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Preparation and Characterization of Electrospun Nanofibers Containing Natural Antimicrobials  

Kim, Young-Jin (Department of Biomedical Engineering, Catholic University of Daegu)
Kim, Sang-Nam (Department of Biomedical Engineering, Catholic University of Daegu)
Kwon, Oh-Kyoung (Department of Surgery, Gumi CHA General Hospital)
Park, Mi-Ran (Department of Polymer Science and Engineering, Kumoh National Institute of Technology)
Kang, Inn-Kyu (Department of Polymer Science, Kyungpook National University)
Lee, Se-Geun (Division of Nano & Bio Technology, Daegu Gyeongbuk Insititute of Science & Technology)
Publication Information
Polymer(Korea) / v.33, no.4, 2009 , pp. 307-312 More about this Journal
Abstract
The fabrication of PHBV nanofibers containing various plant polyphenols by electrospinning has been examined. It has been found that the average diameters of fibers increased by the adding of polyphenols. The resulting fibers exhibited a uniform diameter ranging from 340 to 450 nm. As the concentration of polyphenols increased, the diameter of fibers increased due to the hydrogen bonding interaction between the ester groups of PHBV and hydroxyl groups of polyphenols. The interaction between PHBV and polyphenols, which forms a complex together in solution, was verifed by UV measurement. ATR-FTIR analysis confirmed the existence of the hydrogen bonding interaction. The semicrystalline structure of the PHBV nanofiber was observed from XRD pattern. The crystallinity of PHBV nanofibers was increased by the adding of polyphenols. PHBV nanofibers containing polyphenols showed superior antimicrobial activities.
Keywords
electrospinning; PHBV; nanofiber; plant polyphenol; natural antimicrobial;
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1 J. F. Hammerstone, S. A. Lazarus, and H. H. Schmitz, J. Nutr., 130, 2086 (2000)
2 J. Jankun, S. H. Selman, R. Swiercz, and E. Skrzypezak- Jankun, Nature, 387, 561 (1997)   DOI   ScienceOn
3 S. Hemaiswarya, A. K. Kruthiventi, and M. Doble, Phytomedicine, 15, 639 (2008)   DOI   ScienceOn
4 H. Guan, C. Shao, S. Wen, B. Chen, J. Gong, and X. Yang, Mater. Chem. Phys., 82, 1002 (2003)   DOI   ScienceOn
5 Z. M. Huang, Y. Z. Zhang, M. Kotaki, and S. Ramakrishna, Compos. Sci. Technol., 63, 2223 (2003)   DOI   ScienceOn
6 B. M. Min, G. Lee, S. H. Kim, Y. S. Nam, T. S. Lee, and W. H. Park, Biomaterials, 25, 1289 (2004)   DOI   ScienceOn
7 R. A. Caruso, J. H. Schattka, and A. Greiner, Adv. Mater., 13, 1577 (2001)   DOI   ScienceOn
8 R. Langer and J. P. Vacanti, Science, 260, 920 (1993)   DOI   PUBMED
9 G. T. Kose, H. Kenar, H. Hasırcı, and V. Hasırcı, Biomaterials, 24, 1949 (2003)   DOI   ScienceOn
10 N. Yoshie, M. Saito, and Y. Inoue, Macromolecules, 34, 8953 (2001)   DOI   ScienceOn
11 Y. K. Ko, S. H. Kim, J. S. Jeong, H. J. Ha, S. J. Yoon, J. M. Rhee, M. S. Kim, H. B. Lee, and G. Khang, Polymer (Korea), 31, 14 (2007)
12 C. W. Pouton and S. Akhtar, Adv. Drug Del. Rev., 18, 133 (1996)   DOI   ScienceOn
13 H. Yoshimoto, Y. M. Shin, H. Terai, and J. P. Vacanti, Biomaterials, 24, 2077 (2003)   DOI   ScienceOn
14 W. Ye, M. F. Leung, J. Xin, T. L. Kwong, D. K. L. Lee, and P. Li, Polymer, 46, 10538 (2005)   DOI   ScienceOn
15 A. Padermshoke, Y. Kastumoto, H. Sato, S. Ekgasit, I. Noda, and Y. Ozaki, Polymer, 45, 6547 (2004)   DOI
16 W. J. Li, T. Laurencin, E. J. Caterson, R. S. Tuan, and F. K. Ko, J. Biomed. Mater. Res., 60, 613 (2002)   DOI   ScienceOn
17 M. Lopez, F. Martínez, C. Del Valle, C. Orte, and M. Miro, J. Chromatogr., 922, 359 (2001)   DOI   ScienceOn
18 F. Shahidi and M. Naczk, Phenolic in Food and Nutraceuticals: Sources, Applications, and Health Effects, CRC Press, Boca Raton, FL, 2003
19 W. Ren, Z. Qiao, H. Wang, and L. Zhang, Med. Res. Rev., 23, 519 (2003)   DOI   ScienceOn
20 Y. J. Kim, H. Uyama, and S. Kobayashi, Macromolecules, 36, 5058 (2003)   DOI   ScienceOn
21 Y. J. Kim, H. Uyama, and S. Kobayashi, Macromol. Biosci., 4, 497 (2004)   DOI   ScienceOn
22 G. Di Carlo, N. Mascolo, A. A. Izzo, and F. Capasso, Life Sci., 65, 337 (1999)   DOI   ScienceOn
23 W. Huang, M. Z. Liu, Y. Li, Y. Tan, and G. F. Yang, Bioorgan. Med. Chem., 15, 5191 (2007)
24 J. Zeng, X. Xu, X. Chen, Q. Liang, X. Bian, L. Yang, and X. Jing, J. Control. Release, 92, 227 (2003)   DOI   ScienceOn
25 L. Huang, R. A. McMillan, R. P. Apkarian, B. Pourdeyhimi, V. P. Contocello, and E. L. Chaikof, Macromolecules, 33, 2989 (2000)   DOI   ScienceOn
26 M. M. Cowan, Clin. Microbiol. Rev., 12, 564 (1999)   PUBMED   ScienceOn
27 Z. Chen, M. D. Forster, W. Zhou, H. Fong, and D. H. Reneker, Macromolecules, 34, 6156 (2001)   DOI   ScienceOn
28 S. H. Cho, S. H. Oh, and J. H. Lee, J. Biomater. Sci. Polym. Ed., 16, 933 (2005)   DOI   ScienceOn
29 G. Ginaalska, D. Kowalczuk, and M. Osinska, Intern. J. Pharm., 288, 131 (2008)   DOI   ScienceOn
30 A. B. Samuelsen, J. Ethnopharmacol., 71, 1 (2000)   DOI   PUBMED   ScienceOn
31 H. Tsuchiya, M. Sato, T. Miyazaki, S. Fujiwara, S. Tanigaki, M. Ohyama, T. Tanaka, and M. Iinuma, J. Ethnopharmacol., 50, 27 (1996)   DOI   ScienceOn