1 |
S. J. Cho and A. Tropsha, "Cross validated R2 guided region selection for comparative molecular field analysis: a simple method to achieve consistent results", J. Med. Chem., Vol. 38, pp. 1060-1066, 1995.
DOI
ScienceOn
|
2 |
S. Wold, M. Sjostrom, and L. Eriksson, "PLS regression: a basic tool of chemometrics", Chemometr. Intell. Lab., Vol. 58, pp. 109-130, 2001.
DOI
ScienceOn
|
3 |
D. K. Perry, M. J. Smyth, H. R. Stennicke, G. S. Salvessan, P. Duriez, G. G. Poirier, and Y. A. Hannun, "Zinc is a potent inhibitor of the apoptotic protease, caspase-3. A novel target for zinc in the inhibition of apoptosis", J. Biol. Chem, Vol. 272, pp. 18530-18533, 1997.
DOI
ScienceOn
|
4 |
G. Porter and R. U. Janicke, "Emerging roles of caspase 3 in apoptosis", Cell Death Differ., Vol. 6, pp. 99-104, 1999.
DOI
ScienceOn
|
5 |
C. W. Scott, C. Sobotka-Brinker, D. E. Wilkins, R. T. Jacobs, J. J. Folmer, W. J. Frazee, R. V. Bhat, S. V. Ghanekar, and D. Aharony, "Novel small molecule inhibitors of caspase-3 block cellular and biochemical features of apoptosis", J. Pharmacol. Exp. Ther, Vol 304, pp. 433-440, 2003.
DOI
|
6 |
D. V. Kravchenko, V. M. Kysil, S. E. Tkachenko, S. Maliarchouk, I. M. Okun, and A. V. Ivanchtchenko, "Pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors. Synthesis and SAR of 2-substituted 4-methyl-8-(morpholine-4-sulfonyl)-pyrrolo [3,4-c]quinoline-1,3-diones", Eur. J. Med. Chem, Vol. 40, pp. 1377-1383, 2005.
DOI
|
7 |
W. Chu, J. Zhang, C. Zeng, J. Rothfuss, Z. Tu, Y. Chu, D.E. Reichert, M. J. Welch, and R. H. Mach, "N-Benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: Synthesis, in vitro activity and molecular modeling studies", J. Med. Chem, Vol. 48, pp. 7637-7647, 2005.
DOI
ScienceOn
|
8 |
L. M. Havrana, D. C. Chonga, W. E. Childersa, P. J. Dollingsa, A. Dietricha, B. L. Harrisona, V. Mar athiasa, G. Tawaa, A. Aulabaughb, R. Cowlingb, B. Kapoorb, W. Xuc, L. Mosyakc, F. Moyc, W.-T. Humc, A. Woodd, and A. J. Robichauda, "3.4-Dihydropyrimido( 1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3", Bioorgan. Med. Chem., Vol. 17, pp. 7755-7768, 2009.
DOI
ScienceOn
|
9 |
M. Thirumurthy, K. Gugan, G. Changdev, and S. J. Cho, "QSAR analysis on PfPK7 inhibitors using HQSAR, CoMFA and CoMSIA", Med. Chem. Res., Vol. 21, pp. 681-693, 2012.
DOI
|
10 |
D. W. Nicolson, "Caspase structure, proteolytic substrates, and function during apoptotic cell death", Cell Death Differ., Vol. 6, pp. 1028-1042, 1999.
DOI
ScienceOn
|
11 |
J. Wang and M. J. Lenardo, "Roles of caspases in apoptosis, development and cytokine maturation revealed by homozygous gene deficiencies", J. Cell Sci., Vol. 113, pp. 753-757, 2000.
|
12 |
R. E. Endres, S. Namura, M. Shomizu-Sasamata. C. Waeber, L. Zhang, T. Gomez-Isla, B. T. Hyman, and M. A. Moskowitz, "Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of caspase family", J. Cerebr. Blood F. Met., Vol. 18, pp. 238-247, 1998.
DOI
|
13 |
K. M. Boatright and G. S. Salvesen, "Mechanisms of caspase activation", Curr. Opin. Cell Biol., Vol. 15, pp. 725-731, 2003.
DOI
ScienceOn
|
14 |
B. A. Callus and D. L. Vaux, "Caspase inhibitors: viral, cellular and chemical", Cell Death Differ., Vol. 14, pp. 73-78, 2007.
DOI
|
15 |
B. R. Hu, C. L. Liu, Y. Ouyang, K. Blomgren, and B. K. Siesjo, "Involvement of caspase-3 in cell death after hypoxischemia declines during brain maturation", J. Cerebr. Blood F. Met., Vol. 20, pp. 1294-1300, 2000.
DOI
|
16 |
R. S. Hotchkiss, K. C. Chang, P. E. Swanson, K. W. Tinsley, J. J. Hui, P. Klender, S. Xanthoudakis, S. Roy, C. Black, E. Grimm, R. Aspiotis, Y. Han, D. W. Nicholson, and I. E. Karl, "Caspase inhibitors improves survival in sepsis: a critical role of the lymphocyte", Nat. Immunol., Vol.1, pp. 496-501, 2000.
DOI
ScienceOn
|
17 |
H. Yaoita, K. Ogawa, K. Maehara, and Y. Maruyama, "Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor", Circulation, Vol. 97, pp. 276-281, 1998.
DOI
ScienceOn
|
18 |
J. Schoenberger, J. Bauer, J. Moosbauer, C. Eilles, and D. Grimm, "Innovative strategies in in-vivo apoptosis imaging", Curr. Med. Chem, Vol. 15, pp. 187-194, 2008.
DOI
|
19 |
M. D. Jacobson, M. Weil, and M. C. Raff, "Programmed cell death in animal development", Cell, Vol. 88, pp. 347-54, 1997.
DOI
ScienceOn
|
20 |
G. M. Cohen, "Caspases: the executioners of apoptosis", J. Biochem., Vol. 326, pp. 1-16, 1997.
DOI
|
21 |
C. B. Thonberry and Y. Lazebnik, "Caspases: enemied within", Science, Vol. 281, pp. 1312-1316, 1998.
DOI
ScienceOn
|
22 |
R. S. Hotchkiss, K. C. Chang, P. E. Swanson, K. W. Tinsley, J. J. Hui, P. Klender, S. Xanthoudakis, S. Roy, C. Black, E. Grimm, R. Aspiotis, Y. Han, D. W. Nicholson, and I. E. Karl, "Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte", Nat. Immunol. Vol.1, pp. 496-501, 2000.
DOI
ScienceOn
|
23 |
D. Lee, S. A. Long, J. H. Murray, J. L. Adams, M.E. Nuttall, D. P. Nadeau, K. Kikly, J. D. Winkler, C.-M. Sung, M. D. Ryan, M. A. Levy, P. M. Keller, and W. E. DeWolf, Jr, "Potent and selective non peptide inhibitors of caspase 3 and 7", J. Med. Chem, Vol. 44, pp. 2015-2026, 2001.
DOI
ScienceOn
|