Browse > Article
http://dx.doi.org/10.5573/JSTS.2016.16.4.436

A 95% accurate EEG-connectome Processor for a Mental Health Monitoring System  

Kim, Hyunki (School of EE, KAIST)
Song, Kiseok (K-Healthware)
Roh, Taehwan (K-Healthware)
Yoo, Hoi-Jun (School of EE, KAIST)
Publication Information
JSTS:Journal of Semiconductor Technology and Science / v.16, no.4, 2016 , pp. 436-442 More about this Journal
Abstract
An electroencephalogram (EEG)-connectome processor to monitor and diagnose mental health is proposed. From 19-channel EEG signals, the proposed processor determines whether the mental state is healthy or unhealthy by extracting significant features from EEG signals and classifying them. Connectome approach is adopted for the best diagnosis accuracy, and synchronization likelihood (SL) is chosen as the connectome feature. Before computing SL, reconstruction optimizer (ReOpt) block compensates some parameters, resulting in improved accuracy. During SL calculation, a sparse matrix inscription (SMI) scheme is proposed to reduce the memory size to 1/24. From the calculated SL information, a small world feature extractor (SWFE) reduces the memory size to 1/29. Finally, using SLs or small word features, radial basis function (RBF) kernel-based support vector machine (SVM) diagnoses user's mental health condition. For RBF kernels, look-up-tables (LUTs) are used to replace the floating-point operations, decreasing the required operation by 54%. Consequently, The EEG-connectome processor improves the diagnosis accuracy from 89% to 95% in Alzheimer's disease case. The proposed processor occupies $3.8mm^2$ and consumes 1.71 mW with $0.18{\mu}m$ CMOS technology.
Keywords
Connectome; EEG processor; brain disease; synchronization likelihood; wearable;
Citations & Related Records
연도 인용수 순위
  • Reference
1 H. Kim, K. Song, T. Roh, and H. -J. Yoo, "A 95% accurate EEG-connectome processor for a mental health monitoring system," Asian Solid-State Circuits Conference (A-SSCC), Nov. 2015.
2 T. Roh, S. Hong, H. Cho, and H. -J. Yoo, "A $259.6-{\mu}m$ nonlinear HRV-EEG chaos processor with body channel communication interface for mental health monitoring," ISSCC Dig. Tech. Papers, Feb. 2012, pp. 294-296.
3 T. Roh, K. Song, H. Cho, D. Shin, U. Ha, K. Lee, and H. -J. Yoo, "A 2.14mW EEG neuro-feedback processor with transcranial electrical stimulation for mental-health management," ISSCC Dig. Tech. Papers, Feb. 2014, pp. 318-319.
4 M. Ahmadlou, H. Adeli, and A. Adeli, "Graph theoretical analysis of organization of functional brain networks in ADHD," Clinical EEG and Neuroscience, vol. 43, no. 1, pp. 5-13, 2012.   DOI
5 C. J. Stam, B. F. Jones, G. Nolte, M. Breakspear, and Ph. Scheltens, "Small-world networks and functional connectivity in Alzheimer's disease," Cerebral Cortex, vol. 17, no. 1, pp. 92-99, 2007.   DOI
6 E. T. Bullmore, and D. S. Bassett, "Brain graphs: graphical models of the human brain connectome," Annual review of clinical psychology, vol. 7, pp. 113-140, 2011.   DOI
7 C. J. Stam, "Nonlinear dynamical analysis of EEG and MEG: review of an emergning field," Clinical Neurophysiology, vol. 116, no. 10, pp. 2266-2301, 2005.   DOI
8 M. Kennel, R. Brown, and H. D. Abarbanel, "Determining embedding dimension for phase-space reconstruction using a geometrical construction," Physical review A, vol. 45, no. 6, p. 3404, 1992.
9 W. Chen, et al., "A fully integrated 8-channel closed-loop neural prosthetic SoC for real-time epileptic seizure control," ISSCC Dig. Tech. Papers, Feb. 2013, pp. 286-287.
10 M. A. B. Altif, C. Zhang, and J. Yoo, "A 16-ch patient-specific seizure onset and termination detection SoC with machine-learning and voltagemode transcranial stimulation," ISSCC Dig. Tech. Papers, Feb. 2015, pp. 394-395.