Browse > Article
http://dx.doi.org/10.1016/j.shaw.2019.03.003

Occupational Characteristics of Semiconductor Workers with Cancer and Rare Diseases Registered with a Workers' Compensation Program in Korea  

Park, Dong-Uk (Department of Environmental Health, Korea National Open University)
Choi, Sangjun (Department of Occupational Health, Catholic University of Daegu)
Lee, Seunghee (Department of Environmental Health, Korea National Open University)
Koh, Dong-Hee (Department of Occupational and Environmental Medicine, International St. Mary's Hospital, Catholic Kwandong University)
Kim, Hyoung-Ryoul (Department of Occupational and Environmental Medicine, College of Medicine, Catholic University)
Lee, Kyong-Hui (United States Army 65th Medical Brigade, Force Health Protection and Preventive Medicine Unit 15281)
Park, Jihoon (Institute of Health and Environment, Graduate School of Public Health, Seoul National University)
Publication Information
Safety and Health at Work / v.10, no.3, 2019 , pp. 347-354 More about this Journal
Abstract
Background: The aim of this study was to describe the types of diseases that developed in semiconductor workers who have registered with the Korea Workers' Compensation and Welfare Service (KWCWS) and to identify potential common occupational characteristics by the type of claimed disease. Methods: A total of 55 semiconductor workers with cancer or rare diseases who claimed to the KWCWS were compared based on their work characteristics and types of claimed diseases. Leukemia, non-Hodgkin lymphoma, and aplastic anemia were grouped into lymphohematopoietic (LHP) disorder. Results: Leukemia (n = 14) and breast cancer (n = 10) were the most common complaints, followed by brain cancer (n = 6), aplastic anemia (n = 6), and non-Hodgkin lymphoma (n = 4). LHP disorders (n = 24) accounted for 43%. Sixty percent (n = 33) of registered workers (n = 55) were found to have been employed before 2000. Seventy-six percent (n = 42) of registered workers and 79% (n = 19) among the registered workers with LHP (n = 24) were found to be diagnosed at a relatively young age, ${\leq}40years$. A total of 18 workers among the registered semiconductor workers were finally determined to deserve compensation for occupational disease by either the KWCWS (n = 10) or the administrative court (n = 8). Eleven fabrication workers who were compensated responded as having handled wafers smaller than eight inches in size. Eight among the 18 workers compensated (44 %) were found to have ever worked at etching operations. Conclusion: The distribution of cancer and rare diseases among registered semiconductor workers was closely related to the manufacturing era before 2005, ${\leq}8$ inches of wafer size handled, exposure to clean rooms of fabrication and chip assembly operations, and etching operations.
Keywords
Chip assembly; Etching; Fabrication; Leukemia; Semiconductor operation;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Singapore Ministry of Manpower. A Guide on health hazards and their control in wafer fabrication facilities. Occupational Safety and Health Division; 1998.
2 Baldwin D, King B, Scarpace L. Ion Implanters-Chemical and radiation safety. Solid State Technol 1988;31:99-105.   DOI
3 Van Zant P, Chapman P. Microchip fabrication: a practical guide to semiconductor processing. New York: McGraw-Hill; 2000.
4 Hawkinson TE. Chemical hazards in semiconductor operations. Semiconductor safety handbook: safety and health in the semiconductor industry. New York: William Andrew Publishing/Noyes; 1998. p. 163-79.
5 Research and Development Foundation of Seoul National University. Risk assessment in semiconductor industry: Part 1. Exposure assessment. Research Report; 2009.
6 Yao D, Pardon A, Van Hoornick N, Lievens P. Process risk assessment of semiconductor wet chemical cleaning techniques. Group T Engineering College; 2007.
7 Byun K, Won YL, Hwang YI, Koh DH, Im H, Kim EA. Assessment of arsenic exposure by measurement of urinary speciated inorganic arsenic metabolites in workers in a semiconductor manufacturing plant. Ann Occup Environ Med 2013;25:21.   DOI
8 Beall C, Bender TJ, Cheng H, Herrick R, Kahn A, Matthews R, Sathiakumar N, Schymura M, Stewart J, Delzell E. Mortality among semiconductor and storage device-manufacturing workers. J Occup Environ Med 2005;47:996-1014.   DOI
9 Bender TJ, Beall C, Cheng H, Herrick RF, Kahn AR, Matthews R, Sathiakumar N, Schymura M, Stewart J, Delzell E. Cancer incidence among semiconductor and electronic storage device workers. Occup Environ Med 2007;64:30-6.   DOI
10 Boice Jr JD, Marano DE, Munro HM, Chadda BK, Signorello LB, Tarone RE, Blot WJ, McLaughlin JK. Cancer mortality among US workers employed in semiconductor wafer fabrication. J Occup Environ Med 2010;52:1082-97.   DOI
11 Darnton A, Wilkinson S, Miler B, MacCalman L, Galea K, Shafrir A, Cherrie J, McElvenny D, Osman J. A further study of cancer among the current and former employees of National Semiconductor (UK) Ltd. Greenock. Sudbury, Suffolk (UK): Health and Safety Executive and Institute of Occupational Medicine; 2010. 135 p.
12 McElvenny DM, Darnton AJ, Hodgson JT, Clarke SD, Elliott RC, Osman J. Investigation of cancer incidence and mortality at a Scottish semiconductor manufacturing facility. Occup Med 2003;53:419-30.   DOI
13 Nichols L, Sorahan T. Cancer incidence and cancer mortality in a cohort of UK semiconductor workers, 1970-2002. Occup Med 2005;55:625-30.   DOI
14 Sorahan T, Pope D, McKiernan M. Cancer incidence and cancer mortality in a cohort of semiconductor workers: an update. Br J Ind Med 1992;49:215. PMCID: PMC1012097.
15 Ministry of Health and Welfare. National cancer registration and statistics system. In: Annual report of cancer statistics in Korea in 2009 2011. Available from: https://ncrs.cancer.go.kr/; 2011.
16 Sorahan T, Waterhouse J, McKiernan M, Aston R. Cancer incidence and cancer mortality in a cohort of semiconductor workers. Occup Environ Med 1985;42:546-50.   DOI
17 Lee HE, Kim EA, Park JS, Kang SK. Cancer mortality and incidence in Korean semiconductor workers. Saf Health Work 2011;2:135-47.   DOI
18 Statistics Korea. The statistics for cause of death in 2009; 2009. Available from: http://kostat.go.kr/.
19 Kim EA, Lee HE, Ryu HW, Park SH, Kang SK. Cases series of malignant lymphohematopoietic disorder in Korean semiconductor industry. Saf Health Work 2011;2:122-34.   DOI
20 Issaragrisil S, Kaufman DW, Anderson T, Chansung K, Leaverton PE, Shapiro S, Neal SY. The epidemiology of aplastic anemia in Thailand. Blood 2006;107:1299-307.   DOI
21 Muir K, Chilvers C, Harriss C, Coulson L, Grainge M, Darbyshire P, Hows CGJ, Marsh J, Rutherford T, Taylor M, Gordon-Smith EC. The role of occupational and environmental exposures in the aetiology of acquired severe aplastic anaemia: a case control investigation. Brit J Haematol 2003;123:906-14.   DOI
22 Young NS, Kaufman DW. The epidemiology of acquired aplastic anemia. Haematologica 2008;93:489-92.   DOI
23 Goldstein BD. Benzene toxicity: a critical evaluation: hematotoxicity in humans. J Tox Environ Health Suppl 1977;2:69-105. PMID:342717.
24 Korea Ministry of Employment and Labor. Industrial accident compensation insurance act; 2017. Available from: http://www.law.go.kr/.
25 Park HH, Jang JK, Shin JA. Quantitative exposure assessment of various chemical substances in a wafer fabrication industry facility. Saf Health Work 2011;2:39-51.   DOI
26 Chung EK, Kim KB, Chung KJ, Lee IS, You KH, Park JS. Occupational exposure of semiconductor workers to ELF magnetic fields. J Korean Soc Occup Environ Hyg 2012;22:42-51.
27 Abdollahzadeh S, Katharine SH, Schenker MB. A model for assessing occupational exposure to extremely low-frequency magnetic fields in fabrication rooms in the semiconductor health study. Am J Ind Med 1995;28:723-34.   DOI
28 Choi S, Cha W, Park J, Kim S, Kim W, Yoon S, Park JH, Ha K, Park D. Extremely low frequency-magnetic fields (ELF-MF) exposure characteristics among semiconductor workers. Int J Environ Res Public Health 2018;15:642.   DOI
29 Hakansson N, Stenlund C, Gustavsson P, Johansen C, Floderus B. Arc and resistance welding and tumours of the endocrine glands: a Swedish case-control study with focus on extremely low frequency magnetic fields. Occup Environ Med 2005;62:304-8.   DOI
30 Navas-Acien A, Pollan M, Gustavsson P, Floderus B, Plato N, Dosemeci M. Interactive effect of chemical substances and occupational electromagnetic field exposure on the risk of gliomas and meningiomas in Swedish men. Cancer Epidemiol Biomarkers Prev 2002;11:1678-83.
31 Van Zant P. Microchip fabrication: a practical guide to semiconductor processing. New York: McGrawHill; 2004. p. 63-4.
32 Richter T, Nestler-Parr S, Babela R, Khan ZM, Tesoro T, Molsen E, Hughes DA. Rare disease terminology and definitions-a systematic global review: report of the ISPOR rare disease special interest group. Value Health 2015;18:906-14.   DOI
33 Park JY. History of development in Korea semiconductor industry. Korea Semiconductor Industry Association; 2012.
34 Marano DE, Boice Jr JD, Munro HM, Chadda BK, Williams ME, McCarthy CM, Kivel PF, Blot WJ, McLaughlin JK. Exposure assessment among US workers employed in semiconductor wafer fabrication. J Occup Environ Med 2010;52:1075-81.   DOI
35 Wald PH, Jones JR. Semiconductor manufacturing: an introduction to processes and hazards. Am J Ind Med 1987;11:203-21.   DOI
36 Harrison M. Semiconductor manufacturing hazards. In: Hazardous materials toxicology: clinical principles of environmental health. Williams & Wilkins; 1992. p. 472-504.
37 Chelton C, Glowatz M, Mosovsky J. Chemical hazards in the semiconductor industry. IEEE Trans Educ 1991;34:269-88.   DOI