Browse > Article

Metabolic Syndrome and Bone Mineral Density among Elderly Korean Women  

Lee, Hae-Young (Seoul National University Hospital, Seoul National University)
ChoiKwon, Smi (College of Nursing, Research Institute of Nursing Science, Seoul National University)
Publication Information
Journal of Korean Biological Nursing Science / v.13, no.2, 2011 , pp. 134-141 More about this Journal
Abstract
Purpose: Although the risk factors of metabolic syndrome have been extensively studied, the association between osteoporosis and metabolic syndrome has remained unclear in Korean elderly women. Yet to be determined are the effect of risk factors of metabolic syndrome on osteoporosis in these subjects. The purpose of this study was to investigate how the risk factors of metabolic syndrome affect the bone mineral density in Korean elderly women. Methods: One hundred twenty one elderly women from a community center in Seoul elderly welfare center participated in this study. A structured questionnare was used to assess their demographics and lifestyles. Participants' anthropometric information was also obtained by measuring heights, weights, and waist circumferences. The blood samples were also obtained to measure blood glucoses and blood lipids. Bone mineral density was measured with the use of ultra sono. Results: The prevalence of metabolic syndrome in our subjects was 58%. In multivariate regression analysis, fasting plasma glucose level (p=.036) and triglycerides (p=.006) were significant factors predicting bone mineral density after adjusting age and other factors of metabolic syndrome. In age-adjusted analysis, women with metabolic syndrome had significantly higher bone mineral density as compared to those without metabolic syndrome (p=.026). Conclusion: Bone mineral density among elderly Korean women is associated with the level of blood glucose and triglycerides.
Keywords
Metabolic Syndrome; Bone Mineral Density; Elderly Women;
Citations & Related Records
Times Cited By KSCI : 6  (Citation Analysis)
연도 인용수 순위
1 Shin, M. H., Kweon, S. S., Park, S. K. S., Heo, H., Kim, S. J., Nam, H. S., et al. (2005). Quantitative ultrasound of the calcaneus in a Korean population: reference data and relationship to bone mineral density determined by peripheral dual X-ray absorptiometry. Journal of Korean Medical Science, 20, 1011-1016.   DOI   ScienceOn
2 Sung, K. W. (2011). Relationship of Daily Activity and Biochemical Variables in the Elderly with Diabetes Mellitus. Journal of Korean Academy of Nursing, 41, 182-190.   DOI
3 The fourth Korea National Health and Nutrition Examination Survey (KNHANES IV) (2009). Korean Ministry of Health and Welfare. 1-327.
4 Hernandez, J. L., Olmos, J. M., Pariente, E., Martinez, J., Valero, C., Garcia-Velasco, P., et al. (2010). Metabolic syndrome and bone metabolism: the Camargo Cohort study. Menopause, 17, 955-961.   DOI   ScienceOn
5 Hwang, D. K., & Choi, H. J. (2010). The relationship between low bone mass and metabolic syndrome in Korean women. Osteoporosis International, 21, 425-431.
6 Jeon, S. K., Hong, H. R., Yi, K. W., Park, H. T., Shin, J. H., Lee, N. W., et al. (2010). Relationship between metabolic syndrome and bone mineral density in middle-aged women. Journal of the Korean Society of Menopause, 16, 142-147.
7 Kim, H. Y., Choe J. W., Kim, H. K., Bae, S. J., Kim, B. J., Lee, S. H., et al. (2010). Negative association between metabolic syndrome and bone mineral density in Koreans, especially in men. Calcified Tissue International, 86, 350-358.   DOI   ScienceOn
8 Kim, M., Kim, J., Bae, W., Kim, S., Lee, Y., Na, W., et al. (2011). Relationship between nutrients intakes, dietary quality, and serum concentrations of inflammatory markers in metabolic syndrome patients. Korean Journal of Community Nutrition, 16(1), 51-61.
9 Kim, S. H. (2009). The effects of exercise program of obesity, physical fitness and metabolic syndrome in elderly women. Journal of the Korean Gerontological Society, 29, 823-935.
10 Kinjo, M., Setoguchi, S., & Solomon, D. H. (2007). Bone mineral density in adults with the metabolic syndrome: analysis in a population-based U. S. sample. The Journal of Clinical Endocrinology & Metabolism, 92, 4161-4164.   DOI   ScienceOn
11 Kang, H. S., Kim, J. I., Bak, W. S., Song, R. Y., Ahn, Y. H., Lee, I. O., et al. (2007). Relationship of obesity and bone mineral density in women dwelling in the community. Journal of Muscle and Joint Health, 14, 181-187.
12 Kim, H. M., Park, J., Ryu, S. Y., & Kim, J. (2007). The effect of menopause on the metabolic syndrome among Korean women: The Korean National Health and Nutrition Examination Survey. Diabetes Care, 30, 701-706.   DOI   ScienceOn
13 Macovey, J., Chen, J. S., Hayward, C., Williams, F. M., Sambrook, P. N. (2009). Association between serum cholesterol and bone mineral density. Bone, 44, 208-213.   DOI   ScienceOn
14 Koh, J. M., Khang, Y. H., Jung, C. H., Bae, S., Kim, D. J., Chung, Y. E., et al. (2005). Higher circulating hsCRP levels are associated with lower bone mineral density in health pre- and postmenopausal women: evidence for a link between systemic inflammation and osteoporosis. Osteoporosis Internetional, 16, 1263-1271.   DOI   ScienceOn
15 Leidig-Bruckner, G., & Ziegler, R. (2001). Diabetes mellitus a risk for osteoporosis? Experimental and Clinical Endocrinology and Diabetes, 109(Suppl 2), S493-S514.   DOI
16 Lipscombe, L. L., Jamal, S. A., Booth, G. L., & Hawker, G. A. (2007). The risk of hip fractures in older individuals with diabetes. Diabetes Care, 30, 835-841.   DOI   ScienceOn
17 Mikhail, M. B., Flaster, E., & Aloia, F. (1999). Stiffness in discrimination of patients with vertebral fractures. Osteoporosis International, 9(24), 24-28.
18 Rhee, E. J., Kim, Y. C., Lee, W. Y., Jung, C. H., Sung, K. C. Ryu, S. H., et al. (2006). Composition of insulin resistance and serum high-sensitivity C-reactive protein levels according to the fasting blood glucose subgroups divided by the newly recommended criteria for the fasting hyperglycemia in 10059 healthy Koreans. Metabolism, 55(2), 183-187.   DOI   ScienceOn
19 Park, J. C., Kweon, H. J., Oh, Y. K., Do, H. J., Oh, S. W., Lym, Y. L., et al. (2010). Association of the metabolic syndrome and bone mineral density in postmenopausal women. Korean Journal of Family Medicine, 31(1), 9-15.   DOI
20 Reid, I. R. (2002). Relationships among body mass, its components, and bone. Bone, 31, 547-555.   DOI   ScienceOn
21 Schwartz, A. V., Sellmeyer, D. E., Strotmeyer, E. S., Tylavsky, F. A., Feingold, K. R., Resnick, H. E., et al. (2005). Diabetes and bone loss at the hip in older black and white adults. Journal of Bone and Mineral Research, 20, 596-604.
22 Dekker, J. M., Girman, C., Rhodes, T., Nijpels, G., Stehouwer, C. D., Bouter, L. M., et al. (2005). Metabolic syndrome and 10-year cardiovascular disease risk in the Hoorn Study. Circulation, 112, 666-673.   DOI   ScienceOn
23 Shin, J. H., Hwang, Y. N., Kim, W. W., Kim, H. Y., Song, S. W. (2007). The relationship between the level of serum lipids and bone metabolism among pre and postmenopausal women. Journal of Korean Society for the Study of Obesity, 16(4), 162-169.
24 Vega, G. L. (2001). Results of experts meetings: obesity and cardiovascular disease. Obesity, the metabolic syndrome, and cardiovascular disease. American Heart Journal, 142, 1108-1116.   DOI   ScienceOn
25 World health Organization Expert Consultation. (2004). Appropriate body-mass index for asian populations and its implications for policy and intervention strategies. Lancet, 363, 157-163.   DOI   ScienceOn
26 WHO Western Pacific Region, International Association for the Study of Obesity, International Obesity Task Force. The Asia-Pacific perspective: redefining obesity and its treatment. Sydney: Health Communications Austrailia; 2000.
27 Adami, S., Braga, V., & Gatti, D. (2001). Association between bone mineral density and serum lipid in men. The Journal of the American Medical Association, 286, 791-792.   DOI   ScienceOn
28 Choi, S. H., & Choi-Kwon, S. (2010). The metabolic syndrome and associated life-style factors among older adults. Journal of Korean Biological Nursing Science, 13(1), 53-60.
29 Craig, C. L., Marshall, A. L., Sjostrom, M., Bauman, A. E., Booth, M. L., Ainsworth, B. E., et al. (2003). International physical activity questionnaire: 12-country reliability and validity. Medicine and Science in Sports and Exercise, 35, 1381-1395.   DOI   ScienceOn
30 Cui, L. H., Shin, M. H., Chung, E. K., Lee, Y. H., Kweon, S. S., Park, K. S., et al. (2005). Association between bone mineral densities and serum lipid profiles of pre- and post-menopausal rural women in South Korea. Osteoporosis International, 16, 1975-1981.   DOI   ScienceOn