[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.5757/ASCT.2015.24.5.190

A Reusable Pb²⁺ Detecting Aptasensor Employing a Gold Nanorod-DNAzyme Conjugate

Lee, Jayeon (Nanobiotechnology (Major), KRIBB Campus, Korea University of Science and Technology)
Ha, Tai Hwan (Nanobiotechnology (Major), KRIBB Campus, Korea University of Science and Technology)

Publication Information

Applied Science and Convergence Technology / v.24, no.5, 2015 , pp. 190-195 More about this Journal

Abstract

Here, we demonstrated a $Pb^{2+}$ detecting aptasensor using $Pb^{2+}$ -sensitive DNAzyme-conjugated gold nanorods (GNRs). Fluorescent DNA substrates that were initially quenched by GNRs, are released in response to $Pb^{2+}$ ions to give a substantial fluorescence signal. The GNR-tethered DNAzyme is reusable at least three times with a LOD of 50 nM.

Keywords

DNAzyme; Heavy metal ions; Gold nanorod; Aptamer;

Citations & Related Records

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KSCI

A Reusable Pb2+ Detecting Aptasensor Employing a Gold Nanorod-DNAzyme Conjugate

A Reusable Pb²⁺ Detecting Aptasensor Employing a Gold Nanorod-DNAzyme Conjugate