Browse > Article

Preparation and Swelling Behavior of Stimuli-responsive PHEMA Hybrid Gels  

Ahn, Jung-Hyun (School of Chemical Engineering, Polymer Technology Institute, Sungkyunkwan University)
Jeon, Young-Sil (School of Chemical Engineering, Polymer Technology Institute, Sungkyunkwan University)
Chung, Dong-June (Department of Polymer Science and Engineering, Sungkyunkwan University)
Kim, Ji-Heung (School of Chemical Engineering, Polymer Technology Institute, Sungkyunkwan University)
Publication Information
Polymer(Korea) / v.35, no.1, 2011 , pp. 94-98 More about this Journal
Abstract
Poly(2-hydroxyethyl methacrylate), PHEMA, hybrid gels containing Pluronic and acrylic acid (AAc) were prepared as new biocompatible and stimuli-responsive hydrogels by photo-polymerization technique. The prepared hybrid gel showed reversible, temperature-responsive swelling behavior due to the presence of Pluronic component, which underwent sol-gel transition at an elevated temperature to cause gel shrinkage. The hydrogel also exhibited increased swelling degrees and pH-sensitivity due to the AAc component with ionizable carboxylic acid groups. The microporous gel morphology and its changes upon stimuli was observed by scanning electron microscopy.
Keywords
PHEMA hydrogel; stimuli-responsive; swelling behavior; Pluronic;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
Times Cited By Web Of Science : 1  (Related Records In Web of Science)
Times Cited By SCOPUS : 1
연도 인용수 순위
1 Y. P. Jung, J. H. Kim, D. S. Lee, and Y. H. Kim, J. Appl. Polym. Sci., 104, 2484 (2007).   DOI   ScienceOn
2 K. H. Hong, Y. S. Jeon, and J. H. Kim, Macromol. Res., 17, 26 (2009).   DOI
3 A. S. Sosnik, D. Cohn, J. S. Roman, and G. A. Abraham, J. Biomater. Sci. Polym. Edn, 14, 227 (2003).   DOI   ScienceOn
4 S. H. Yuk, S. H. Cho, and Y. H. Bae, Polym. Sci. Tech., 12, 29 (2001).
5 L. E. Bromberg and J. E. Guillet, J. Macromol. Sci. Chem., A2, 1441 (1968).
6 W. F. Lee and C. H. Shieh, J. Appl. Polym. Sci., 73, 1955 (1999).   DOI   ScienceOn
7 F. Lim and A. M. Sun, Science, 201, 908 (1980).
8 O. Wichterle and D. Lim, Nature, 185, 117 (1960).   DOI
9 S. J. Kim, S. I. Shin, I. Y. Kim, and S. I. Kim, J. Appl. Polym. Sci., 96, 86 (2005).   DOI   ScienceOn
10 J. S. Calna, J. J. Pflug, A. S. Chhabra, and N. Raghupati, Br. J. Plast. Surg., 24, 113 (1971).   DOI
11 J. L. Drury and D. J. Mooney, Biomaterials, 24, 4337 (2003).   DOI   ScienceOn
12 J. L. Drury and D. J. Mooney, Biomaterials, 24, 4337 (2003).   DOI   ScienceOn
13 B. S. Kim, News & Information for Chemical Engineers, 24, 612 (2006).
14 H. He, X. Cao, and L. J. Lee, J. Control. Release, 95. 391 (2004).   DOI   ScienceOn
15 D. A. Chiappetta and A. Sosnik, Eur. J. Pharm. Biopharm., 66, 303 (2007).   DOI   ScienceOn