Transcriptome sequencing revealed the inhibitory mechanism of ketoconazole on clinical Microsporum canis |
Wang, Mingyang
(Key Laboratory of Livestock Infectious Diseases in Northeast China, Ministry of Education, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University)
Zhao, Yan (Key Laboratory of Livestock Infectious Diseases in Northeast China, Ministry of Education, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University) Cao, Lingfang (Key Laboratory of Livestock Infectious Diseases in Northeast China, Ministry of Education, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University) Luo, Silong (Key Laboratory of Livestock Infectious Diseases in Northeast China, Ministry of Education, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University) Ni, Binyan (Qingdao Vetlab Biotechnology Co., Ltd.) Zhang, Yi (Key Laboratory of Livestock Infectious Diseases in Northeast China, Ministry of Education, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University) Chen, Zeliang (Key Laboratory of Livestock Infectious Diseases in Northeast China, Ministry of Education, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University) |
1 | Keene JD. Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome. Proc Natl Acad Sci U S A. 2001;98(13):7018-7024. DOI |
2 | Ginter-Hanselmayer G, Weger W, Ilkit M, Smolle J. Epidemiology of tinea capitis in Europe: current state and changing patterns. Mycoses. 2007;50 Suppl 2:6-13. DOI |
3 | Ghannoum MA, Rice LB. Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance. Clin Microbiol Rev. 1999;12(4):501-517. DOI |
4 | Wang Z, Gerstein M, Snyder M. RNA-Seq: a revolutionary tool for transcriptomics. Nat Rev Genet. 2009;10(1):57-63. DOI |
5 | Sheehan DJ, Hitchcock CA, Sibley CM. Current and emerging azole antifungal agents. Clin Microbiol Rev. 1999;12(1):40-79. DOI |
6 | Lepesheva GI, Waterman MR. Sterol 14alpha-demethylase cytochrome P450 (CYP51), a P450 in all biological kingdoms. Biochim Biophys Acta. 2007;1770(3):407-477. |
7 | Nowosielski M, Hoffmann M, Wyrwicz LS, Stepniak P, Plewczynski DM, Lazniewski M, et al. Detailed mechanism of squalene epoxidase inhibition by terbinafine. J Chem Inf Model. 2011;51(2):455-462. DOI |
8 | Morio F, Pagniez F, Lacroix C, Miegeville M, Le Pape P. Amino acid substitutions in the Candida albicans sterol Δ5,6-desaturase (Erg3p) confer azole resistance: characterization of two novel mutants with impaired virulence. J Antimicrob Chemother. 2012;67(9):2131-2138. DOI |
9 | Yang J, Zhang KQ. Chitin synthesis and degradation in fungi: biology and enzymes. Adv Exp Med Biol. 2019;1142:153-167. DOI |
10 | Lockhart DJ, Winzeler EA. Genomics, gene expression and DNA arrays. Nature. 2000;405:827-836. DOI |
11 | Zhang J, Li L, Lv Q, Yan L, Wang Y, Jiang Y. The fungal CYP51s: their functions, structures, related drug resistance, and inhibitors. Front Microbiol. 2019;10:691. DOI |
12 | Borgers M, Van den Bossche H, De Brabander M. The mechanism of action of the new antimycotic ketoconazole. Am J Med. 1983;74(1B):2-8. |
13 | Costa V, Angelini C, De Feis I, Ciccodicola A. Uncovering the complexity of transcriptomes with RNA-Seq. J Biomed Biotechnol. 2010;2010:853916. |
14 | Sanati H, Belanger P, Fratti R, Ghannoum M. A new triazole, voriconazole (UK-109,496), blocks sterol biosynthesis in Candida albicans and Candida krusei. Antimicrob Agents Chemother. 1997;41(11):1249-6. |
15 | Konecna A, Toth Hervay N, Valachovic M, Gbelska Y. ERG6 gene deletion modifies Kluyveromyces lactis susceptibility to various growth inhibitors. Yeast. 2016;33(12):621-632. DOI |
16 | Ruiz-Herrera J, San-Blas G. Chitin synthesis as target for antifungal drugs. Curr Drug Targets Infect Disord. 2003;3(1):77-91. DOI |
17 | Shen Q, Zheng X, McNutt MA, Guang L, Sun Y, Wang J, et al. NAT10, a nucleolar protein, localizes to the midbody and regulates cytokinesis and acetylation of microtubules. Exp Cell Res. 2009;315(10):1653-1667. DOI |
18 | Neyer S, Kunz M, Geiss C, Hantsche M, Hodirnau VV, Seybert A, et al. Structure of RNA polymerase I transcribing ribosomal DNA genes. Nature. 2016;540(7634):607-610. DOI |
19 | Hopper AK, Nostramo RT. tRNA Processing and subcellular trafficking proteins multitask in pathways for other RNAs. Front Genet. 2019;10:96. DOI |
20 | Verma SB. Emergence of recalcitrant dermatophytosis in India. Lancet Infect Dis. 2018;18(7):718-719. DOI |
21 | Binder B, Lackner HK, Poessl BD, Propst E, Weger W, Smolle J, et al. Prevalence of tinea capitis in Southeastern Austria between 1985 and 2008: up-to-date picture of the current situation. Mycoses. 2011;54(3):243-247. DOI |
22 | Vanden Bossche H, Marichal P, Le Jeune L, Coene MC, Gorrens J, Cools W. Effects of itraconazole on cytochrome P-450-dependent sterol 14 alpha-demethylation and reduction of 3-ketosteroids in Cryptococcus neoformans. Antimicrob Agents Chemother. 1993;37(10):2101-2105. DOI |
23 | Xiao CW, Ji QA, Wei Q, Liu Y, Bao GL. Antifungal activity of berberine hydrochloride and palmatine hydrochloride against Microsporum canis -induced dermatitis in rabbits and underlying mechanism. BMC Complement Altern Med. 2015;15(4):177. DOI |
24 | Vannini A. A structural perspective on RNA polymerase I and RNA polymerase III transcription machineries. Biochim Biophys Acta. 2013;1829(3-4):258-264. DOI |
25 | Bond R, Morris DO, Guillot J, Bensignor EJ, Robson D, Mason KV, et al. Biology, diagnosis and treatment of Malassezia dermatitis in dogs and cats: clinical consensus guidelines of the world association for veterinary dermatology. Vet Dermatol. 2020;31(1):75. DOI |
26 | Yin B, Xiao Y, Ran Y, Kang D, Dai Y, Lama J. Microsporum canis infection in three familial cases with tinea capitis and tinea corporis. Mycopathologia. 2013;176(3-4):259-265. DOI |
27 | Anemuller W, Baumgartner S, Brasch J. Atypical Microsporum canis variant in an immunosuppressed child. J Dtsch Dermatol Ges. 2008;6(6):473-475. DOI |
28 | Aneke CI, Otranto D, Cafarchia C. Therapy and antifungal susceptibility profile of Microsporum canis. J Fungi (Basel). 2018;4(3):107. DOI |
29 | Vanden Bossche H. Biochemical targets for antifungal azole derivatives: hypothesis on the mode of action. Curr Top Med Mycol. 1985;1:313-351. DOI |
30 | Ghannoum MA, Spellberg BJ, Ibrahim AS, Ritchie JA, Currie B, Spitzer ED, et al. Sterol composition of Cryptococcus neoformans in the presence and absence of fluconazole. Antimicrob Agents Chemother. 1994;38(9):2029-2033. DOI |
31 | Xiao CW, Ji QA, Wei Q, Liu Y, Pan LJ, Bao GL. Digital gene expression analysis of Microsporum canis exposed to berberine chloride. PLoS One. 2015;10(4):e0124265. DOI |
32 | Galani K, Nissan TA, Petfalski E, Tollervey D, Hurt E. Rea1, a dynein-related nuclear AAA-ATPase, is involved in late rRNA processing and nuclear export of 60 S subunits. J Biol Chem. 2004;279(53):55411-55418. DOI |
33 | Lepesheva GI, Friggeri L, Waterman MR. CYP51 as drug targets for fungi and protozoan parasites: past, present and future. Parasitology. 2018;145(14):1820-1836. DOI |
34 | Zare B, Sepehrizadeh Z, Faramarzi MA, Soltany-Rezaee-Rad M, Rezaie S, Shahverdi AR. Antifungal activity of biogenic tellurium nanoparticles against Candida albicans and its effects on squalene monooxygenase gene expression. Biotechnol Appl Biochem. 2014;61(4):395-400. DOI |