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http://dx.doi.org/10.4313/TEEM.2015.16.2.65

Low-level Green and Red Laser Treatment of Shaochong (HT9)·Dadun (LR1) and Shaohai (HT3)·Yingu (KI10) Acupoints in a Rat Model of Focal Cerebral Ischemia  

Na, Chang-Su (Department of Acupoint & Meridian, Oriental Medical School, Dongshin University)
Kim, Wang-In (Department of Acupoint & Meridian, Oriental Medical School, Dongshin University)
Jang, Ho-Sun (Department of Acupoint & Meridian, Oriental Medical School, Dongshin University)
Youn, Dae-Hwan (Department of Acupoint & Meridian, Oriental Medical School, Dongshin University)
Moon, Young-Min (Department of Medical System Engineering, Gwangju Institute of Science and Technology)
Jeong, Sung-Ho (School of Mechatronics, Gwangju Institute of Science and Technology)
Cheon, Min-Woo (Department of Health Administration, Dongshin University)
Publication Information
Transactions on Electrical and Electronic Materials / v.16, no.2, 2015 , pp. 65-69 More about this Journal
Abstract
Low level laser therapy (LLLT) has facilitated an improvement in acupuncture treatment. In this study, we stimulated Shaochong (HT9), Dadun (LR1), Shaohai (HT3), and Yingu (KI10) acupoints with pulsed laser diodes 532 nm [green laser] and 658 nm [red laser] in rats with induced middle cerebral artery occlusion(MCAO). The animals were divided into 6 groups: intact control; MCAO control without LLLT; LLLT with red laser at HT9·LR1 and HT3·KI10 (RR); LLLT with green laser at HT9·LR1 and HT3·KI10 (GG); LLLT with green laser at HT9·LR1 and red laser at HT3·KI10 (GR); and LLLT with red laser at HT9·LR1 and green laser at HT3·KI10 (RG). We evaluated the immunohistochemical changes in the hippocampal CA1 region, and complete blood count changes. Compared to the MCAO control group, the RG group showed a significant decrease in Bax and cytochrome c levels in the hippocampus, and a significant increase in hemoglobin level, hematocrit, total white blood cell, neutrophil, lymphocyte, monocyte, and erythrocyte counts.
Keywords
LLLT; MCAO; Acupoint; Focal brain ischemia; Reinforcement-reduction;
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