[KSCI] Korea Science Citation Index Service

Effects of Ethanol Extract of Potato (Solanum tuberlosum) on Freund's Complete Adjuvant-induced Model of Chronic Arthritis in Mice

Choi, Eun-Mi (Department of Food & Nutrition, Kyung-Hee University)
Lee, Kyung-Hee (Department of Food Service Management, Kyung-Hee University)
Koo, Sung-Ja (Department of Food & Nutrition, Kyung-Hee University)

Publication Information

Food Science and Biotechnology / v.14, no.2, 2005 , pp. 228-232 More about this Journal

Abstract

The effect of a potato ethanol extract was investigated on Freund's complete adjuvant (FCA)-induced arthritis. The oral administration of the potato extract, at doses of 100 and 200 mg/kg once a day for 21 days, significantly reduced hindpaw swelling and the production of inflammatory cytokines (TNF- ${\alpha}$ , IL- $1{\beta}$ and IL-6). Treatment with the potato extract also decreased the plasma levels of creatinine, triglyceride and LDL-cholesterol, and the activities of AST and ALT compared with those of a control group. These results suggest that the potato extract might be beneficial in the treatment of chronic inflammatory disorders.

Keywords

Solanum tuberosum; inflammation; Freund's complete adjuvant; arthritis;

Citations & Related Records

Times Cited By Web Of Science : 2 (Related Records In Web of Science)

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