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Degradation Behavior of Medical Resorbable Composite Materials Interposed in the Poly(glycolic acid)  

Lee, Chan-Woo (Department of Innovative Industrial Technology, Hoseo University)
Publication Information
Polymer(Korea) / v.31, no.3, 2007 , pp. 233-238 More about this Journal
Abstract
The purpose of the study is to apply composites of poly (glycolic acid) (PGA) with [poly(R) 3-hydroxybutyrate] (P3HB) or poly (butylenes succinate- co-L-lactate) (PBSL) as medical resorbable composite materials with the complement of hydrolysis rate of each component. As a result, it was confirmed that the PBSL/PGA and P3HB/PGA composite fiber were hydrolyzed in phosphate buffer solution. Also, it has been revealed that the degradation of PBSL/PGA are accelerated due to PGA producing glycolic acid which can act as a catalyst. In addition, the hydrolysis of PBSL/PGA was found to be accelerated by the presence of lipase PS. When the PBSL/PGA composite fiber was placed in the air, not much hydrolysis has proceeded. Also, it was confirmed that the P3HB/PGA composite fiber maintained proper tensile strength in the air. Therefore, these complex fibers can be adapted to use as environmentally suitable, medically absorbable composite materials.
Keywords
phosphate buffer; decomposition; hydrolysis; degradation; composite fibrous; medical resorbable composite materials;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
Times Cited By Web Of Science : 2  (Related Records In Web of Science)
Times Cited By SCOPUS : 2
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