Browse > Article
http://dx.doi.org/10.4142/jvs.21235

Prevalence of hepatitis E virus antibodies in cattle in Burkina Faso associated with swine mixed farming  

Tialla, Dieudonne (Unit of Epidemic-Prone Diseases, Emerging Diseases and Zoonoses (UMEMEZ), National Influenza Reference Laboratory (LNR-G), Department of Biomedical and Public Health, Health Science Research Institute (IRSS), National Centre for Scientific and Technological Research (CNRST))
Cisse, Assana (Unit of Epidemic-Prone Diseases, Emerging Diseases and Zoonoses (UMEMEZ), National Influenza Reference Laboratory (LNR-G), Department of Biomedical and Public Health, Health Science Research Institute (IRSS), National Centre for Scientific and Technological Research (CNRST))
Ouedraogo, Georges Anicet (Laboratory of Research and Teaching in Health and Animal Biotechnology (LARESBA), University Nazi Boni)
Hubschen, Judith M. (Clinical and Applied Virology Group, Department of Infection and Immunity, Luxembourg Institute of Health (LIH))
Tarnagda, Zekiba (Unit of Epidemic-Prone Diseases, Emerging Diseases and Zoonoses (UMEMEZ), National Influenza Reference Laboratory (LNR-G), Department of Biomedical and Public Health, Health Science Research Institute (IRSS), National Centre for Scientific and Technological Research (CNRST))
Snoeck, Chantal J. (Clinical and Applied Virology Group, Department of Infection and Immunity, Luxembourg Institute of Health (LIH))
Publication Information
Journal of Veterinary Science / v.23, no.3, 2022 , pp. 33.1-33.10 More about this Journal
Abstract
Background: Endemic circulation of human-specific hepatitis E virus (HEV) genotypes 1 and 2 may occult the importance of sporadic zoonotic HEV transmissions in Africa. Increasing numbers of studies reporting anti-HEV antibodies in cattle and the discovery of infectious HEV in cow milk has raised public health concern, but cattle exposure has seldom been investigated in Africa. Objectives: This study aimed at investigating the role of cows in the epidemiology of HEV in Burkina Faso and farmers habits in terms of dairy product consumption as a prerequisite to estimate the risk of transmission to humans. Methods: Sera from 475 cattle and 192 pigs were screened for the presence of anti-HEV antibodies while HEV RNA in swine stools was detected by reverse transcription polymerase chain reaction. Data on mixed farming, dairy product consumption and selling habits were gathered through questionnaires. Results: The overall seroprevalence in cattle was 5.1% and herd seroprevalence reached 32.4% (11/34). Herd seropositivity was not associated with husbandry practice or presence of rabbits on the farms. However, herd seropositivity was associated with on-site presence of pigs, 80.7% of which had anti-HEV antibodies. The majority of farmers reported to preferentially consume raw milk based dairy products. Conclusions: Concomitant presence of pigs on cattle farms constitutes a risk factor for HEV exposure of cattle. However, the risk of HEV infections associated with raw cow dairy product consumption is currently considered as low.
Keywords
Seroprevalence; Hepatitis E; Cattle; Zoonosis; Public Health; Burkina Faso;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Bagulo H, Majekodunmi AO, Welburn SC. Hepatitis E in Sub Saharan Africa - A significant emerging disease. One Health. 2020;11:100186.   DOI
2 EFSA Panel on Biological Hazards (BIOHAZ)Ricci A, Allende A, Bolton D, Chemaly M, Davies R, et al. Public health risks associated with hepatitis E virus (HEV) as a food-borne pathogen. EFSA J. 2017;15(7):e04886.
3 Traore KA, Rouamba H, Nebie Y, Sanou M, Traore AS, Barro N, et al. Seroprevalence of fecal-oral transmitted hepatitis A and E virus antibodies in Burkina Faso. PLoS One. 2012;7(10):e48125.   DOI
4 Modiyinji AF, Sanding GM, Atsama MA, Monamele CG, Nola M, Njouom R. Serological and molecular investigation of hepatitis E virus in pigs reservoirs from Cameroon reveals elevated seroprevalence and presence of genotype 3. PLoS One. 2020;15(2):e0229073.   DOI
5 Junaid SA, Agina SE, Abubakar KA. Epidemiology and associated risk factors of hepatitis e virus infection in plateau state, Nigeria. Virology (Auckl). 2014;5:15-26.
6 Tei S, Kitajima N, Takahashi K, Mishiro S. Zoonotic transmission of hepatitis E virus from deer to human beings. Lancet. 2003;362(9381):371-373.   DOI
7 Arankalle VA, Joshi MV, Kulkarni AM, Gandhe SS, Chobe LP, Rautmare SS, et al. Prevalence of anti-hepatitis E virus antibodies in different Indian animal species. J Viral Hepat. 2001;8(3):223-227.   DOI
8 El-Duah P, Dei D, Binger T, Sylverken A, Wollny R, Tasiame W, et al. Detection and genomic characterization of hepatitis E virus genotype 3 from pigs in Ghana, Africa. One Health Outlook. 2020;2(1):10.   DOI
9 Yan B, Zhang L, Gong L, Lv J, Feng Y, Liu J, et al. Hepatitis E virus in yellow cattle, Shandong, Eastern China. Emerg Infect Dis. 2016;22(12):2211-2212.   DOI
10 Huang F, Li Y, Yu W, Jing S, Wang J, Long F, et al. Excretion of infectious hepatitis E virus into milk in cows imposes high risks of zoonosis. Hepatology. 2016;64(2):350-359.   DOI
11 Go HJ, Park BJ, Ahn HS, Lyoo EL, Kim DH, Lee JB, et al. Identification of hepatitis E virus in bovine and porcine raw livers. J Microbiol Biotechnol. 2019;29(12):2022-2025.   DOI
12 Tialla D, Dahourou LD, Gbati OB. Seroprevalence and factors associated with bovine and swine toxoplasmosis in Bobo-Dioulasso, Burkina Faso. Vet World. 2019;12(10):1519-1523.   DOI
13 Tritz SE, Khounvisith V, Pommasichan S, Ninnasopha K, Keosengthong A, Phoutana V, et al. Evidence of increased hepatitis E virus exposure in Lao villagers with contact to ruminants. Zoonoses Public Health. 2018;65(6):690-701.   DOI
14 Rivero-Juarez A, Frias M, Rodriguez-Cano D, Cuenca-Lopez F, Rivero A. Isolation of hepatitis E virus from breast milk during acute infection. Clin Infect Dis. 2016;62(11):1464.
15 Forgach P, Nowotny N, Erdelyi K, Boncz A, Zentai J, Szucs G, et al. Detection of hepatitis E virus in samples of animal origin collected in Hungary. Vet Microbiol. 2010;143(2-4):106-116.   DOI
16 Peralta B, Casas M, de Deus N, Martin M, Ortuno A, Perez-Martin E, et al. Anti-HEV antibodies in domestic animal species and rodents from Spain using a genotype 3-based ELISA. Vet Microbiol. 2009;137(1-2):66-73.   DOI
17 Bouwknegt M, Frankena K, Rutjes SA, Wellenberg GJ, de Roda Husman AM, van der Poel WH, et al. Estimation of hepatitis E virus transmission among pigs due to contact-exposure. Vet Res. 2008;39(5):40.   DOI
18 Dziedzinska R, Krzyzankova M, Bena M, Vasickova P. Evidence of hepatitis E virus in goat and sheep milk. Viruses. 2020;12(12):1429.   DOI
19 Aspinall EJ, Couturier E, Faber M, Said B, Ijaz S, Tavoschi L, et al. Hepatitis E virus infection in Europe: surveillance and descriptive epidemiology of confirmed cases, 2005 to 2015. Euro Surveill. 2017;22(26):30561.
20 Kamar N, Bendall R, Legrand-Abravanel F, Xia NS, Ijaz S, Izopet J, et al. Hepatitis E. Lancet. 2012;379(9835):2477-2488.   DOI
21 Xu F, Pan Y, Baloch AR, Tian L, Wang M, Na W, et al. Hepatitis E virus genotype 4 in yak, northwestern China. Emerg Infect Dis. 2014;20(12):2182-2184.   DOI
22 Ouoba JB, Traore KA, Rouamba H, Setondji KV, Minoungou GL, Ouoba BL, et al. Prevalence of anti-hepatitis E virus antibodies in domestic animal from three representative provinces of Burkina Faso. Vet Anim Sci. 2019;7:100059.   DOI
23 Barnaud E, Rogee S, Garry P, Rose N, Pavio N. Thermal inactivation of infectious hepatitis E virus in experimentally contaminated food. Appl Environ Microbiol. 2012;78(15):5153-5159.   DOI
24 Doceul V, Bagdassarian E, Demange A, Pavio N. Zoonotic hepatitis E virus: classification, animal reservoirs and transmission routes. Viruses. 2016;8(10):270.   DOI
25 Traore KA, Ouoba JB, Rouamba H, Nebie YK, Dahourou H, Rossetto F, et al. Hepatitis E virus prevalence among blood donors, Ouagadougou, Burkina Faso. Emerg Infect Dis. 2016;22(4):755-757.
26 Dimeglio C, Kania D, Mantono JM, Kagone T, Zida S, Tassembedo S, et al. Hepatitis E virus infections among patients with acute febrile jaundice in Burkina Faso. Viruses. 2019;11(6):554.   DOI
27 Owolodun OA, Gerber PF, Gimenez-Lirola LG, Kwaga JK, Opriessnig T. First report of hepatitis E virus circulation in domestic pigs in Nigeria. Am J Trop Med Hyg. 2014;91(4):699-704.   DOI
28 Matsuda H, Okada K, Takahashi K, Mishiro S. Severe hepatitis E virus infection after ingestion of uncooked liver from a wild boar. J Infect Dis. 2003;188(6):944.   DOI
29 Dong C, Meng J, Dai X, Liang JH, Feagins AR, Meng XJ, et al. Restricted enzooticity of hepatitis E virus genotypes 1 to 4 in the United States. J Clin Microbiol. 2011;49(12):4164-4172.   DOI
30 El-Tras WF, Tayel AA, El-Kady NN. Seroprevalence of hepatitis E virus in humans and geographically matched food animals in Egypt. Zoonoses Public Health. 2013;60(3):244-251.   DOI
31 Yu Y, Sun J, Liu M, Xia L, Zhao C, Harrison TJ, et al. Seroepidemiology and genetic characterization of hepatitis E virus in the northeast of China. Infect Genet Evol. 2009;9(4):554-561.   DOI
32 Antia RE, Adekola AA, Jubril AJ, Ohore OG, Emikpe BO. Hepatitis E virus infection seroprevalence and the associated risk factors in animals raised in Ibadan, Nigeria. J Immunoassay Immunochem. 2018;39(5):509-520.   DOI
33 Yugo DM, Cossaboom CM, Heffron CL, Huang YW, Kenney SP, Woolums AR, et al. Evidence for an unknown agent antigenically related to the hepatitis E virus in dairy cows in the United States. J Med Virol. 2019;91(4):677-686.   DOI
34 Prpic J, Cerni S, Skoric D, Keros T, Brnic D, Cvetnic Z, et al. Distribution and molecular characterization of hepatitis E virus in domestic animals and wildlife in Croatia. Food Environ Virol. 2015;7(3):195-205.   DOI
35 Traore KA, Ouoba JB, Huot N, Rogee S, Dumarest M, Traore AS, et al. Hepatitis E virus exposure is increased in pork butchers from Burkina Faso. Am J Trop Med Hyg. 2015;93(6):1356-1359.   DOI
36 Geng Y, Wang C, Zhao C, Yu X, Harrison TJ, Tian K, et al. Serological prevalence of hepatitis E virus in domestic animals and diversity of genotype 4 hepatitis E virus in China. Vector Borne Zoonotic Dis. 2010;10(8):765-770.   DOI
37 Demirci M, Yigin A, unlu O, Kilic Altun S. Detection of HEV RNA amounts and genotypes in raw milks obtained from different animals. Mikrobiyol Bul. 2019;53(1):43-52.   DOI
38 Khuroo MS. Discovery of hepatitis E: the epidemic non-A, non-B hepatitis 30 years down the memory lane. Virus Res. 2011;161(1):3-14.   DOI
39 Vitral CL, Pinto MA, Lewis-Ximenez LL, Khudyakov YE, dos Santos DR, Gaspar AM. Serological evidence of hepatitis E virus infection in different animal species from the Southeast of Brazil. Mem Inst Oswaldo Cruz. 2005;100(2):117-122.   DOI
40 Vercouter AS, Sayed IM, Lipkens Z, De Bleecker K, De Vliegher S, Colman R, et al. Absence of zoonotic hepatitis E virus infection in Flemish dairy cows. Int J Food Microbiol. 2018;281:54-59.   DOI
41 Sayed IM, Elkhawaga AA, El-Mokhtar MA. Circulation of hepatitis E virus (HEV) and/or HEV-like agent in non-mixed dairy farms could represent a potential source of infection for Egyptian people. Int J Food Microbiol. 2020;317:108479.   DOI
42 S de Paula V, Wiele M, Mbunkah AH, Daniel AM, Kingsley MT, Schmidt-Chanasit J. Hepatitis E virus genotype 3 strains in domestic pigs, Cameroon. Emerg Infect Dis. 2013;19(4):666-668.