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http://dx.doi.org/10.7739/jkafn.2018.25.3.176

Chemotherapy Induced Peripheral Neuropathy, Sleep and Quality of Life among Patients with Gastric Cancer Receiving Chemotherapy  

Kim, Hyemi (National Cancer Center.Graduate School of Clinical Health Sciences, Ewha Womans University)
Park, Hyojung (College of Nursing.Ewha Research Institute of Nursing Science, Ewha Womans University)
Publication Information
Journal of Korean Academy of Fundamentals of Nursing / v.25, no.3, 2018 , pp. 176-184 More about this Journal
Abstract
Purpose: Purpose of this study was to investigate relationships and influence of peripheral neuropathy, sleep, and quality of life in patients with gastric cancer who are receiving chemotherapy. Methods: Participants were 131 patients with gastric cancer being treated at a chemotherapy outpatient clinic and receiving chemotherapy. Data were analyzed using descriptive statistics, t-test, ANOVA, and multiple regression analysis with the SPSS program. Results: Mean score for peripheral neuropathy was 24.66, for sleep, 6.71 and for quality of life, 67.69. Peripheral neuropathy had a significant positive correlation with sleep (r=.26, p=.003) and sleep had a significant negative correlation with quality of life (r=-.50, p<.001). The regression model explaining quality of patients'lives was significant (F=11.91, p<.001), peripheral neuropathy, sleep, and pain due to anticancer drugs and number ofneurotoxic anticancer drugs explained 25.1% of the variance in quality of life and sleep was the most important factor. Conclusion: To improve the quality of life for these patients, individualized nursing interventions for pain should be provided according to number of anticancer drugs in the chemotherapy. Also there is a need to identify ways to assess peripheral neuropathy and sleep disorders that are appropriate in the treatment and reduce side effects during treatment.
Keywords
Chemotherapy adjuvant; Stomach neoplasms; Peripheral neuropathy; Sleep; Quality of life;
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