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Effect of In Vitro Degradation on the Weight Loss and Tensile Strength of PLA/PEG Melt Blend Fiber  

Yoon, Cheol-Soo (Department of Fiber System Engineering, Dankook University)
Ji, Dong-Sun (Department of Fiber System Engineering, Dankook University)
Publication Information
Polymer(Korea) / v.33, no.6, 2009 , pp. 581-587 More about this Journal
Abstract
PLA/PEG blend fibers composed of poly (lactic acid) (PLA) and poly (ethylene glycol) (PEG) were prepared via melt blending and spinning for bioabsorbable filament sutures. The blend fibers hydrolyzed with the immersion in a phosphate buffer solution at pH 7.4 and $37\;^{\circ}C$ for 1~8 weeks. The effects of blending time, blend composition, and hydrolysis time on the weight loss and tensile strength of the hydrolyzed blend fibers were investigated. After hydrolysis, the weight loss of the blend fibers increased with increasing PEG content, blending time, and hydrolysis time. The tensile strength and tensile modulus of the blend fibers decreased with increasing PEG content, blending time, and hydrolysis time. Therefore, it can be concluded that the weight loss of the PLA/PEG blend fibers was less than 0.9% even at hydrolysis time of 2 weeks and their strength retentions were over 90%.
Keywords
poly (lactic acid); poly (ethylene glycol); suture; tensile strength; hydrolysis;
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