32, pp. 837-838, 1999. DOI |
19 | G. Jagadeesan, J. Srinivasan, and M. Bakthadoss "Crystal structure analysis of methyl-3-phenyl-3H-chromeno[ 4,3-c]isoxazole-3a(4H)carboxylate", J. Chosun Natural Sci., Vol. 8, pp. 184-191, 2015. DOI |
20 | P. Malathy, G. Jagadeesan, J. Srinivasan , and M. Bakthadoss, ''Crystal structure analysis of 3-(4-ethylphenyl)- 3Hchromeno[4,3-c]isoxazole-3a(4H)-carbonitrile'', J. Chosun Natural Sci., Vol. 8, pp. 250-257, 2015. DOI |
21 | D. Cremer and J. A. Pople, "General definition of ring puckering coordinates". J. Am. Chem. Soc., Vol. 97, pp. 1354-1358, 1975. DOI |