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Reliability and Validity of Patient Self-reported Daily Questionnaire on Oral Mucositis in Acute Leukemic Patients under Chemotherapy  

Choi, So-Eun (Department of Nursing, Nambu University)
Kim, Hee-Seung (College of Nursing, The Catholic University)
Publication Information
Journal of Korean Biological Nursing Science / v.12, no.3, 2010 , pp. 148-156 More about this Journal
Abstract
Purpose: Oral mucositis (OM) is a serious consequence of chemotherapy that cancer patients must undergo. The objectives of this study were to find out reliability and validity of patients self-reported daily questionnaires on OM, and the impact OM makes on daily functions. Method: To test the reliability of oral mucositis daily questionnaire (OMDQ), internal consistency of the instrument (Cronbach's ${\alpha}$ and correlation between items) and test-retest reliability were analyzed. Criterion validity and discriminative validity were evaluated using WHO, oral assessment guide, and Nicolatou assessment tool. Forty-eight acute leukemic patients under chemotherapy were enrolled in this study. Result: The Cronbach's ${\alpha}$ coefficient indicated sufficient internal consistency. Correlations of Mouth and throat soreness (MTS) and MTSActivity Limitations (MTS-AL) were statistically significant. MTS and MTS-AL scores on consecutive days were highly correlated (days13,14=.84-.96; test-retest reliability). OMDQ scale had high criterion validity and discriminative validity. Patients with more severe WHO OM grades had higher MTS mean scores. Conclusion: Oral mucositis in acute leukemic patients under going chemotherapy can be easily quantified by patient self-administered OMDQ with reliability and validity.
Keywords
Leukemia; Oral mucositis; Reliability; Validity;
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1 Wardley, A. M., Jayson, G. C., Swindell, R., Morgenstern, G. R., Chang, J., Bloor, R., et al. (2000). Prospective evaluation of oral mucositis in patients receiving myeloablative conditioning regimens and haemopoietic progenitor rescue. British Journal of Haematology, 110, 292-299.   DOI   ScienceOn
2 Elting, L. S., Keefe, D. M., Sonis, S. T., Garden, A. S., Spijkervet, F. K., Barasch, A. et al. (2008). Patient-reported measurements of oral mucositis in head and neck cancer patients treated with radiotherapy with or without chemotherapy: Demonstration of increased frequency, severity, resistance to palliation, and impact on quality of life. Cancer, 113, 2704-2713.   DOI   ScienceOn
3 Quinn, B., Potting, C. M., Stone, R., Blijlevens, N. M., Fliedner, M., Margulies, A., et al. (2008). Guidelines for the assessment of oral mucositis in adult chemotherapy, radiotherapy and haematopoietic stem cell transplant patients. European Journal of Cancer, 44, 61-72.   DOI   ScienceOn
4 Sonis, S. T., Eilers, J. P., Epstein, J. B., LeVeque, F. G., Liggett, W. H., Jr, Mulagha, M. T. et al. (1999). Validation of a new scoring system for the assessment of clinical trial research of oral mucositis induced by radiation or chemotherapy. Mucositis Study Group. Cancer, 85, 2103-2113.   DOI   ScienceOn
5 Sonis, S. T., Elting, L. S., Keefe, D., Peterson, D. E., Schubert, M., Hauer-Jensen, M., et al. (2004). Perspectives on cancer therapyinduced mucosal injury: Pathogenesis, measurement, epidemiology, and consequences for patients. Cancer, 100 (9Suppl), 1995S-2025S.   DOI   ScienceOn
6 Nicolatou, O., Sotiropoulou-Lontou, A., Skarlatos, J., Kyprianou, K., Kolitsi, G., & Dardoufas, K. (1998). A pilot study of the effect of granulocyte-macrophage colony-stimulating factor on oral mucositis in head and neck cancer patients during X-radiation therapy: A preliminary report. International Journal of Radiation Oncology, Biology, Physcis, 42, 551-556.   DOI   ScienceOn
7 Tomlinson, D., Judd, P., Hendershot, E., Maloney, A. M., & Sung, L. (2007). Measurement of oral mucositis in children: A review of the literature. Supportive Care in Cancer, 15, 1251-1258.   DOI   ScienceOn
8 Turhal, N. S., Erdal, S., & Karacay, S. (2000). Efficacy of treatment to relieve mucositis -induced discomfort. Supportive Care in Cancer, 8, 55-58.
9 Stiff, P. J., Emmanouilides, C., Bensinger, W. I., Gentile, T., Blazar, B., Shea, T. C., et al. (2006). Palifermin reduces patient-reported mouth and throat soreness and improves patient functioning in the hematopoietic stem-cell transplantation setting. Journal of Clinial Oncology, 24, 5186-5193.   DOI   ScienceOn
10 Stiff, P. J., Erder, H., Bensinger, W. I., Emmanouilides, C., Gentile, T., Isitt, J. et al. (2006). Reliability and validity of a patient selfadministered daily questionnaire to assess impact of oral mucositis (OM) on pain and daily functioning in patients undergoing autologous hematopoietic stem cell transplantation (HSCT). Bone Marrow Transplantation, 37, 393-401.   DOI   ScienceOn
11 Ohrn, K. E. O., Wahlin, Y. B., & Sjoden, P. O. (2001). Oral status during radiotherapy and chemotherapy: A descriptive study of patient experiences and the occurrence of oral complications. Support Care Cancer. 9, 247- 257.   DOI   ScienceOn
12 Epstein, J. B., Beaumont, J. L,. Gwede, C. K., Murphy, B., Garden, A. S., & Meredith, R. (2007). Longitudinal evaluation of the oral mucositis weekly questionnaire-head and neck cancer, a patient-reported outcomes questionnaire. Cancer, 109, 1914-1922.   DOI   ScienceOn
13 Potting, C. M. J., Blijlevens, N. A. M., Donnelly, J. P., Feuth, T., & Van Achterberg, T. (2006). A scoring system for the assessment of oral mucositis in daily nursing practice. European Journal of Cancer Care, 15, 228-234.   DOI   ScienceOn
14 Rogers, B. B. (2001). Mucositis in the oncology patient. Nursing Clinics of North America, 36, 745-760.
15 Scully, C., Sonis, S., & Diz, P. D. (2006). Oral mucositis. Oral Diseases, 12, 229-241.   DOI   ScienceOn
16 Heo, S. L., Jung, M. A., Kim, H. S., Kwon, I. K., Hong, J. H., & Park, E. Y. (2003). The effect of GM-CSF oral gargle vs traditional betadine or chlorhexidine oral gargle in chemotherapy-induced stomatitis. Journal of Korean Clinical Nursing Research, 8, 169-182.
17 Jaroneski, L. A. (2006). The importance of assessment rating scales for chemotherapy-induced oral mucositis. Oncology Nursing Forum, 33, 1085-1090.   DOI   ScienceOn
18 Kushner, J. A., Lawrence, H. P., Shoval, I., Kiss, T. L., Devins, G. M., Lee, L. et al. (2008). Development and validation of a Patient-Reported Oral Mucositis Symptom (PROMS) scale. Journal of Canadian Dental Association, 74, 59.
19 Jung, Y. Y. (1996). Reliability testing of an oral assessment guide for patients receiving stomatoxic treatment. The Seoul Journal of Nursing, 10, 45-51.
20 Kim, Y. H., Jeon, M. H., & Choi, J. S. (1997). Prevention of chemotherapy induced oral mucositis in patients with acute leukemia by the two oral care protocols: The comparision of sodium bicarbonate normal saline gargling and chlorhexidine gargling. Journal of Korean Academy of Adult Nursing, 9, 98-111.
21 McGuire, D. B., Altomonte, V., Peterson, D. E., Wingard, J. R., Jones, R. J., & Grochow, L. B. (1993). Patterns of mucositis and pain in patients receiving preparative chemotherapy and bone marrow transplantation. Oncology Nursing Forum, 20, 1493-1502.
22 Byun, Y. S., & Kim, A. K. (1996). Experimental study for construction of mouth care in chemotherapy patients. Journal of Korean Academy of Nursing, 26, 428-442.
23 Dreizen, S. (1990). Description and incidence of oral complications. National Cancer Institute Monography, 9, 11-15.
24 A handbook for reporting results of cancer treatment. (1979). Geneva, Switzerland, World Health Organization.
25 Duncan, G. G., Epstein, J. B., Tu, D., El Sayed, S., Bezjak, A., Ottaway, J. et al. (2005). Quality of life, mucositis and xerostomia from radiotherapy for head and neck cancers. A report from the NCIC CTG HN2 randomized trial of an antimicrobial lozenge to prevent mucositis. Head Neck, 27, 421-428.   DOI   ScienceOn
26 Eilers, J., Berger, A. M., & Petersen, M. C. (1988). Development, testing, and application of the oral assessment guide. Oncology Nursing Forum, 15, 325-330.
27 Eilers, J., & Epstein, J. B. (2004). Assessment and measurement of oral mucositis. Seminars in Oncology Nursing, 20, 22-29.   DOI   ScienceOn
28 Brown, C. G., & Wingard, J. (2004). Clinical consequences of oral mucositis. Seminars in oncology Nursing, 20, 16-21.   DOI   ScienceOn
29 Beck, S. (1979). Impact of a systematic oral care protocol on stomatitis after chemotherapy. Cancer Nursing, 2, 185-199.
30 Bellm, L. A., Cunningham, G., Durnell, L., Eilers, J., Epstein, J. B., Fleming, T., et al. (2002). Defining clinically meaningful outcomes in the evaluation of new treatments for oral mucositis: Oral mucositis patient provider advisory board. Cancer Investigation, 20, 793-800.   DOI   ScienceOn